We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Sekisui Diagnostics

Download Mobile App




Universal HPLC Detector Offers Near Nanogram Sensitivity

By LabMedica International staff writers
Posted on 09 Jun 2010
An ultra-sensitive, universal nano-quantity analyte detector (NQAD) presents a major advancement in high-performance liquid chromatography (HPLC) detection capability.

The NQAD nano-quantity analyte detector is a new and completely different kind of aerosol-based detector for HPLC. More...
Based on condensation nucleation (CNLSD) technology, the NQAD offers the ability to detect sub-nanogram levels. Benefiting from ultra-high sensitivity, the detector is suitable for searching for drug impurities, degradation products, excipients, and when industrial hygiene is a concern. Both previously easy and hard-to-measure compounds can be quantified accurately with minimal sample preparation.

The NQAD detector also offers a wide dynamic range with superior linearity when compared to other aerosol-based detectors. The detection of the NQAD detector is near universal for compounds that are less volatile than the mobile phase. Chromophores and fluorophores are not needed for detection, thereby eliminating or decreasing the need for compound derivatization. The detector is optimized for use in ultra high performance liquid chromatography (UHPLC), HPLC, and supercritical-fluid chromatography (SFC). Easy to install and operate, with one of the smallest footprints available the NQAD is suitable for use in any laboratory.

The detector was developed by Dorton Analytical (Thames, Oxfordshire, UK).

Related Links:

Available from Dorton Analytical




Platinum Member
Automated Coagulation Analyzer
Hemolumi H6
Gold Member
Automatic Hematology Analyzer
CF9600
Gold Member
Platelet Function Analyzer
PL-12
Platinum Member
Integrated Biochemical & Immunological System
Biolumi CX Solution X10+C10
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Clinical Chemistry

view channel
Image Credit: 123RF

Screening After Pneumococcal Disease May Reveal Undiagnosed Blood Cancer or Immune Disorders

Severe pneumococcal disease requiring hospitalization often presents as pneumonia, particularly in older adults and people with cancer or compromised immune function. Because M protein testing and antibody... Read more

Microbiology

view channel
Image Credit: 123RF

FDA-Cleared Multiplex PCR Test Detects 13 Respiratory Pathogens in a Single Sample

Respiratory tract infections can be difficult to distinguish at presentation because many cause overlapping, nonspecific symptoms and are initially grouped as influenza-like illnesses. Causes span a range... Read more

Technology

view channel
Image: The laser-based photoacoustic spectroscopy setup consists of a Mid-IR laser equipped with three QCL modules covering wavelengths from 5.6 μm to 12.9 μm, two silver coated mirrors (SCM), a dichroic mirror (DM) with a transmittance of 90%, a thermal power sensor head (PM) to monitor the output laser power, a mechanical chopper (MC) for frequency modulation and a CEPAS-detector with a self-designed swab holder (SH). (Credit: Graunke, T., Scholz, T., Pieniak, M. et al. Scientific Reports (2026). https://doi.org/10.1038/s41598-026-68298-9)

Laser-Based Swab Analysis Shows Promise for Detecting Disease-Linked Odor Patterns

Disease-related changes in volatile organic compounds can alter body odor, producing measurable patterns in exhaled breath and bodily fluids. Current analytical methods can be complex, time-consuming,... Read more

Industry

view channel
Image

Collaboration Combines AI Cognitive Assessment and RNA Blood Testing for Earlier Alzheimer’s Detection

Alzheimer’s disease is often identified only after substantial neurodegeneration, partly because current diagnostic pathways are fragmented and difficult to scale. As treatment shifts toward earlier intervention,... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.