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Molecular Diagnostics

Image: BioCoat Matrigel Invasion Chambers (Photo courtesy of BD Bioscience).

Biomarker Improves Diagnosis of Esophageal Cancer

A biomarker has been discovered that has the potential to improve the diagnosis, prognosis, and treatment of Esophageal Squamous Cell Carcinoma, the major histological form of esophageal cancer, a leading cause of cancer death worldwide.    More...
23 Jan 2014
Image: The Gallios Flow cytometer (Photo courtesy of Beckman Coulter).

Biopsy Test Predicts Aggressive form of Skin Cancer

The genetic profile of immune cells next to a melanoma could lead to more accurate diagnosis to indicate whether a skin cancer is aggressive enough to metastasize.   More...
23 Jan 2014

MicroRNAs Predict Likelihood of Breast Cancer Metastasis

The discovery that breast cancer patients who experienced quick relapses tended to have low levels of the microRNA miR-21 and high levels of the microRNA miR-205 in their tumor tissues suggests that measurement of these two biomarkers could identify women at risk of metastasis.  More...
22 Jan 2014
Image: The Nanodrop 1000 Spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Blood Test Locates Gene Defects Linked to Cancer

A simple blood test could be developed to determine whether gene mutations associated with pancreatic cancer exist without the need of locating and testing tumor tissue.  More...
21 Jan 2014

Horizon and AstraZeneca Announce Oncology Agreement

Horizon Discovery and AstraZeneca have entered into research collaboration and license agreement to explore a range of oncology-relevant genotypes with the aim of identifying and validating a number of novel drug targets.  More...
21 Jan 2014
Image: TaqMan Reverse Transcription Kit for microRNA (Photo courtesy of Life technologies).

Blood-Based Biomarkers Validated for Mild Cognitive Impairment

A minimally invasive test is essential for the early detection and monitoring of Alzheimer's and other neurodegenerative diseases for both drug development and planning of patient care.  More...
20 Jan 2014

Determination of Circulating CPN Cleavage Peptides Enables Early Diagnosis of Breast Cancer

The concentration of circulating peptides produced by CPN cleavage reflects the CPN activity in tumors, and analysis of these biomarkers demonstrates potential for the noninvasive and early diagnosis of breast cancer.  More...
20 Jan 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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