We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Werfen

Download Mobile App




Lorenzo's Oil Prevents Pediatric Disorder

By Biotechdaily staff writers
Posted on 27 Jul 2005
A new study has shown that use of a treatment known as Lorenzo's Oil may prevent a pediatric disorder called x-linked adrenoleukodystrophy (X-ALD) from developing in young boys diagnosed with the disorder but not yet showing signs of it.

The study involved 89 boys, aged seven and younger, who tested positive for an abnormal gene that identifies X-ALD. More...
Over a period of seven years, researchers treated the boys with daily oral doses of Lorenzo's Oil, a combination of two fats extracted from olive oil and rapeseed oil, and moderately restricted their dietary fat. All patients had a normal brain scan and showed no neurologic signs and symptoms of X-ALD prior to the study. At the completion of the study, 74% of the 89 patients showed no signs of disease progression. The researchers correlated greater compliance with a lower risk of developing the disease. This is the first time that the preventive effects of Lorenzo's Oil have been demonstrated by rigorous and scientifically accepted research methods.

X-ALD causes the breakdown of myelin, a fatty substance that acts as an insulator around nerve fibers. Symptoms appear between ages four and 10, and can lead to nerve deterioration, loss of verbal communication, and eventually to complete breakdown of body function.

"This finding is an exciting progression of the research to which my associates and I have dedicated ourselves to help these children,” observed lead author Hugo Moser, M.D., director of the Neurogenetics Research Center at the Kennedy Krieger Institute (Baltimore, MD, USA).

There is still no cure for X-ALD, and treatment options are limited to hormone therapy and bone marrow transplants. Lorenzo's Oil was invented by Augusto and Michaela Odone, whose son, Lorenzo, was diagnosed with X-ALD. Although the oil cannot repair damage already done, it can prevent the disease from progressing into a degenerative state. In spite of the fact that Lorenzo already showed symptoms before taking the oil, the treatment stopped the progression of his disease, and he celebrated his 27th birthday in May 2005. The story of the Odone family's struggle was dramatized in the 1992 motion picture entitled "Lorenzo's Oil.”





Related Links:
Kennedy Krieger Institute

Gold Member
Hematology Analyzer
Medonic M32B
POC Helicobacter Pylori Test Kit
Hepy Urease Test
Automatic CLIA Analyzer
Shine i9000
ESR Analyzer
TEST1 2.0
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to LabMedica.com and get access to news and events that shape the world of Clinical Laboratory Medicine.
  • Free digital version edition of LabMedica International sent by email on regular basis
  • Free print version of LabMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of LabMedica International in digital format
  • Free LabMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Molecular Diagnostics

view channel
Image: LIAISON Murex Anti-HDV Immunoassay is the first fully automated FDA-authorized immunoassay for HDV detection in the U.S. (Photo courtesy of Diasorin)

Fully Automated Immunoassay Test Detects HDV Co‑Infection and Super-Infection

Hepatitis delta, also known as hepatitis D, is caused by the hepatitis delta virus (HDV). It is a viral liver infection that can result in one of the most severe forms of viral hepatitis.... Read more

Immunology

view channel
Image: Circulating tumor cells isolated from blood samples could help guide immunotherapy decisions (Photo courtesy of Shutterstock)

Blood Test Identifies Lung Cancer Patients Who Can Benefit from Immunotherapy Drug

Small cell lung cancer (SCLC) is an aggressive disease with limited treatment options, and even newly approved immunotherapies do not benefit all patients. While immunotherapy can extend survival for some,... Read more

Microbiology

view channel
Image: New evidence suggests that imbalances in the gut microbiome may contribute to the onset and progression of MCI and Alzheimer’s disease (Photo courtesy of Adobe Stock)

Comprehensive Review Identifies Gut Microbiome Signatures Associated With Alzheimer’s Disease

Alzheimer’s disease affects approximately 6.7 million people in the United States and nearly 50 million worldwide, yet early cognitive decline remains difficult to characterize. Increasing evidence suggests... Read more

Technology

view channel
Image: Vitestro has shared a detailed visual explanation of its Autonomous Robotic Phlebotomy Device (photo courtesy of Vitestro)

Robotic Technology Unveiled for Automated Diagnostic Blood Draws

Routine diagnostic blood collection is a high‑volume task that can strain staffing and introduce human‑dependent variability, with downstream implications for sample quality and patient experience.... Read more

Industry

view channel
Image: Industry experts gather at WHX Labs Dubai to discuss how leadership must adapt as AI and automation transform the laboratory (Photo courtesy of Shutterstock)

WHX Labs in Dubai spotlights leadership skills shaping next-generation laboratories

WHX Labs in Dubai (formerly Medlab Middle East), held at Dubai World Trade Centre (DWTC) from 10–13 February, brings together international experts to discuss the factors redefining laboratory leadership,... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.