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Immunology

Image: The BN ProSpec system and nephelometer (Photo courtesy of Siemens Healthcare).

Inflammatory Markers Predict Risk of Morbidity and Mortality

Inflammatory markers are known to be associated with cancer, chronic heart disease and other serious health conditions; however, the marker that is most useful in predicting these diseases continues to be debated. More...
22 Dec 2016
Image: The nCounter Analysis System is a novel digital read-out technology that provides direct multiplexed measurement of gene expression with high levels of precision and sensitivity (Photo courtesy of NanoString Technologies).

Stem Cell-Based Test Predicts Leukemia Patients' Response to Therapy

A 17-gene signature derived from leukemia stem cells has been developed that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment. More...
22 Dec 2016
DIASOURCE (A Biovendor Company)
Image: The cobas e 411 fully automated, random access system for immunoassay analysis (Photo courtesy of Roche Diagnostics).

Performance of Second Generation Cortisol Assay Evaluated

Untreated disorders of the adrenocortical system, such as Cushing’s or Addison’s disease, can be fatal, and accurate quantification of a patient’s cortisol levels is vital for diagnosis. A straightforward diagnostic approach is of essential importance, and accurate quantification of cortisol levels plays a key role in the diagnosis of patients with suspected disease. More...
21 Dec 2016
Image: The Solana platform leverages the Helicase-Dependent Amplification (HDA) technology to generate fast and accurate test results (Photo courtesy of Quidel).

FDA Clears Assay for Herpes Simplex and Varicella-Zoster Viruses

The US Food and Drug Administration (FDA) has given 510(k) clearance for a new molecular assay for herpes simplex virus (HSV) types 1 & 2 and varicella-zoster virus (VZV), developed to run on the Solana platform. More...
20 Dec 2016
Image: Immunohistochemistry of transfected cells: antibodies against NMDAR and CASPR2 (top), AMPAR1 and LGI1 (middle), AMPAR2 und GABAB-R (bottom) (Photo courtesy of Euroimmun).

Multiparametric Serological Testing Aids Diagnosis of Autoimmune Encephalitis

Autoimmune encephalitides can manifest with diverse neurological symptoms, including memory deficits, neuropsychiatric conditions and epileptic seizures, and may or may not be associated with cancer. More...
09 Dec 2016
Image: A colored scanning electron micrograph (SEM) of two T lymphocyte cells attached to a cancer cell (Photo courtesy of the National Institute of Health).

Variations in T-cells Identifies Susceptibility to Disease

Different cells of the human body differ greatly in structure and function; however, variation exists even among cells of one type and it is now suggested that the magnitude of such differences in T lymphocytes, or T cells, may indicate an individual's age and genetic predisposition to disease. More...
09 Dec 2016
Image: Transmission electron microscopic (TEM) depicts numbers of cytomegalovirus (CMV) virions that were present in a tissue sample (Photo courtesy of Sylvia Whitfield).

Congenital Cytomegalovirus Infection Predicted in High-Risk Pregnant Women

Congenital cytomegalovirus (CMV) infection can cause serious complications such as hearing difficulties and mental delay in affected infants. A new method for predicting congenital CMV infection during the prenatal period has been discovered. This method is safe for both mothers and fetuses, and could potentially be adopted for general use. More...
08 Dec 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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