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Clinical Chemistry

Image: For decades, laboratories have adjusted total calcium for albumin, but growing evidence shows these corrections often perform poorly and may cause harm (image credit: iStock)

International Experts Recommend Ending Routine 'Corrected' Calcium Reporting

Guidelines recommend ending routine albumin-adjusted calcium reporting and prioritizing ionized calcium for key decisions. More...
20 May 2026
Image: An updated review finds that prostate cancer blood tests likely reduce the risk of death, revising earlier findings that evidence was insufficient (photo courtesy of iStock)

Long-Term Data Show PSA Screening Modestly Reduces Prostate Cancer Deaths

New data show PSA screening modestly cuts prostate cancer deaths but increases detection of earlier-stage disease. More...
20 May 2026
Image: Originally designed for lung cancer detection and resistance monitoring, the test also shows potential for identifying signals linked to pulmonary fibrosis (image credit: iStock)

Urine-Based Nanosensor Tracks Lung Cancer and Fibrosis Noninvasively

A new urine test tracks enzyme activity to support earlier, ongoing monitoring of lung cancer and pulmonary fibrosis. More...
15 May 2026
Image: Roche’s CE-Marked Elecsys pTau217 blood test is a single‑assay blood test measures phosphorylated tau 217, an indicator of amyloid pathology and a hallmark of Alzheimer’s disease (image credit: Shutterstock)

Blood-Based Alzheimer’s Test Gains CE Mark for Amyloid Pathology Detection

A new test measures pTau217 to rule in or rule out amyloid pathology, enabling earlier, less invasive Alzheimer’s assessment. More...
14 May 2026
Image: Processed on IDS’ random-access automation platforms, the comprehensive portfolio enables direct ChLIA measurement of total testosterone, SHBG, and free testosterone (photo courtesy of Revvity)

FDA-Cleared Assay Enables Comprehensive Automated Testosterone Testing

Revvity receives FDA clearance for total testosterone assay enabling comprehensive automated testing. More...
13 May 2026
Image: The addition of pTau 217 complements blood-based approaches for clinical decision-making in neurology workflows. The fully automated format supports scalability on the LUMIPULSE G platform (photo courtesty of Shutterstock)

CE-Marked Blood Biomarker Test Advances Automated Alzheimer’s Diagnostics

Fujirebio announced CE marking for the Lumipulse G pTau 217 Plasma assay, a fully automated test that quantitatively measures pTau 217 in human plasma. More...
13 May 2026
Image: The findings point to the feasibility of a quick, noninvasive urine-based approach to support earlier decision-making in multiple psychiatric conditions (photo credit: Shutterstock)

Noninvasive Urine Test May Support Earlier Diagnosis of Psychiatric Disorders

New data identify urinary metabolite signatures that may enable earlier, noninvasive identification of bipolar, ADHD and anorexia. More...
12 May 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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