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Pathology

Image: An adult Opisthorchis viverrini or Southeast Asian liver fluke stained with carmine (Photo courtesy of the CDC).

Unsuspected Bacterial Link to Bile Duct Cancer Discovered

Bacteria in the bile duct have been identified as a potential risk factor in the development of bile duct cancer, or Cholangiocarcinoma, a rare but aggressive form of cancer with symptoms that do not present themselves at the early stages. More...
06 Jul 2016
Image: The NuQ biomarker assays capture and identify nucleosomes circulating in the blood of cancer patients (Photo courtesy of VolitionRx).

Circulating Cell-Free Nucleosomes Biomarkers Confirmed for Cancer Blood Tests

Studies have shown substantially improved overall survival among individuals screened for colorectal cancer (CRC), which is explained by diagnosis of early stages and prevention of CRC by endoscopic removal of precancerous lesions. More...
30 Jun 2016
Image: The therascreen EGFR RGQ PCR Kit is an automated molecular assay designed to detect the presence of mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC) (Photo courtesy of Qiagen).

Liquid Biopsy Urine Test Detects Mutations In Lung Cancer

While lung cancer is one of the most aggressive malignancies, progress has been made in the advancement of therapeutic strategies against the disease and in particular, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). More...
29 Jun 2016
Image: A micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. H&E stain. The dark purple (center) is lymphocytes (part of a normal lymph node). Surrounding the lymphocytes and extending into the surrounding fat (top of image) is ductal breast carcinoma (Photo courtesy of Michael Bonert / Wikimedia).

Artificial Intelligence Achieves Near-Human Performance in Image Analysis

A research team has developed an artificial intelligence (AI) method that trains computers to interpret pathology images. In a recent test of the method developed to examine images of lymph nodes, human complemented with computer analyses together identified breast cancer with 99.5% accuracy. More...
27 Jun 2016
Image: Neurons in the brain. Researchers have identified a DNA variant that appears to regulate levels of glutamate - a chemical, known as a neurotransmitter, which transports messages between neurons in the brain (Photo courtesy of Dr. Jonathan Clarke, Wellcome Images).

Wide-ranging Genomic Study Links Migraine-Related Genes to the Vascular System

Results from 22 genome-wide association (GWA) studies conducted by dozens of researchers worldwide suggest that migraine is linked to specific gene loci that are associated with some vascular disease or are involved in the regulation of vascular tone. More...
27 Jun 2016
Image: The MammaTyper in vitro diagnostic test kit for breast cancer subtyping (Photo courtesy of BioNTech Diagnostics).

PCR Better at Identifying Breast Tumor Subtypes than Immunohistochemistry

A recently published study suggested that a RT-qPCR (reverse transcription quantitative real-time polymerase chain reaction) assay was superior to classical immunohistochemistry for subtyping breast tumors. More...
27 Jun 2016
Image: The ImmunoSEQ kit for analyzing T- and B-cells (Photo courtesy of Adaptive Biotechnologies).

T-Cell Receptor Sequencing Reveals Novel Biomarkers For Ovarian Cancer

Deep T-cell receptor (TCR) sequencing has been used to evaluate the clonal composition of tumor-infiltrating lymphocytes and identify novel prognostic biomarkers in ovarian cancer. More...
22 Jun 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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