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BioResearch

Image: A mouse mammary gland missing the tumor-suppressor p53 shows expression of ARF (green), now known for a backup role in protecting cells from becoming cancerous. If both p53 and ARF are mutated, the tumors that form are aggressive and may benefit from treatment with anti-inflammatory drugs called JAK inhibitors, currently prescribed for rheumatoid arthritis (Photo courtesy of Raleigh Kladney).

Anti-Inflammatory Drugs May Treat Some Aggressive Tumors

New research raises the possibility that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs used to treat rheumatoid arthritis.  More...
10 Jul 2014
Image: A microscope image of a neuron with inclusion (stained orange) caused by Huntington\'s disease (Photo courtesy of Wikimedia Commons).

Molecular Interactions Identified That Block Protein Transfer into Mitochondria of Huntington's Disease Neurons

Researchers have identified a protein complex that interacts with the mutated form of huntingtin protein to impair transport of proteins into the mitochondria of brain cells, which leads to their malfunction and the loss of neurons that characterizes Huntington's disease.  More...
08 Jul 2014
Image: Dutch process cocoa (left) compared to natural cocoa (right) (Photo courtesy of Wikimedia Commons).

Polyphenol-Rich Cocoa Extracts Protect Against Alzheimer's Disease

A recent paper suggested that flavonol-rich cocoa extracts interfere with the processes that lead to the development of Alzheimer's disease.  More...
08 Jul 2014
Image: Mouse fibroblast shows Clec16a (red), the lysosome protein Lamp1 (green), the autophagosome protein LC3 (blue), and DNA (gray). The yellow overlap of the red and green stains shows that Clec16a resides in the endolysosomal compartment, part of the cellular disposal system used in mitophagy (Photo courtesy of the University of Pennsylvania).

Diabetes Linked to Faulty Mitochondria Disposal Pathway

A molecular pathway that regulates the disposal of defective mitochondria has been cited as a potential target for prevention and control of diabetes and certain other diseases.  More...
08 Jul 2014
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Automated Sample and Liquid Handling Platforms Suited for All Lab Sizes

Biotech and other life scientists who work with cell-based assays now have available a new line of advanced automated sample and liquid handling platforms.  More...
08 Jul 2014

Vaccine Being Developed for Heart Disease Close to Reality

The world’s first vaccine for heart disease is becoming a possibility with researchers demonstrating significant arterial plaque reduction in concept testing in mice.  More...
08 Jul 2014
Image: A structural model of the beta2 adrenergic receptor-arrestin signaling complex as deduced by electron microscopy, cross-linking, and mass spectrometry (Photo courtesy of Duke University).

Advanced Electron Microscopy Reveals Fine Structure of Active Signaling Complexes

A team of molecular biologists used advanced electron microscopy and mass spectroscopy techniques to determine the structure of the functional human beta2AR-beta-arrestin-1 signaling complex.  More...
07 Jul 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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