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Microbiology

Image: In the retrospective cohort study, fluoroquinolone resistance mutation detection assay was found to be equivalent to culture-based drug sensitivity testing in predicting multidrug-resistant tuberculosis treatment outcome (Photo courtesy of Harvard Medical School).

Molecular Tests Predict TB Treatment Outcome

New molecular tests are gaining popularity as a rapid way to detect genetic mutations that render tuberculosis (TB) impervious to drugs. Yet, how well these new tests fare in gauging risk of actual drug failure has remained unclear. Researchers have now found that molecular tests that detect resistance to the fluoroquinolones class of TB drugs may be at least as good as traditional drug-sensitivity tests conducted with lab cultures. More...
14 Aug 2017
Image: The FilmArray respiratory panel enables rapid and accurate automated detection of pathogens causing respiratory infections (Photo courtesy of Idaho Technologies).

Test Discriminates Between Viral and Bacterial Infections

Lower respiratory tract infection (LRTI) commonly causes hospitalization in adults but because bacterial diagnostic tests are not accurate, antibiotics are frequently prescribed. Antibiotics are lifesaving drugs, but overuse is leading to antibiotic resistance, one of the world's most pressing health threats. More...
10 Aug 2017
Image: The Professional Standard TRIO thermal cycler provides three independent 48 well blocks and heated lids in one housing (Photo courtesy of Biometra).

Methods Compared for Chagas Disease Diagnosis

Chagas Disease (CD) is a chronic infectious disease caused by the protozoan flagellate Trypanosoma cruzi. In endemic countries, CD is transmitted mainly through the contact with feces of different triatomine bugs. Due to increased migration, CD has become an international health problem. More...
08 Aug 2017
Image: A chart showing the costs associated with TB screening of healthcare workers (Image courtesy of McGill University Health Centre).

TB Screening Recommended for High-Risk Healthcare Workers Only

Routine screening for and treatment of latent tuberculosis (TB) infection has traditionally been an important part of TB prevention in Canadian and US healthcare institutions, but recent data have called into question its cost effectiveness. A new study has found that the current strategy of annual screening of is ineffectively expensive, suggesting that a switch to screening only high-risk healthcare workers is needed. More...
08 Aug 2017
Image: A new blood test has been developed to differentiate Zika virus infection from other flaviviruses (Photo courtesy of Brett Israel, University of California-Berkeley).

New Test Distinguishes Zika from Similar Viral Infections

Zika is a mosquito-borne disease and is linked to severe congenital birth defects. Assays already exist to detect Zika virus infection, but they either work only shortly after infection or are poor at differentiating Zika from other flaviviruses. More...
02 Aug 2017
Image: Immunofluorescent antibody stain showing positive Powassan virus-infected cells (Photo courtesy of Coppe Laboratories).

Powassan Virus Diagnosed in Patients with Tick-Borne Diseases

Powassan virus (POWV) lineage II, also known as deer tick virus, is an emerging tick-borne flavivirus transmitted by Ixodes scapularis ticks, which are also the primary vector for the Lyme disease pathogen Borrelia burgdorferi. More...
02 Aug 2017
Image: The Coulter LH 780 hematology analyzer (Photo courtesy of Beckman Coulter).

Antimicrobial Therapy Biomarker Enumerates Eosinophil Count Changes

Eosinopenia as a criterion of sepsis has been the subject of debate for decades and the pathophysiology of eosinopenia is related to the migration of eosinophils to the inflammatory site, presumably as a result of chemotactic substances secreted during the acute phase of inflammation. More...
01 Aug 2017
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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