We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App




Development Fund to Boost Search for Drugs to Modulate Nuclear Hormone Receptors

By LabMedica International staff writers
Posted on 09 Aug 2011
A project to develop novel small molecule retinoic acid related orphan receptor (ROR) modulators that target TH17 T-lymphocytes for the treatment of various autoimmune disorders including rheumatoid arthritis, multiple sclerosis, psoriasis, and COPD (chronic obstructive pulmonary disease) will be funded by a consortium of private investors.

The beneficiary of the development fund, Visionary Pharmaceuticals (San Diego, CA, USA), has created “BindingSIGHTs”, a proprietary computational technology platform, which encompasses an advanced suite of structural biology and chemical informatic tools. More...
BindingSIGHTs enables sophisticated virtual screening and structure-based drug design for challenging molecular drug targets. In addition, the company has created the “MANIFOLD” virtual compound library of more than 22 million compounds, which have been screened against ROR BindingSIGHTs fingerprints.

These tools are part of an innovative drug discovery engine that was created to focus on nuclear hormone receptors. Nuclear hormone receptor modulators represent 15% of all drugs approved in the United States and account for more than $27 billion in annual sales.

“Our BindingSIGHTs technology and MANIFOLD library enables us to save both time and money in generating the best possible lead series. With the initial seed round investments we are now able to launch full-scale research activities in our state-of-the-art labs,” said Dr. Gordon Alton, president and CEO of Visionary Pharmaceuticals. “We have assembled a veteran leadership team with proven expertise in driving novel therapies to IND (investigational new drug). Additionally, our Board of Directors and Scientific Advisory Board bring us a depth of industry experience in successfully driving high quality drug discovery and development programs and delivering high-value exits. Collectively this experience has resulted in more than a dozen novel drugs either marketed or in clinical trials.”

Related Links:

Visionary Pharmaceuticals




New
Gold Member
Aspiration System
VACUSAFE
POC Helicobacter Pylori Test Kit
Hepy Urease Test
New
Food Allergy Screening ELISA Kit
Allerquant 14G B ELISA
New
Clinical Informatics Platform
CLARION™
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Immunology

view channel
Image: Mycobacterium tuberculosis bacteria seen with a scanning electron microscope (Credit: CDC PHIL)

Antibody Blood Test Identifies Active TB and Distinguishes Latent Infection

Active tuberculosis (TB) remains a leading cause of death and illness worldwide, yet distinguishing contagious disease from latent infection continues to challenge clinicians. Standard screening tools... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.