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Pathology

Image: The gas chromatography sensor system, Odoreader, is used for the diagnosis of urological malignancies (Photo courtesy of the University of Liverpool).

Urine Diagnostic Test Created for Urological Malignancies

A urine diagnostic test has been created for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.  More...
21 Feb 2016
Image: Staining with the monoclonal antibody TAB-004 is so specific for most cases of mammary carcinoma, immunoreactivity in the tumor can be appreciated even without the microscope. OncoTAb’s blood test may be a useful supplemental test with mammography for women with dense breast tissue (Photo courtesy of OncoTab).

Blood Test Enables Earlier Detection of Breast Cancer

Extensive mammographic density may make breast cancer more difficult to detect by mammography and thus increases the risk of the development of cancer between mammographic screening tests.  More...
16 Feb 2016
Image: The ONCOblot two-dimensional gel electrophoresis and western blot test is already making a difference in the lives of patients (Photo courtesy of MorNuCo Inc.).

2D Gel Immunoblot Test Detects Mesothelioma Biomarkers in the Blood Years Prior to Appearance of Symptoms

An advanced two-dimensional gel electrophoresis test has demonstrated the presence of a biomarker for mesothelioma in the serum of individuals four to 10 years before the appearance of clinical symptoms.  More...
16 Feb 2016
Image: Section of a head and neck cancer biopsy was stained for p21 (brown) and for S6 phosphorylation (red). S6 phosphorylation depends directly on mTOR and, therefore, its detection is an indication of mTOR activity (Photo courtesy of Centro Nacional de Investigaciones Oncologicas).

Study Shows Importance of mTORC1 and p21 Signaling in Head and Neck Carcinomas

A team of Spanish cancer researchers has found that over-activation of the mTORC1/4E-BP1/p21 molecular pathway is a frequent and clinically relevant alteration in head and neck squamous cell carcinomas.  More...
15 Feb 2016
Image: Patients whose stage II colon cancer tested negative for CDX2 expression (left) had a worse prognosis than those whose cancer tested positive (right) (Photo courtesy of Columbia University Medical Center).

Prognostic Biomarker Found for Colon Cancer Patients

The majority of colon cancer patients whose tumors have started to travel to nearby tissue but no further are cured by surgery alone, but in a minority of these stage II colon cancer cases the cancer returns and the patients die.  More...
10 Feb 2016
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Aberrant Gene Expression Predicts Metastatic Endometrial and Lung Cancers

The spread of cancer cells from the initial site of occurrence, the primary site, to other secondary tissues is called metastasis, and contributes to poor or limited response of cancer cells to treatments, which results in death.  More...
10 Feb 2016
Image: The fecal immunochemical test (FIT) kit used in screening for colorectal cancer (Photo courtesy of Kaiser Permanente).

Fecal Immunochemical Test Effective for Annual Colon Cancer Screening

The fecal immunochemical test is highly sensitive for detecting colorectal cancer, and adherence to annual follow-up screening among initial participants is high, making the noninvasive test feasible and effective for annual colorectal cancer screening programs.  More...
10 Feb 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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