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Pathology

Image: A programmable LED illumination source rapidly switches between bright-field and dark-field modes to acquire multimodal images. By integrating complementary information through a physics-guided deep neural network, the framework enables high-fidelity super-resolution reconstruction of low-resolution pathology images. (Prof. Qian Chen, Prof. Chao Zuo from Nanjing University of Science and Technology, and Prof. Juergen W. Czarske from TU Dresden Image source link: https://doi.org/10.29026/oea.2026.260060)

Hybrid Computational Imaging Method Improves Digital Pathology Resolution

An AI approach using hybrid bright–dark field imaging boosts WSI resolution 2.1× and raises cervical screening sensitivity 11%. More...
10 Sep 2026
Image: The FDA‑cleared NanoZoomer lineup now spans compact benchtop deployment with the S20MD, routine laboratory workflows with the S360MD, and high‑throughput laboratory operations with the S540MD (Photo courtesy of Hamamatsu Photonics K.K.)

FDA Clearance Expands Digital Pathology Options for Clinical Laboratories

A new pair of FDA-cleared slide scanners enables scalable digital pathology from benchtop to high-throughput clinical labs. More...
08 Sep 2026
Image: Metabolically quiescent (left) and activated (right) peripheral blood mononuclear cells captured with optical metabolic imaging. (Image Credit: Skala Lab / Jeremiah Riendeau)

Label-Free Imaging Reveals Hidden Immune Activity in Blood Samples

A label-free optical imaging approach detects immune cell activation within 2 hours. More...
03 Sep 2026
Image: Graphical Abstract (Vivek Behera et al., Pan-tumor spatial transcriptomics reveals conserved properties of tumor organization, Cell Reports Medicine, 2026. DOI: 10.1016/j.xcrm.2026.103013)

AI Tool Improves Prediction of Immunotherapy Response in Lung Cancer

An AI approach uses spatial gene-activity "floor plans" to predict immunotherapy response in lung cancer. More...
03 Sep 2026
Image Credit: Adobe Stock

New Journal Addresses Evolving Needs in Clinical and Translational Pathology

A new journal unites AI, spatial multi-omics, and molecular pathology to speed diagnosis and therapy selection. More...
01 Sep 2026
Image: Researchers evaluated AI models that quantify tumor-infiltrating lymphocytes (TIL) on routine breast tissue slides, where higher TIL levels reflect stronger antitumor response and improved breast cancer outcomes (Image Credit: Shutterstock)

AI Matches Pathologists in Predicting Breast Cancer Prognosis from Immune Cells

An AI approach quantifies tumor-infiltrating lymphocytes on breast cancer slides, matching pathologists to predict outcomes across major subtypes. More...
27 Aug 2026
Image: TRUECAM automatically eliminates ambiguous or uninformative regions in whole-slide pathology images, enhancing the reliability of diagnostic analysis. (Photo courtesy of PolyU)

AI-Pathologist Framework Improves Accuracy and Reliability in Cancer Diagnosis

An AI approach for whole-slide imaging boosts cancer subtyping accuracy and flags out-of-scope cases. More...
24 Aug 2026
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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