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Pathology

Multiplex immunofluorescent (left) and H&E-stained (right) breast tumor samples illustrating high versus low Base Topology Scores. Higher topology scores reflect more organized tissue architecture, while lower scores indicate greater structural disorganization. By quantitatively measuring these structural differences, the researchers developed biomarkers that predicted patient outcomes more accurately than many traditional approaches. (Photo courtesy of Columbia University Irving Medical Center)

Digital Pathology Tool Predicts Breast Cancer Outcomes and Therapy Response

A topology-based approach quantifies tumor architecture to improve breast cancer prognosis and predict therapy response. More...
22 Jul 2026
Image: Atypical clustering of myeloid progenitor cells called myeloblasts (white arrows), defined by their co-expression of CD34 (magenta) and CD117 (green), in a bone marrow biopsy tissue from a patient with MDS. (Image Credit: Dr. Sanjay Patel)

AI Bone Marrow Mapping Provides New Tool to Track Blood Cancer Severity

An AI approach measures disease severity from routine bone marrow images, improving classification and ongoing monitoring of MDS. More...
20 Jul 2026
Graphical Abstract  (Johann Dierks et al., Analytical Chemistry (2026). DOI: 10.1021/acs.analchem.5c07622)

Imaging Platform Maps Lipid Accumulations in Fabry Heart Tissue

A combined imaging method maps a Fabry-related molecule in heart tissue at very high resolution. More...
16 Jul 2026
Image credit: Adobe Stock

AI Tissue Imaging Helps Guide Targeted Therapy for Lung Cancer

An AI imaging approach predicts key lung cancer mutations from routine biopsy samples. More...
15 Jul 2026
Image: Graphical Abstract (Yang Liu et al,. Cancer Cell (2026). DOI: 10.1016/j.ccell.2026.06.009)

Tissue-Based Gene Signature Signals Colorectal Cancer Recurrence Risk

A new tissue-based six-gene signature in CRC liver micrometastases signals MRD, recurrence risk, and chemotherapy resistance. More...
15 Jul 2026
Image Credit: Shutterstock

FDA-Approved Companion Diagnostic Detects PTEN Loss in Prostate Cancer

NeoGenomics has launched the first IHC companion diagnostic test approved by the U.S. FDA for patients with prostate adenocarcinoma.  More...
13 Jul 2026
Image: Overview of the self-supervised learning method DINOv2 applied to digital pathology. (Witowski, J., Zeng, K.G., Cappadona, J. et al. Nature Communication, 2026. https://doi.org/10.1038/s41467-026-73088-y)

New AI Test Delivers Rapid Breast Cancer Recurrence Predictions

An AI test estimates breast cancer recurrence risk from routine slides and data, matching genomic assays and enabling faster care. More...
09 Jul 2026
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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