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Clinical Chemistry

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Blood Protein May Help Identify Treatment-Resistant Psychosis

New findings identify a potential blood biomarker for treatment-resistant psychosis that could help guide treatment decisions. More...
14 Oct 2026
Image: Schematic illustration of the operating principle of the enzyme-reaction-based highly sensitive biosensor (ESGNS) (Credit: Chihyun Kim, Wonjun Jo, Dayoung Chang, et al. Enzymatic sialylation–driven gold nanostructured platform for rapid and selective detection of sialic acid–deficient transferrin. Chemical Engineering Journal, 2026. https://doi.org/10.1016/j.cej.2026.182244)

Electrochemical Biosensor Rapidly Detects Cerebrospinal Fluid Leaks

A new electrochemical biosensor rapidly detects a cerebrospinal fluid marker to confirm leaks, supporting point-of-care testing More...
14 Oct 2026
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Blood Protein Panel Supports Monitoring of Treated Celiac Disease

Targeted serum proteomics identifies protein patterns tracking celiac activity and intestinal damage on a gluten-free diet. More...
13 Oct 2026
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Hemoglobin Levels May Help Signal Long-Term Dementia Risk

Researchers identify abnormal hemoglobin as a marker for increased long-term dementia risk from routine blood tests. More...
12 Oct 2026
Image: The test is designed to detect ovarian cancer early in symptomatic women, addressing a critical diagnostic gap in a cancer associated with high mortality. (Image Credit: iStock)

Liquid Biopsy Platform Shows Promise for Early Gynecologic Cancer Detection

A new multi-omics assay distinguishes ovarian cancer from symptomatic non-cancer cases, aiding early-stage detection More...
12 Oct 2026
Image: Complement C7 was identified through multi-omics analysis, validated across MASLD cohorts, localized to hepatic stellate cell-rich fibrotic regions, and linked to extracellular matrix remodeling. (Image Credit: Dr. Takefumi Kimura from Shinshu University, Japan)

Multi-Omics Study Identifies Blood Marker for MASLD Progression

Researchers identify a blood-based marker that stratifies liver fibrosis and predicts future liver-related events in MASLD. More...
12 Oct 2026
Image: Laboratory specialists and clinicians from 48 countries participated in this survey. Countries are indicated in red. (Omosule, Catherine L., Lang, Tim, Geaghan, Sharon M., et al. Mapping pediatric cardiac troponin testing worldwide: results from the IFCC survey on emerging applications, standardization needs and access. Chemistry and Laboratory Medicine (CCLM), 2026. https://doi.org/10.1515/cclm-2026-0711)

Global Survey Finds Pediatric Troponin Testing Lacks Consistent Reference Intervals

New data reveal lack of pediatric troponin reference intervals, hindering interpretation and prompting development of standards. More...
12 Oct 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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