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Pathology

Image: 3D reconstruction of an ATTR-F64S amyloid fibril extracted from skin tissue of a living patient (Photo courtesy of UNIGE)

Skin Biopsy Offers New Diagnostic Method for Neurodegenerative Diseases

Minimally invasive skin biopsy could enable early diagnosis of neurodegenerative diseases. More...
29 Jan 2026
Image: Fluorescently labeled cell showing the cell body in green, the cytoskeleton in blue, the cell nucleus in yellow (Photo courtesy of Chalom Zemmour/Center for Nanoscience and Nanotechnology)

Fast Label-Free Method Identifies Aggressive Cancer Cells

A new “mechanical sensor” surface identifies aggressive cancer cells without the use of labels. More...
29 Jan 2026
Image: Cancer-specific small RNAs released into blood act as molecular barcodes that reveal tumor identity (Photo courtesy of Arc Institute)

Blood Test Could Detect Molecular Barcodes Capable of Distinguishing Cancer Types

Hidden cancer RNAs have emerged as powerful blood-based signals for detection. More...
28 Jan 2026
Image: Cell nuclei are highlighted in purple, while the remaining tissue is shown in pink – valuable information for diagnostics (Photo courtesy of Hereon/Dominik John)

New X-Ray Method Promises Advances in Histology

An X-ray histology technique visualizes stained tissue structures in full 3D without physical sectioning. More...
28 Jan 2026
Image: Single-cell sequencing reveals how early cancer-driving mutations alter gene activity in individual cells within human tissue (Photo courtesy of Shutterstock)

Single-Cell Profiling Technique Could Guide Early Cancer Detection

Single-cell sequencing maps pre-cancerous mutations inside human tissues for the first time. More...
23 Jan 2026
Image: Comparative analysis of SRUV PA virtual histology images of human kidney tissues (Byullee Park et al., Science Advances, 2025; DOI:10.1126/sciadv.adz1820)

Intraoperative Tumor Histology to Improve Cancer Surgeries

An AI-powered imaging technique enables real-time cancer margin detection during surgery. More...
20 Jan 2026
Image: Microscopy images of colon tissue samples from IBD patients under remission (left) and with active disease (right) (Photo courtesy of Emily Thompson)

Rapid Stool Test Could Help Pinpoint IBD Diagnosis

A luminescent stool test targets gut-specific inflammation to improve IBD diagnosis. More...
19 Jan 2026
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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