New Tool for siRNA-Induced Gene Silencing

The efficient transfer of small interfering RNAs (siRNAs) into cells has so far been restricted to only a few easy-to-transfect cell lines. Now, new Nucleofector technology, enables the delivery of siRNA oligonucleotides into primary cells and hard-to-transfect cell lines. Cell-type specific Nucleofector kits can be used with both siRNA oligonucleotides and siRNA vectors in combination with the Nucleofector device.

The technology was developed by Amaxa (Cologne, Germany), a company focused on enhancing the speed and quality of pharmaceutical development and basic research in gene transfer and gene-based medicine. Amaxa said its Nucleofector technology is the first efficient nonviral method for gene transfer directly into the nucleus of primary cells and cell lines.

"We are delighted with the high demand for our technology in the field of siRNA applications. We expect siRNA to be among the segments with very high growth potential for Amaxa in the years to come,” said Rainer Christine, CEO of Amaxa.




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