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BioResearch

Image: Arup and Gitali Indra are beginning to find clues to predicting, preventing and stopping melanoma before it spreads (Photo courtesy of Karl Maasdam / Oregon State University College of Pharmacy).

Melanoma May Be Triggered by Deficit of Retinoid-X-Receptors in Melanocytes

Cancer researchers have linked the development of the deadly skin cancer melanoma to depressed expression in melanocytes of the type II nuclear receptors Retinoid-X-Receptor alpha and Retinoid-X-Receptor beta.   More...
20 May 2014
Image An adeno-associated virus capsid (blue) modified by peptides (red) inserted to lock the virus is the result of research at Rice University into a new way to target cancerous and other diseased cells. The peptides are keyed to proteases overexpressed at the site of diseased tissues; they unlock the capsid and allow it to deliver its therapeutic cargo (Photo courtesy of Junghae Suh/Rice University).

Nanodelivery System Securely Targets Cancer cells

Scientists have devised a tunable virus that works similar to a safe deposit box. It takes two keys to open it and release its therapeutic payload.  More...
20 May 2014
Image: Left ventricular cardiac hypertrophy in short axis view (Photo courtesy of Patrick Lynch).

Possible Target for Gene Therapy May Correct Cardiac Hypertrophy

A deficit in the expression of the protein Erbin has been linked to the development of cardiac hypertrophy and heart failure.  More...
19 May 2014

Potential Drug Target Identified in Mouse Pancreatic Cancer Model

Cancer researchers studying pancreatic cancer have identified Yes-associated protein as a potential drug target whose inhibition would block the activity of the KRAS oncogene.  More...
19 May 2014

Canada to Establish “Big Data” Cloud-Computing Facility for Cancer Research

The Government of Canada announced CAD 7.3 million in funding for a collaboration—both in Canada and internationally—to develop tools that can effectively manipulate huge amounts of data to help find cures for cancer.   More...
19 May 2014
Image: Graphic of the malaria parasite Plasmodium in a red
blood cell (Photo courtesy of Simon Levey).

Novel Technique Allows Genome Sequencing of Single Malaria Cells

  More...
18 May 2014

Bioinformatics Application Designed to Look for New Uses for Old Drug

By tying together cancer gene expression patterns with drug activity, scientists have found a possible cancer therapy concealed within an antimicrobial agent.   More...
18 May 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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