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BioResearch

European Biotech Agreement to Promote Antigen-Drug Conjugation Technology

Two European biotech companies have joined forces to exploit and commercialize an innovative, site-specific ADC (antigen-drug conjugate) conjugation technology. More...
02 May 2016

Biopharmaceutical Partnership Set to Advance Development of Therapeutic Antibodies

The development of therapeutic antibodies for the treatment of cancer and other chronic diseases is expected to be hastened by a recently announce collaborative agreement. More...
02 May 2016
Image: A confocal microscopy image of stem cells loaded with drug containing polymeric microparticles (Photo courtesy of Jeff Karp and Oren Levy, Brigham and Women\'s Hospital).

Cells Loaded with Prodrug-Containing Microparticles Selectively Destroy Prostate Cancer Tumors

A novel approach to treating metastatic prostate cancer with minimal adverse side effects is based on cellular transport of a harmless prodrug that is activated and becomes toxic only in the vicinity of the tumor microenvironment. More...
02 May 2016
Image: A space-filling model of the anticonvulsant drug carbamazepine (Photo courtesy of Wikimedia Commons).

Wastewater May Contaminate Crops with Potentially Dangerous Pharmaceuticals

Reclaimed wastewater used to irrigate crops is contaminated with pharmaceutical residues that can be detected in the urine of those who consumed such produce. More...
29 Apr 2016
Image: A confocal microscopy image of human fibroblasts derived from embryonic stem cells. The nuclei appear in blue, while smaller and more numerous mitochondria appear in red (Photo courtesy of Dr. Shoukhrat Mitalipov, Oregon Health & Science University).

Stem Cells Derived from Older Individuals May Carry Unsafe Mitochondrial DNA Mutations

Induced pluripotent stem cells (iPSCs) derived from the skin fibroblasts of older individuals have a likelihood of harboring mitochondrial DNA mutations, which may render them unfit for clinical applications. More...
29 Apr 2016
Image: A cross-section of injured mouse muscle tissue, with healthy tissue in pink and scar tissue shown in purple. Both mice genetically lack T-cells; the mouse on the left was injected with T-cells that became type II helper T-cells and aided healing (Photo courtesy of Dr. Kenneth Estrellas, Johns Hopkins University).

Biomaterial Scaffolds Boost Interleukin Production to Promote Wound Healing

The improved wound healing promoted by use of "biomaterial" scaffolds was shown to be due to activation of the immune system's T helper II pathway with a subsequent increase in production of interleukins. More...
29 Apr 2016
Image: Drop-inoculation of Saccharomyces cerevisiae mutants on an agar plate. The assay compares the viability of different yeast mutants (Photo courtesy of Wikimedia Commons).

Defective Genome Instability Suppressing Genes May Cause Some Types of Cancer

Cancer researchers reported in a recent study that defects in the expression of genes that suppress gross chromosomal rearrangements (GCRs) were linked to more than 93% of the ovarian and 66% of the colorectal cancer cases they had examined. More...
28 Apr 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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