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Immunology

Image: The sciFLEXARRAYER system is an ultra-low volume dispensing systems (Photo courtesy of SCIENION).

Immunoassay Monitors Parasite Persistence in Chagas Disease

The Trypanosoma cruzi parasite is the causative agent of Chagas disease, and infects about six million individuals in more than 20 countries. Monitoring parasite persistence in infected individuals is of utmost importance to develop and evaluate treatments to control the disease. More...
01 Mar 2018
Image: Principle scheme of antibody detection by ADAP for HIV (Photo courtesy of Stanford University).

Novel Saliva-Based PCR Assay Detects HIV Antibodies Earlier

An oral fluid-based test for human immunodeficiency virus (HIV) shows promise as a population-based screening tool. According to its developers, the test is easier to collect than blood but yields results that are just as reliable. More...
28 Feb 2018
Image: The frequency and activity of conventional T cells serves as an early childhood immune signature that predicts the development of asthma later on. The iNKT cells are shown in green, lung vasculature in red and cell nuclei in blue (Photo courtesy of Dr. Catherine Crosby, La Jolla Institute for Allergy and Immunology).

Immune Signature Predicts Asthma Susceptibility

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. A subset of T cells has been identified whose frequency serves as early childhood immune signature that predicts the risk of developing asthma later on. More...
27 Feb 2018
Image: A cross-section of a healthy brain compared with a brain from a patient with Alzheimer’s disease (Photo courtesy of the Alzheimer’s Association).

Immune System Dysfunction May Occur Early in Alzheimer’s Disease

Inflammatory markers have been shown to predict neurocognitive outcomes in aging adults; however, the degree to which peripheral markers mirror the central nervous system remains unknown. More...
21 Feb 2018
Image: The FLUOstar Omega multi-mode microplate reader with six detection modes (Photo courtesy of BMG Labtech).

Molecular Test Adapted for Parkinson’s and DLB

Parkinson’s disease (PD), multiple system atrophy (MSA), dementia with Lewy bodies (DLB) (or Lewy body dementia) are called α-synucleinopathies due to the abnormal accumulation of aggregates of a protein called α-synuclein (αSyn) in the brain. More...
20 Feb 2018
Image: Immunohistochemistry of MLH-1 (M1) Mouse Monoclonal Primary Antibody which is used to qualitatively identify human DNA mismatch repair (MMR) protein MLH1, expressed in the nucleus of normal proliferating cells. Loss of MLH1 is associated with colorectal and other cancers (Photo courtesy of Roche Tissue Diagnostics).

Colorectal Cancer Immunohistochemistry Panel Launched

The global burden of colorectal cancer is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. Increasingly, guidelines are recommending universal screening of all newly diagnosed colorectal cancers for Lynch syndrome. More...
13 Feb 2018
Image: Depiction of circulating tumor cells detaching from a primary tumor and circulating through the bloodstream (Photo courtesy of CellMax Life).

CTC Blood Test Detects Early Stage Colorectal Cancer

Colorectal cancer is among the most preventable cancers when detected early. Yet, it is the second leading cancer killer in the USA. Traditional methods like colonoscopies and stool-based tests are invasive or inconvenient and compliance with colorectal cancer screening remains low, leading to most colorectal cancers being detected in late stages, when survival rates are poor. More...
13 Feb 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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