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Clinical Chemistry

Image: Overview of available modalities in the MSK-IMPACT cohort (n = 52,236 patients), including longitudinal BMI trajectories, serologic laboratory tests, radiology-derived progression annotations and tumor genomic profiling. Human silhouette created in BioRender. (Castillon, V.J., Xie, A.X., Boscenco, S. et al. Nature Medicine (2026). https://doi.org/10.1038/s41591-026-04689-9)

Multimodal Clinical Data Models Predict Cachexia Risk Across Cancers

A new approach integrates routine labs, weight, imaging and genomics to map cachexia and predict patient risk. More...
16 Oct 2026
Image: The test identifies individuals more likely to have elevated brain amyloid, with PET used for confirmation (Image Credit: Adobe Stock)

Study Evaluates Alzheimer’s Blood Biomarker Across Racial and Ethnic Groups

New data show that a blood-based Alzheimer’s marker tracks brain amyloid across diverse groups. More...
15 Oct 2026
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Blood Protein May Help Identify Treatment-Resistant Psychosis

New findings identify a potential blood biomarker for treatment-resistant psychosis that could help guide treatment decisions. More...
14 Oct 2026
Image: Schematic illustration of the operating principle of the enzyme-reaction-based highly sensitive biosensor (ESGNS) (Credit: Chihyun Kim, Wonjun Jo, Dayoung Chang, et al. Enzymatic sialylation–driven gold nanostructured platform for rapid and selective detection of sialic acid–deficient transferrin. Chemical Engineering Journal, 2026. https://doi.org/10.1016/j.cej.2026.182244)

Electrochemical Biosensor Rapidly Detects Cerebrospinal Fluid Leaks

A new electrochemical biosensor rapidly detects a cerebrospinal fluid marker to confirm leaks, supporting point-of-care testing More...
14 Oct 2026
Image Credit: iStock

Blood Protein Panel Supports Monitoring of Treated Celiac Disease

Targeted serum proteomics identifies protein patterns tracking celiac activity and intestinal damage on a gluten-free diet. More...
13 Oct 2026
Image Credit: Adobe Stock

Hemoglobin Levels May Help Signal Long-Term Dementia Risk

Researchers identify abnormal hemoglobin as a marker for increased long-term dementia risk from routine blood tests. More...
12 Oct 2026
Image: The test is designed to detect ovarian cancer early in symptomatic women, addressing a critical diagnostic gap in a cancer associated with high mortality. (Image Credit: iStock)

Liquid Biopsy Platform Shows Promise for Early Gynecologic Cancer Detection

A new multi-omics assay distinguishes ovarian cancer from symptomatic non-cancer cases, aiding early-stage detection More...
12 Oct 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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