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Immunology

Image: A new catalyst that improved the sensitivity of the standard PSA ELISA test by about 110-fold was made of palladium nanocubes coated with iridium (Photo courtesy of Dr. Xiaohu Xia, Michigan Technological University).

Peroxidase Mimic Outperforms Natural Horseradish Peroxidase in ELISA Test

A test-of-concept study demonstrated that a synthetic catalyst that mimics the action of horseradish peroxidase could increase the sensitivity of a colorimetric enzyme-linked immunosorbent assay for human prostate surface antigen by more than 110-fold.  More...
29 Sep 2015
Image: For five (1-5) diagnostic antibodies: specific-binding curves of Total IgY in a complex protein solution binding to immobilized antigen. Data provide direct information about the specificity of three different production batches, highly valuable information especially for development of diagnostic assays. Curves for all antigen spots are shown. Binding of IgY is observed only to its respective immobilized antigen. (Photo courtesy of Sanovo Biotech).

Avian Antibodies with an Edge of Quality

New chicken IgY antibodies with SPRi validation of specificity and affinity provide an advantage in choosing antibodies for research and for development of diagnostic tests.  More...
24 Sep 2015
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Saliva Test Identifies Healthy Older People with Cognitive Problems

The saliva of healthy older people should be tested for the level of the stress hormone cortisol and this may help identify individuals who should be screened for problems with thinking skills.  More...
15 Sep 2015
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Antibodies Provide Clues to Transplant Rejection Risk

The dominant antibody type present in the blood of transplant recipients may indicate their likelihood of experiencing organ rejection, and this may help doctors identify patients who need aggressive treatments to safeguard the health of their new organ.   More...
09 Sep 2015
Image: The AdexusDx hCG early pregnancy testing kit (Photo Courtesy of NOWDiagnostics).

Rapid Blood Test Allows for Earlier Detection of Pregnancy

Early detection of pregnancy is important for caregivers in order to avoid certain medications and procedures that could harm a fetus, but unfortunately, clinics are experiencing too many false-negative results from point-of-care urine-based tests.  More...
07 Sep 2015
Image: Immunochemistry of bone marrow biopsy from an acute myeloid leukemia patient showing sheets of CD34 positive cells; corresponding bone marrow aspirate showed only 20% blasts (Photo courtesy of All India Institute of Medical Sciences).

Immunohistochemistry Assesses Early Response in Acute Myeloid Leukemia

Acute myeloid leukemia is a heterogeneous disease with respect to prognosis and early response assessment has an established role as predictor of remission rate, and overall and disease-free survival.  More...
26 Aug 2015
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Serum Cytokine Levels Compared in Behçet's Disease

Behçet's disease is a chronic systemic inflammatory disorder, stands out from other autoimmune and auto-inflammatory diseases due to its unique properties and is characterized by recurrent episodes of oral and genital ulcers, uveitis, and various systems involvement.   More...
23 Aug 2015
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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