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BioResearch

Mitochondrial Genomes Reconstructed from Teeth of Prehistoric Native Americans

Physicial anthropologists succeeded to enrich human mitochondrial DNA from dental calculus in amounts that enabled reconstruction of whole mitogenomes for maternal lineage ancestry analysis. More...
04 Apr 2016
Image: Overview of the design of synonymous tuf gene alleles. The first 40 codons were left unchanged (hatched region). Black bars represent codons changed to synonymous codons. (A) Wild-type gene, tufA; (B) through (G) Mutated versions of tuf gene (Photo courtesy of Brandis Hughes, 2016, and PLoS Genetics).

Evolutionary Fitness for Codon Bias Selection Measured

Using bacteria as a model, researchers have for the first time quantified weak but effective selection forces that determine non-random codon usage in protein translation of RNA.  More...
04 Apr 2016

Link Found Between Brain Metabolism and Fluid Intelligence

By measuring a metabolic activity marker using magnetic resonance spectroscopy, a new study in young adults has indicated that healthy brain metabolism corresponds with fluid intelligence, a measure of one’s ability to solve unusual or complex problems.  More...
03 Apr 2016
Image: Schematic representation of implant for passive immunization by long-term therapeutic antibody delivery. Cells genetically engineered to produce a therapeutic antibody are confined in a macroencapsulation “flat sheet” device and implanted in the subcutaneous tissue for in vivo antibody secretion into the bloodstream. Antibodies reaching the brain target, clear, and prevent the harmful amyloid-beta protein plaques of Alzheimer’s disease (Photo courtesy of Lathuilière A et al, 2016, and Swiss Federal Institute of Technology in Lausanne).

Medical Implant Device Reduces Alzheimer’s Pathology and Provides Passive Immunization

In landmark proof-of-concept study with mice, a cutting-edge subcutaneous-implant capsule developed for treatment for Alzheimer’s disease, successfully directed the immune system against the disease.  More...
03 Apr 2016

Portal Launched to Accelerate and Improve Biomedical Research Funding

A new website launched in collaboration with the National Institutes of Health will provide new funding opportunities for scientific projects and present an alternative option to the traditional government grant mechanisms.  More...
03 Apr 2016
Image: Structural model of the PAK1 protein (Photo courtesy of Wikimedia Commons).

Liposome Transport Protects Metabolic Activity of Prostate Cancer Drug

The efficacy of liposome transport to protect the physiological activity of a small-molecule anti-prostate cancer drug was demonstrated both in vitro and in a mouse xenograft model.  More...
30 Mar 2016
Image: Micrograph of a cell carrying an RNA-targeted Cas9 system that reveals beta-actin mRNA distribution in the cytoplasm (Photo courtesy of the University of California, San Diego).

Advanced Gene Editing Technology Enables RNA Tracking in Living Cells

Genomics researchers have used a modified version of the CRISPR/Cas9 gene editing technique to track the movement of RNA in living cells.  More...
30 Mar 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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