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Molecular Diagnostics

Image: The QuantStudio 12K Flex real-time PCR instrument (Photo courtesy of ANDbio).

Real-Time PCR Assay Developed for Detection of Candida

Vulvovaginal candidiasis (VVC) is a common condition characterized by vulvovaginal inflammation in combination with detection of one or more of several Candida species and after bacterial vaginosis, VVC is the second most common cause of vulvovaginitis. More...
09 Feb 2017
Image: A prostate cancer cell (Photo courtesy of ABM).

DNA Signature Linked to Prostate Cancer Severity

From extensive genomic analyses of localized, non-indolent prostate cancer (PrCa), researchers have succeeded to identify differences in mutational profiles between localized intermediate risk and metastatic, castrate-resistant PrCa. More...
08 Feb 2017
Image: A histopathology of a desmoplastic-nodular medulloblastoma, stained for reticulin. Reticulin fibers permeate the tumor but are absent in the center of the nodule (Photo courtesy of Dr. Dimitri Agamanolis, MD).

Precision Medicine Advances Pediatric Brain Tumor Diagnosis

Targeted therapies for cancer have significantly improved the treatment of certain types of leukemia, digestive system tumors, and breast cancer, among other malignancies. More...
02 Feb 2017
Image: The circulating tumor cells (CTC)-iChip is composed of two separate microfluidic devices that house three different microfluidic components engineered for inline operations (Photo courtesy of Massachusetts General Hospital).

Digital CTC Assay Improves Liver Cancer Diagnosis

Liver cancer, including hepatocellular carcinoma (HCC), is the second highest cause of cancer death in the world. HCC is particularly prevalent in developing countries, where its incidence is driven by infection with the hepatitis B virus, which now affects more than 248 million individuals. More...
01 Feb 2017
Image: A Single Nucleotide Polymorphism (SNP) is a change of a nucleotide at a single base-pair location on DNA. The upper DNA molecule differs from the lower DNA molecule at a single base-pair location (a C/A polymorphism) (Photo courtesy of David Eccles).

Noninvasive Prenatal Testing of Single Gene Diseases Developed

An approach that allows for the noninvasive assessment of both maternally and paternally inherited mutations involves the analysis of single nucleotide polymorphisms (SNPs) in maternal plasma DNA with reference to parental haplotype information. More...
01 Feb 2017
Image: The Ebola virus in human blood (Photo courtesy of Medical Xpress).

Gene Panel Differentiates Survival Outcomes in Humans Infected with Ebola

A team of molecular virologists used transcriptome data from individuals infected with Ebola virus and from convalescent patients recovering from the disease to identify early stage host factors that were associated with the acute illness and those that differentiated patients who survived from those that died. More...
31 Jan 2017
Image: Three typical trophozoites of Plasmodium ovale in a thin blood smear; note the fimbriation and Schüffner\'s dots (Photo courtesy of the Centre for Agriculture and Bioscience International).

LAMP-Kit Diagnoses Non-Falciparum Malaria

Malaria incidence has recently been declining globally, although in many African countries it is still one of the top health problems and the efforts to control and eradicate malaria will still need a strong diagnostic capacity, which allows any parasitaemic patient to be detected and treated sooner. More...
26 Jan 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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