We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
PURITAN MEDICAL

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

World's First Fully Integrated Platform for Automated High Molecular Weight DNA Extraction

By LabMedica International staff writers
Posted on 23 May 2023
Print article
Image: The world`s first fully integrated platform for automated high molecular weight DNA extraction (Photo courtesy of One BioMed)
Image: The world`s first fully integrated platform for automated high molecular weight DNA extraction (Photo courtesy of One BioMed)

Long-read sequencing, a third-generation technology, throws light on certain "blind spots" that short-read sequencing methods cannot detect, such as complex structural variants. However, isolating high-quality, high molecular weight (HMW) DNA, which is crucial for long-read sequencing, can be a formidable task. The majority of commercial extraction methods compromise the quality and length of the extracted DNA due to mechanical processes like centrifugation or vortexing, as well as alcohol precipitation. These methods tend to be labor-intensive. Now, a novel technology is revolutionizing nucleic acid extraction with a gentle, yet rapid chemistry-based method that selectively binds, gently clusters, and purifies intact DNA using controlled fluidics. This unique workflow is also non-volatile and does not require ethanol, ensuring convenient shipping and room-temperature storage.

One BioMed (Singapore) has launched the X8 HMW DNA Cartridge Kits for automated extraction of HMW DNA, specifically designed for long-read sequencing and genome assembly. The X8 HMW DNA Cartridge Kits, driven by the OneTouch Instrument, present the first globally automated platform for HMW DNA extraction from an array of samples including bacteria, plants, cell culture, tissue, and Peripheral Blood Mononuclear Cells (PBMCs). The kits contain all necessary reagents.

The Xceler8 Platform guarantees consistent and reproducible extraction of HMW DNA up to 2 Mb range from diverse sample types across different users. The purified HMW DNA is fit for a variety of downstream applications including long-read sequencing and de novo genome assembly. Thanks to the flexibility of random access, the Xceler8 Solution can run multiple protocols at the same time and efficiently process up to 8 samples within an hour. This fully integrated, plug-and-play automation system is perfect for labs seeking a highly flexible and consistent method of HMW DNA extraction from a wide variety of sample types.

"We are excited to launch the new X8 HMW DNA Cartridge Kit." said Dr.Mi Kyoung Park, Founder & CEO of One BioMed. "This Kit extends the workflow and performance advantages of the novel Xceler8 Technology, enabling scientists to efficiently extract HMW DNA from a variety of samples, for various downstream applications."

Related Links:
One BioMed 

HLX
Gold Supplier
STI Real-Time PCR Test
Neisseria Gonorrhoeae/Chlamydia Trachomatis/U.urealyticum Real-Time PCR Kit
New
Spectrophotometer
UVILINE 9300
New
POCT Fluorescent Immunoassay Analyzer
FIA Go

Print article

Channels

Clinical Chem.

view channel
Image: Electrochemical cells etched by laser on wooden tongue depressor measure glucose and nitrite in saliva (Photo courtesy of Analytical Chemistry)

Biosensor-Fabricated Wooden Tongue Depressor Measures Glucose and Nitrite in Saliva

Physicians often use tongue depressors to examine a patient's mouth and throat. However, it is hard to imagine that this simple wooden tool could actively assess a patient's health. This idea has led to... Read more

Hematology

view channel
Image: The Atellica HEMA 570 and 580 hematology analyzers remove workflow barriers (Photo courtesy of Siemens)

Next-Gen Hematology Analyzers Eliminate Workflow Roadblocks and Achieve Fast Throughput

Hematology testing is a critical aspect of patient care, utilized to establish a patient's health baseline, track treatment progress, or guide timely modifications to care. However, increasing constraints... Read more

Immunology

view channel
Image: Newly observed anti-FSP antibodies have also been found to predict immune-related adverse events (Photo courtesy of Calviri)

First Blood-Based Biomarkers Test to Predict Treatment Response in Cancer Patients

Every year worldwide, lung cancer afflicts over two million individuals and almost the same number of people succumb to the disease. This malignancy leads the charts in cancer-related mortalities, with... Read more

Microbiology

view channel
Image: The rapid MTB strip test for tuberculosis can identify TB patients within two hours (Photo courtesy of Chulalongkorn University)

Rapid MTB Strip Test Detects Tuberculosis in Less Than an Hour without Special Tools

Tuberculosis (TB), a highly infectious disease, continues to pose significant challenges to public health worldwide. TB is caused by a bacterium known as "Mycobacterium tuberculosis," spreading through... Read more

Pathology

view channel
Image: The UNIQO 160 (CE-IVDR) advances diagnostic analysis for autoimmune diseases (Photo courtesy of EUROIMMUN)

Novel Automated IIFT System Enables Cutting-Edge Diagnostic Analysis

A newly-launched automated indirect immunofluorescence test (IIFT) system for autoimmune disease diagnostics offers an all-in-one solution to enhance the efficiency of the complete IIFT process, comprising... Read more

Technology

view channel
Electronic biosensor uses DNA aptamers for detecting biomarkers in whole blood samples (Photo courtesy of Freepik)

Electronic Biosensor Detects Biomarkers in Whole Blood Samples without Addition of Reagents

The absence of robust, reliable, and user-friendly bioanalytical tools for early and timely diagnosis of cardiovascular diseases, particularly sudden cardiac arrest, leads to preventable deaths and imposes... Read more

Industry

view channel
Image: The global hemostasis diagnostics market is expected to reach USD 3.95 billion by 2025 (Photo courtesy of Freepik)

Global Hemostasis Diagnostics Market Driven by Increase in Invasive Surgical Procedures

Injury or surgery naturally creates bleeding in living beings, which must be stopped to prevent excessive blood loss. The human body implements a protective mechanism known as hemostasis to stop excessive bleeding.... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.