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Clinical Chemistry

Image: Researchers use a novel immobilized liposome-bound gel beads method to measure CEC levels and their association with cardiovascular risks (Photo courtesy of Institute of Science Tokyo)

Simple Blood-Based Cholesterol Efflux Assay Identifies High-Risk Coronary Plaque Features

A new blood test measuring cholesterol efflux capacity flags vulnerable coronary plaque features, improving risk stratification. More...
12 Jun 2026
Image: Three gray matter (GM) structural networks related to default mode network (DMN). Three GM structural networks related to DMN that were identified are shown. (A) anterior DMN; (B) posterior DMN-I, including the posterior cingulate cortex (PCC) and precuneus; and (C) posterior DMN-II, including the PCC, precuneus, inferior parietal cortex, and lateral temporal cortices. (Photo courtesy of Nagaya et al., 2026, PLOS One, CC-BY 4.0)

Plasma Vitamin C Levels Associated with Brain Structure and Connectivity in Aging

New data link plasma vitamin C to greater gray matter volume and stronger default mode network connectivity in older adults. More...
11 Jun 2026
Image: General workflow for liquid chromatography/mass spectrometry-based metabolomics (Rowles, J.L., Patti, G.J. Nature Reviews Cancer (2026). doi.org/10.1038/s41568-026-00908-0)

Mass Spectrometry Detects Tumor Metabolites for Cancer Monitoring

A mass spectrometry-based metabolomics and isotope tracer approach maps in vivo tumor fuel use to improve patient monitoring More...
11 Jun 2026
Image: DNlite measures urinary post-translationally modified Fetuin-A (uPTM-FetA), a biomarker linked to kidney stress, inflammation, metabolic dysfunction, and progressive renal injury (Photo courtesy of Bio Preventive Medicine Corp)

Urinary Biomarker Assay Predicts Kidney Disease Progression Beyond Standard Measures

A new urinary biomarker assay may enable earlier and more precise risk stratification beyond albuminuria and eGFR. More...
10 Jun 2026
Image: Graphical abstract (Pandya T, Zagorulya M, Leung MM, et al. Plasma signals of lung tumor promotion for molecular cancer prevention. Cell. 2026. doi:10.1016/j.cell.2026.05.005)

Plasma Protein Signature Predicts Lung Cancer Risk Up to Five Years Ahead

A 14-protein blood signature predicts lung cancer risk up to five years before diagnosis, beyond smoking status. More...
05 Jun 2026
Image: The monitoring system connects to drainage lines to detect infection biomarkers, including changes in glucose, lactate, pH, and flow rate, as brain fluid moves through them (Photo courtesy of the University of Waterloo)

Bedside CSF Monitor Detects Early Infection in Fluid Drains

A new bedside system continuously monitors CSF drain output to detect CSF infection and flow issues earlier in ICU care. More...
04 Jun 2026
Image: Graphical Abstract (Michael Scholz et al., Journal of Proteome Research (2026). DOI: 10.1021/acs.jproteome.5c01064)

Saliva-Based Test Detects Biochemical Signs of Sleep Loss

A new saliva test detects acute sleep deprivation with 94% accuracy, enabling rapid point-of-care screening. More...
04 Jun 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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