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Microbiology

Image: Graph of mass-spectrometry-based mapping of tissue-specific protein in blood plasma, from the study of sepsis using quantitative targeted proteomics (Photo courtesy of Malmström laboratory, Lund University).

Protein Patterning: Novel Tool for Studying Sepsis

In a new approach using quantitative targeted proteomics, researchers have for the first time developed a way to use mass-spectrometry to measure hundreds of organ proteins in a single blood sample. The resulting protein patterns can help determine sepsis severity, which organs have been damaged, and may lead to faster diagnostics.  More...
18 Jan 2016
Image: Histopathology of chronic viral hepatitis C, necrosis and inflammation are prominent (Photo courtesy of University of Utah).

Hepatitis C Positive Antibody Test Leads to Molecular Assay

Conventional laboratory and medical practice for Hepatitis C virus infection involves referring a patient for a second office visit and blood draw if the initial antibody screening test produces a positive result.  More...
18 Jan 2016
Image: Novel Immunoassay for Dengue virus (Photo courtesy of Fraunhofer IZI).

Novel Immunoassay Developed to Diagnose Dengue

Until now, it has been difficult to diagnose whether someone is suffering from dengue fever or whether they have contracted another flavivirus, such as yellow fever, West Nile virus, or Tick-borne encephalitis virus.   More...
17 Jan 2016
Image: The female Aedes aegypti mosquito that transmits the Zika virus (Photo courtesy of James Gathany/CDC).

Zika Virus Tied to Potential Brain Damage in Newborns

The Brazilian authorities are investigating thousands of suspected cases of microcephaly in babies born to mothers infected with the mosquito-borne Zika virus, while they were pregnant.  More...
11 Jan 2016
Image: Photomicrograph of a peripheral blood smear showing schizonts and trophozoite stages of Plasmodium falciparum (Photo courtesy of Chiang Mai University).

Ultrasensitive Assay Detects Asymptomatic Low-Density Malaria

Highly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions and while traditional microscopy and rapid diagnostic tests are suitable for the diagnosis of symptomatic malaria infection, more sensitive tests are needed to screen for low-density, asymptomatic infections.  More...
06 Jan 2016
Image: Light micrograph of Bacillus cereus in a small colony variant (SCV) (Photo courtesy of Markus Kranzler/Vetmeduni Vienna).

A Bacterial Lifestyle Switch Provides Antibiotic Resistance

Researchers have reported for the first time that following contact with certain antibiotics the pathogenic Bacillus cereus can switch into a special slowed-down mode and form small colony variants that are difficult to diagnose and almost impossible to treat with certain antibiotics.  More...
06 Jan 2016
Image: Colored Transmission electron micrograph of Clostridium difficile forming an endospore (red) (Photo courtesy of Dr. J. Thomas Lamont).

New Infectious Disease Test Promises Quick Diagnosis

Early detection of specific pathogens has long been recognized as a vital strategy in the control of infectious diseases because it can lead to timely care of patients and prevent potential outbreaks.   More...
05 Jan 2016
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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