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Immunology

Image: The CrAg lateral flow assay to detect cryptococcal antigens (Photo courtesy of Immuno-Mycologics).

Lateral Flow Immunoassay Validated for Detection of Cryptococcal Antigen

Cryptococcosis is an important and potentially lethal opportunistic infection in immunocompromised patients, especially in human immunodeficiency virus infected and organ transplant patients.   More...
23 Feb 2015
Image: The BOND-MAX fully automatic immunochemistry stainer (Photo courtesy of Leica).

Minimally Invasive Test Identifies Patients with Reflux Symptoms

A new, minimally invasive cell sampling device coupled with assessment of trefoil factor 3 expression can be used to identify patients with reflux symptoms who warrant endoscopy to diagnose Barrett's esophagus.  More...
16 Feb 2015
Image: Newly developed diagnostic smartphone accessory device successfully performed point-of-care HIV and syphilis tests in Rwanda from finger-prick whole blood in 15 minutes, operated by healthcare workers easily trained via a software app (Photo courtesy of Samiksha Nayak for Columbia Engineering).

A First – Smartphone Diagnostic Device Replicates Quality of Lab Blood Test

Researchers have developed a hand-held smartphone accessory that can perform a low-cost, point-of-care, lab-quality test that simultaneously detects 3 infectious disease markers from a single finger-prick blood sample in only 15 minutes. The device can also be further developed to test for additional biomarkers.  More...
09 Feb 2015
Image: The Histamine ELISA kit (Photo courtesy of Enzo Life Science).

New ELISA Kit Measures Histamine in Diverse Biological Specimens

A newly released ELISA kit measures histamine or N-methyl histamine in a wide variety of biological specimens.  More...
05 Feb 2015
Image: A psoriatic plaque, showing a silvery center surrounded by a reddened border (Photo courtesy of Dr. James Heilman).

Proteins Likely to Trigger Psoriasis Identified

Psoriasis is an autoimmune skin disease characterized by well-demarcated areas of red, raised and scaly skin next to areas of normal-appearing skin and is an autoimmune disease where the body launches an abnormal immune response against its own tissues.   More...
03 Feb 2015
Image: Glass microbubbles labeled with phycoerythrin-conjugated biotin (A). Schematic of buoyancy activated cell sorting (BACS). Surface-functionalized glass microbubbles bind to target cells after a brief rotary mixing (1-3). Cells attached by glass microbubbles float and are separated spontaneously by buoyancy (4) (B) (Photo courtesy of Technology).

Glass Microbubbles Separate CD4+ T Cells by Buoyancy

For human immunodeficiency virus infected patients the number of CD4+ T lymphocytes in peripheral blood is an important marker for monitoring disease progression of acquired immune deficiency syndrome and treatment efficacy.   More...
01 Feb 2015
Image: Photomicrograph of the filarial nematode Wuchereria bancrofti in a blood film (Photo courtesy of Dr. Mae Melvin).

Common Human Protein Linked to Adverse Parasitic Worm Infections

Parasitic helminths, which infect an estimated two billion people worldwide, represent a significant global public health problem and infection is associated with life-long morbidity including growth retardation and organ failure.  More...
21 Jan 2015
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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