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Microbiology

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Vaginal Infection Increases Risk of Fetal Membrane Rupture

Preterm pre-labor rupture of the fetal membranes precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis.
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05 Feb 2018
Image: T regulatory cells (also known as Tregs or Regulatory T cells) are essential cells that suppress immune responses of other cells, designed to limit excessive reactions and prevent autoimmunity. Tregs are characterized by the expression of CD4+, CD25+,and Foxp3+, while lacking CD127 (Photo courtesy of BioLegend).

Cellular Mechanism Identified for Severe Viral Hepatitis

It is known that activated immune cells of patients with viral hepatitis destroy hepatocyte, but its regulatory mechanism has not yet been described. Regulatory T cells (Tregs) inhibit activation of other immune cells and thus are important for homeostasis of the immune system. More...
29 Jan 2018
Image: A representation of the portable device uMEDNA for DNA amplification and detection (Photo courtesy of Harvard University).

Handheld Device Developed for DNA Amplification and Detection

A method has been developed that combines electrochemical detection with recombinase polymerase amplification (RPA) on a portable device to improve detection of genetic material from multiple tuberculosis strains. More...
23 Jan 2018

Amplification Tests Evaluated for Pelvic Inflammatory Disease

Sexually transmitted Chlamydia trachomatis (chlamydia) is the most prevalent sexually transmitted infection (STI) with an estimated 68,455,000 incident cases globally in women in 2012. Chlamydia is the subject of intensive control efforts in many high-income settings. More...
23 Jan 2018
Image: Colonies of different species of Candida after growing for 48 hours at 37 °C in CHROMagar Candida medium supplemented with Pal\'s agar (Photo courtesy of the American Society of Microbiology).

Oral Yeasts from Cancer Patients Identified by MALDI-TOF

The most predominant yeasts isolated from oral colonization and infections are Candida species that are the most important opportunistic fungal pathogens in humans and cause mucosal to deep-seated candidiasis. Opportunistic infections due to Candida species occur frequently in cancer patients because of their inherent immunosuppression. More...
22 Jan 2018

Portable Olfactory Sensor Designed for Diagnosis of Bacteria

A portable electronic "nose" (eNose) has been designed to rapidly detect and identify the most common bacteria causing soft tissue infections. More...
22 Jan 2018
Image: A digitally colorized scanning electron microscopic (SEM) photograph depicting a single, red-colored H9-T-cell that had been infected by numerous, spheroid-shaped, mustard-colored human immunodeficiency virus (HIV) particles, which can be seen attached to the cell\'s surface membrane (Photo courtesy of the US National Institute of Allergy and Infectious Diseases).

Serum Albumin Level Predicts Serious HIV Events

Serum albumin may be used to stratify human immunodeficiency virus (HIV)–infected persons with a high CD4+ T-cell count according to their risk of serious non-Acquired Immune Deficiency Syndrome (AIDS) endpoints. More...
18 Jan 2018
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