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全胆固醇测试可为代谢异常提供线索

By LabMedica International staff writers
Posted on 22 Nov 2010
一种详细的血脂图谱可帮助医生诊断多囊卵巢综合征(PCOS),该症是导致女性不孕的头号原因。

被称为Vertical Auto Profile (VAP)的全胆固醇试剂盒能分别测定血液中胆固醇的15种成份,而且它能鉴定的血脂异常种类比标准的低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、总胆固醇和甘油三酯多得多。

该VAP测试是鉴定糖尿病的一种先兆——代谢综合征的唯一一种胆固醇测试。VAP扩展型血脂测试由Atherotech Diagnostics公司(Birmingham, AL, USA; www.atherotech.com)研发,可报告22种血液"胆固醇”成份,包括对非空腹直接LDL及脂蛋白所有子类的准确测量。

PCOS会增大心脏病、胰岛素耐受、糖尿病和某些癌症的风险。这也是育龄妇女最常见的代谢异常,美国全国范围内有500万到1000万妇女受此困扰。虽然没有单独的测试去诊断该疾病,但详细的血脂图谱却是有用的。PCOS的四种主要症状是月经不调、体重增加、睾丸激素水平高和代谢紊乱,包括胆固醇水平异常。结果显示,PCOS患者总胆固醇和甘油三酯的水平较高,而高密度脂蛋白2的水平较低——它是一种具有高度保护性的HDL亚型。

专攻PCOS的医师Steven Foley大夫说:"对于我来说,这是评估女患者的高胆固醇以及多囊卵巢综合症的最准确、最简单的方法。这对于女性治疗计划的制定特别有价值,也有助于监测治疗效果。”

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