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Immunology

Inflammatory Markers Correlated with SCA Pain Intensity

Sickle cell anemia (SCA) is a hereditary hemolytic anemia where the synthesis of hemoglobin (Hb) is abnormal and the inheritance can be heterozygous (HbS) or homozygous (HbSS). Homozygous patients with SCA often develop vaso-occlusive crises (VOCs) and recurrent episodes of hemolysis causing multi-organ infarction and dysfunction. More...
17 Nov 2016
Image: The results from the rapid immunodiagnostic test (RIDT Ag) for rabies (Photo courtesy of the Swiss Tropical and Public Health Institute).

Rapid Rabies Diagnostic Tool Validated for Field Surveillance

Rabies is a viral zoonotic encephalomyelitis transmitted to humans after exposure to infected mammals, mainly dogs, through bites, scratches or licks on damaged skin or mucous membranes. More...
16 Nov 2016
Image: A photomicrograph of Borrelia burgdorferi, the causative pathogen of Lyme disease using dark field microscopy (Photo courtesy of Dr. Jeffrey Nelson, MD).

Genes and Age Determine Susceptibility to Lyme Disease

Despite the importance of immune variation for the symptoms and outcome of Lyme disease, the factors influencing cytokine production during infection with the causal pathogen Borrelia burgdorferi remain poorly understood. More...
16 Nov 2016
Image: The GeneAmp Polymerase Chain Reaction (PCR) System 2400 thermocycler (Photo courtesy of Perkin Elmer).

Cytokine Levels in Transplant Recipients Associated with Cytomegalovirus

Cytomegalovirus seropositivity is an independent risk factor for atherosclerosis in patients with end stage renal disease (ESRD) and donor cytomegalovirus (CMV) seropositivity is associated with higher graft loss. More...
15 Nov 2016

Vitamin D Deficiency Predicts Poor Prognosis for IgA Nephropathy

Immunoglobulin A (IgA) nephropathy (IgAN), also known as Berger’s disease is the most common form of glomerulonephritis worldwide, especially in Asia, and represents one of the main causes of the end-stage renal diseases (ESRD). More...
15 Nov 2016
Image: The Syphilis Health Check test is a qualitative rapid membrane immune-chromatographic assay for the detection of Treponema pallidum (syphilis) antibodies in human whole blood, serum and plasma (Photo courtesy of Trinity Biotech).

Rapid Syphilis Test Evaluated as Tool for Public Health Programs

A rapid commercial treponemal syphilis-screening test is a new tool for public health programs to combat increasing syphilis rates, specifically among persons without a prior syphilis infection. More...
09 Nov 2016
Image: Detail of a CaFlux plate and the green fluorescent read-out from activated immune cells (Photo courtesy of Thomas Jefferson University).

New Method Determines Efficacy of Immune Cells

The frequency of pathogen-specific and tumor-specific T cells and their functional activity reflect the effectiveness of immune responses and can serve as useful diagnostic and prognostic indicators. More...
09 Nov 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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