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Clinical Chemistry

Image Credit: 123RF

NIH-Funded Study Targets Saliva-Based Long COVID Diagnosis

An AI approach analyzes salivary biomarkers to support long COVID diagnosis and predict risk of persistent symptoms. More...
01 Sep 2026
Image:  About 14.2 million Americans are eligible for annual lung cancer screening, but uptake remains low and LDCT false positives persist; CIZ1B may improve risk stratification and reduce uncertainty (Image Credit: Adobe Stock)

Validated Biomarker Blood Test Detects Early Lung Cancer and Supports Risk Assessment

Cizzle Bio’s CIZ1B ELISA biomarker test detects an early lung cancer-linked protein variant, complementing low-dose CT to clarify indeterminate findings. More...
01 Sep 2026
Image Credit: Adobe Stock

Machine Learning Model Uses Routine Lab Tests to Support Heart Failure Classification

An AI approach using 13 routine labs flags HFrEF to prioritize echocardiography and support rule-out triage. More...
01 Sep 2026
Image: Graphical Abstract (Daisuke Ito, Madoka Iida, Yohei Iguchi, et al. Fatty acid amide hydrolase inhibition for treatment of amyotrophic lateral sclerosis. JCI Insight. 2026;11(15):e198842. doi:10.1172/jci.insight.198842)

Blood Metabolite Signature Predicts ALS Progression and Points to Treatment Strategy

Researchers identify blood lipid markers of rapid ALS and show an enzyme-blocking treatment slows motor decline in models. More...
30 Aug 2026
Image: Study Design (Jerke, U., Kirchner, M., Bartolomaeus, T.U. et al. Nature Communcation (2026). https://doi.org/10.1038/s41467-026-75755-6)

Multiprotein Plasma Panel Identifies Remission in Vasculitis

An AI-guided proteomic panel of seven plasma proteins identifies vasculitis remission and distinguishes it from active disease. More...
27 Aug 2026
Image: The approach combines biomarker signals from donor kidney urine with the KDPI to estimate the likelihood of favorable long-term function (Image Credit: Shutterstock)

Rapid Urine Biomarker Panel Supports Better Kidney Transplant Decisions

A rapid three-biomarker urine test added to KDPI boosts prediction accuracy to 86% and may add more kidneys for transplant. More...
26 Aug 2026
Image: The method combines ultrasonic and fluorescence techniques to track amyloid aggregation in real time (Image Credit: Shutterstock)

Blood Test Measures Amyloid Seeding Activity to Detect Alzheimer’s Disease

A new blood test detects Alzheimer’s-related amyloid activity in plasma, identifying Alzheimer’s disease and MCI with over 90% accuracy in 24 hours. More...
25 Aug 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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