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Microbiology

Image: Confocal fluorosence microscopy of human aortic smooth muscle cells infected with the periodontal pathogen P. gingivalis (Photo courtesy of Zhang B et al., 2015, and the journal Infection and Immunity).

Connecting Molecular Dots of the Association Between Periodontitis and Heart Disease

Periodontitis is a risk factor for heart disease. Researchers have now shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in aortic smooth muscle cells.   More...
27 Sep 2015
Image: In the new nanozyme immunochromatographic strip test for Ebolavirus (EBOV), the magnetic (A) and catalytic (B) properties of the nanozymes (Fe3O4 magnetic nanoparticles (MNPs)) make the signal 100 times stronger than standard strips with colloidal-gold nanoparticles, generating a deeper color reaction that can be more clearly seen by the naked eye (Image courtesy of Duan D et al., 2015, and Elsevier).

Sensitive Nanozyme Test May Provide Rapid Point-of-Care Diagnosis of Ebola

Researchers have developed a simple low-cost Ebolavirus test based on detection technology using magnetic nanoparticles that has shown 100x higher sensitivity than the standard immunochromatographic ELISA gold strip test.   More...
24 Sep 2015
Image: Firefly Dx prototype system is designed to provide real-time, accurate results on a handheld point-of-care, point-of-need device, with applications in diagnostic pathogen detection, agricultural and food screening, and detection of biological weapons agents (Photo courtesy of PositiveID Corporation).

Successful C. difficile Test Expands Diagnostic Capability for Hospital Acquired Infections

A new, more comprehensive Clostridium difficile test was added to the panel of pathogens successfully detected on a prototype system for PCR based rapid diagnostic tests.  More...
23 Sep 2015
Image: Mycobacterium tuberculosis (stained purple) in a tissue specimen (blue) (Photo courtesy of the CDC – [US] Centers for Disease Control and Prevention).

Rapid Tests Match Culture Gold Standard for Diagnosing Drug-Resistant Tuberculosis

A recent paper compared three "rapid" tests for diagnosis of drug-resistant tuberculosis to the standard culture technique, which can take up to a month to yield results.  More...
21 Sep 2015
Image: The Verigene Test Cartridge designed for multiplex analysis of one patient sample and used with the Verigene System (Photo courtesy of Nanosphere).

Flex Nucleic Acid Test Identifies Respiratory Pathogens

The first test of its kind, which features proprietary software, allows the 16 viral and bacterial targets identified by the assay to be reported as a full multiplex panel or in various user-defined subsets.  More...
21 Sep 2015
Image: Yellow-green fluorescence of Clostridium difficile inoculated onto cefoxitin-cycloserine-fructose agar (CCFA) plates (Photo courtesy of Center of Disease Control and Prevention).

Multiple Clostridium Difficile Strains Cause Severe Patient Outcomes

Clostridium difficile is the most common cause of hospital acquired infections in the USA and the incidence of C. difficile infection has increased dramatically since 2001, coinciding with the emergence of the epidemic ribotype 027.   More...
08 Sep 2015
Image: The paper-strip test differentiates Ebola, dengue and yellow fever (Photo courtesy of Dr. Chun-Wan Yen).

Paper-Based Test Rapidly Diagnose Viral Diseases in Remote Areas

A paper-based device has been developed that changes color, depending on whether the patient has Ebola, yellow fever or dengue and will facilitate diagnosis in remote, low-resource settings.    More...
07 Sep 2015
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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