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Clinical Chemistry

Image: The study analyzed saliva samples from people undergoing treatment for OCD (Image Credit: Adobe Stock)

Study Links Saliva-Based Epigenetic Signals to OCD Treatment Outcomes

New findings link DNA methylation markers to OCD psychotherapy response, supporting personalized treatment. More...
20 Oct 2026
Image: Cell culture of induced pluripotent stem cells (iPSCs). Neurons are shown in green and astrocytes in red. (Photo courtesy of Carlos Avilés Granados)

CSF Biomarker Meprin-Beta Increases in Alzheimer’s Disease

New findings show elevated active meprin-β in brain and CSF in Alzheimer’s disease, suggesting utility as a biomarker. More...
19 Oct 2026
Image: A new pilot rapid test for syphilis from a team led by Penn State researchers integrates two blood tests into one and detects bacteria at very low levels to detect the disease in its earliest stages. (Photo courtesy of Pan Research Lab / Penn State)

New One-Step Syphilis Test Could Enable Earlier Detection and Faster Treatment

A new rapid syphilis test combining treponemal and non-treponemal targets boosts low-titer detection, enabling earlier diagnosis. More...
19 Oct 2026
Image: Overview of available modalities in the MSK-IMPACT cohort (n = 52,236 patients), including longitudinal BMI trajectories, serologic laboratory tests, radiology-derived progression annotations and tumor genomic profiling. Human silhouette created in BioRender. (Castillon, V.J., Xie, A.X., Boscenco, S. et al. Nature Medicine (2026). https://doi.org/10.1038/s41591-026-04689-9)

Multimodal Clinical Data Models Predict Cachexia Risk Across Cancers

A new approach integrates routine labs, weight, imaging and genomics to map cachexia and predict patient risk. More...
16 Oct 2026
Image: The test identifies individuals more likely to have elevated brain amyloid, with PET used for confirmation (Image Credit: Adobe Stock)

Study Evaluates Alzheimer’s Blood Biomarker Across Racial and Ethnic Groups

New data show that a blood-based Alzheimer’s marker tracks brain amyloid across diverse groups. More...
15 Oct 2026
Image Credit: iStock

Blood Protein May Help Identify Treatment-Resistant Psychosis

New findings identify a potential blood biomarker for treatment-resistant psychosis that could help guide treatment decisions. More...
14 Oct 2026
Image: Schematic illustration of the operating principle of the enzyme-reaction-based highly sensitive biosensor (ESGNS) (Credit: Chihyun Kim, Wonjun Jo, Dayoung Chang, et al. Enzymatic sialylation–driven gold nanostructured platform for rapid and selective detection of sialic acid–deficient transferrin. Chemical Engineering Journal, 2026. https://doi.org/10.1016/j.cej.2026.182244)

Electrochemical Biosensor Rapidly Detects Cerebrospinal Fluid Leaks

A new electrochemical biosensor rapidly detects a cerebrospinal fluid marker to confirm leaks, supporting point-of-care testing More...
14 Oct 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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