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Pathology

New Approach Identifies Multiple Melanoma Drug Resistance Biomarkers

A recent paper described the use of liquid chromatography-multiple reaction monitoring mass spectrometry for assessing melanoma biomarkers in the blood in order to determine the effectiveness of chemotherapy.  More...
14 Jul 2014
Image: The Cytosponge, a non-endoscopic test for collecting cells from the esophagus, in gelatin capsule (right) and expanded (left) (Photo courtesy of Cambridge Cancer Center).

Genetic Test Improves Prognosis for Esophageal Cancer

The genetic basis of why some people with a serious complication of acid reflux known as Barrett's esophagus go on to develop esophageal cancer has been determined.   More...
13 Jul 2014
Image: Illumina’s Infinium Human Methylation BeadChip Kits (Photo Courtesy of University of Munster).

Blood Test Developed to Indicate Breast Cancer Risk

A simple blood test to help predict the likelihood of a woman developing breast cancer has been developed, as the idea that genetic mutations are the sole contributors to the development of the disease is changing.  More...
10 Jul 2014
Image: Histology of squamous cell carcinoma of the bladder (Photo courtesy of British Columbia Cancer Agency).

Simple Urine Test Diagnoses Bladder Cancer Early

A highly-specialized urine test can detect bladder cancer as much as three to six months earlier than an invasive cystoscopy procedure and can help physicians diagnose the disease at an initial stage, when treatment might be more effective.   More...
03 Jul 2014
Image: Histopathology of a kidney showing membranous glomerulonephritis (Photo courtesy of University of Utah).

Noninvasive Test Helps Identify Cause of Specific Kidney Disease

The first test that can help determine a specific type of kidney disease, called membranous glomerulonephritis has been authorized for marketing.  More...
02 Jul 2014
Image: The heart biopsy procedure is most often done by inserting the biopsy instrument (bioptome) through a small incision in the skin on the right side of the neck. Four or five separate pieces of tissue are needed for adequate sampling (Photo courtesy of Stanford Hospital).

Blood-Based DNA Test May Replace Heart Biopsy for Detecting Transplant Rejection

In a proof-of-principle study, a noninvasive DNA-based blood test was found to be more accurate than the standard heart biopsy procedure for detecting heart transplant rejection.  More...
01 Jul 2014
Image: Human bone marrow derived mesenchymal stem cell after three weeks of culture showing fibroblast like morphology seen under phase contrast microscope at 63x magnification (Photo courtesy of Wikimedia Commons).

Leptin Receptor Identified a Mesenchymal Stromal Cell Biomarker

The Leptin Receptor has been identified as a biomarker for the progenitor cells that are the major source of bone and adipocytes in adult bone marrow.  More...
30 Jun 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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