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Clinical Chemistry

Image: Graphical abstract (Pandya T, Zagorulya M, Leung MM, et al. Plasma signals of lung tumor promotion for molecular cancer prevention. Cell. 2026. doi:10.1016/j.cell.2026.05.005)

Plasma Protein Signature Predicts Lung Cancer Risk Up to Five Years Ahead

A 14-protein blood signature predicts lung cancer risk up to five years before diagnosis, beyond smoking status. More...
05 Jun 2026
Image: The monitoring system connects to drainage lines to detect infection biomarkers, including changes in glucose, lactate, pH, and flow rate, as brain fluid moves through them (Photo courtesy of the University of Waterloo)

Bedside CSF Monitor Detects Early Infection in Fluid Drains

A new bedside system continuously monitors CSF drain output to detect CSF infection and flow issues earlier in ICU care. More...
04 Jun 2026
Image: Graphical Abstract (Michael Scholz et al., Journal of Proteome Research (2026). DOI: 10.1021/acs.jproteome.5c01064)

Saliva-Based Test Detects Biochemical Signs of Sleep Loss

A new saliva test detects acute sleep deprivation with 94% accuracy, enabling rapid point-of-care screening. More...
04 Jun 2026
Image: Representational Models of Regional Aβ and Tau Deposition Across Plasma Stages (Salvadó G, Horie K, Barthélemy NR, et al. JAMA Neurology. May 26, 2026. doi:10.1001/jamaneurol.2026.1405)

Simple Dual-Tau Blood Test Detects and Stages Alzheimer’s Disease

A new two-tau blood test detects and stages Alzheimer's with PET-like accuracy, enabling less invasive routine assessment. More...
03 Jun 2026
Image: The study addressed whether circulating markers of hallmark Alzheimer’s pathology align with subtle cognitive differences before clinical diagnosis (image credit: Adobe Stock)

Alzheimer’s Blood Biomarkers Linked to Early Cognitive Differences Before Dementia

For the first time, researchers found Alzheimer’s blood biomarkers linked to minor cognitive differences in midlife adults without dementia. More...
03 Jun 2026
Image: New urine test provides a simple way to screen for autism in children (Photo courtesy of Andy DeLisle/ASU Knowledge Enterprise)

Urine-Based Test Shows Promise for Autism Screening in Children

A new urine test measuring 17 gut microbe-derived metabolites distinguished children with autism with high accuracy. More...
28 May 2026
Image: Characterization of EV separated by distinct methods (Photo courtesy of Yuanyuan Liu, Yanbin Guo et al. Engineering, doi.org/10.1016/j.eng.2025.12.009)

Liquid Biopsy Biomarkers May Improve Childhood Epilepsy Diagnosis

New findings show biomarkers in extracellular vesicles can help diagnose childhood epilepsy. More...
27 May 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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