We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Vicotex

Download Mobile App




New Larger Volume Extraction System Increases Productivity and Sensitivity

By LabMedica International staff writers
Posted on 30 Jun 2014
Biotechnology and other life science researchers now have available an extraction system for larger volumes that prepares samples of up to one milliliter for LC-MS/MS (liquid chromatography-mass spectroscopy) or GC-MS (gas chromatography-mass spectroscopy) analysis.

The Biotage (Uppsala, Sweden) ISOLUTE SLE+ One Milliliter Supported Liquid Extraction 48-well plate system enables the extraction of larger sample volumes (one milliliter total load volume) than is presently possible in the standard microplate format.

The new format tubes are packed with ISOLUTE SLE+ material, with each well containing sufficient ISOLUTE SLE+ material to efficiently extract one milliliter of aqueous sample. More...
This is an alternative to the existing 96-well formats, which have a maximum capacity of 400 microliters. Larger sample volumes enable the researcher to generate higher sensitivity, higher throughput, and lower detection limits.

The ISOLUTE SLE+ plate is arranged in a six by eight array; with 48 samples being processed per plate. A new compatible 48-well collection plate is also available with a five milliliter capacity so that the entire elution solvent volume can be collected with no need to swap collection vessels.

The plates can be processed using microplate compatible positive pressure manifolds such as the Biotage Pressure+ 96, vacuum manifolds such as the Biotage VacMaster 96, and most automated liquid handling systems.

ISOLUTE SLE+ plates are ideal for the extraction of small molecule drugs, metabolites, and endogenous biomarkers from biological fluid samples prior to analytical techniques such as LC-MS/MS and GC-MS.

Related Links:

Biotage 



Platinum Member
Automated Coagulation Analyzer
Hemolumi H6
Gold Member
Automatic Hematology Analyzer
CF9600
Steam Sterilizer
Hi Vac II Line
New
Gold Member
Platelet Function Analyzer
PL-12
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Clinical Chemistry

view channel
Image: Graphical abstract (Pola, I., Akinyemi, T., Tan, K. et al. Nature Communications(2026). https://doi.org/10.1038/s41467-026-74971-4)

Blood Biomarker Study Reveals Population-Specific Differences in Alzheimer’s Disease

Blood-based biomarkers are emerging as tools for detecting Alzheimer’s disease–related changes without relying on advanced brain imaging or cerebrospinal fluid (CSF) analysis. However, much of the foundational... Read more

Molecular Diagnostics

view channel
Image Credit: Shutterstock

Blood Test for Lung Cancer Screening Receives FDA Breakthrough Device Designation

Lung cancer remains the leading cause of cancer death in the United States, yet only about 18% of people eligible for screening undergo low-dose computed tomography, the current guideline-recommended method.... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.