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Pathology

Image: A scanning electron micrograph (SEM) showing T cells surrounding a breast cancer cell. Testing for immune \'hotspots\' can predict the risk that breast cancer will return (Photo courtesy of Sebastian Kaulitzki.

Immune Infiltration Test Predicts Cancer Relapse Risk

Estrogen receptor-positive (ER+) subtype accounts for about 80% of all breast cancers, the most common cancer in women. At diagnosis, the majority of ER+ patients have a good prognosis if treated with endocrine therapy. More...
24 Aug 2017
Image: A histologic section of a colonic adenoma containing invasive carcinoma (Photo courtesy of Dr. Mauro Risio).

New Molecular Test Identifies Colorectal Cancer

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, with more than 600,000 deaths each year. Among individuals undergoing treatment for the disease, recurrence occurs in 30% to 50% of all cases. The majority of these cases present in the first two to three years following initial diagnosis and treatment. More...
23 Aug 2017
Image: An arthrogram is used to help confirm periprosthetic joint infection (Photo courtesy of Dr. Robin Smithuis, MD).

Preoperative Bacteriuria Unconnected to Joint Infection

Patients who undergo elective joint replacement are traditionally screened and treated for preoperative bacteriuria in order to prevent periprosthetic joint infection (PJI), but more recently, this practice has been questioned. More...
22 Aug 2017
Image: The model illustrates clinical implications of BCBM CTC screening method for brain micro-metastasis before they become detectable by MRI. BCBM-associated CTCs can be used as a tool to evaluate responses to therapy for BCBM patients (Photo courtesy of Houston Methodist).

Blood Test Detects Brain Metastases While Treatable

A blood test is being generated that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time. More...
16 Aug 2017
Image: The new fabric-based Velcro-like device (top), and the currently used standard metal scraping-device (bottom) (Photo courtesy of J. Diedrich, UC Riverside).

New Device Provides Better Biopsies for Cancer Testing

In a study comparing a new frictional fabric brush versus the currently used sharp scraper for endocervical curettage, the new device provided better tissue yield with less pain and discomfort. More...
14 Aug 2017
Image: The Ion Ampliseq library preparation kits (Photo courtesy of Thermo Fisher Scientific).

Liquid Biopsy Could Identify Advanced Breast Cancer Patients

A novel blood test has been developed that measures genetic changes in circulating cancer DNA that could help identify patients with metastatic breast cancer who could benefit from a change of treatment. More...
09 Aug 2017
Image: Breast cancer: immunohistochemical comparison of three estrogen receptor antibodies: A through C, 1D5 and 6F11 show negativity, whereas SP1 shows positivity (Photo courtesy of Stanford University Medical Center).

Hormone Receptor Antibody Reagents Assessed for Breast Cancer

Immunohistochemical analysis of estrogen receptor (ER) and progesterone receptor (PgR) expression in breast cancer is the current standard of care and directly determines therapy. More...
08 Aug 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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