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Molecular Diagnostics

Image: A novel computational tool can accurately identify RFC1 genetic changes linked to certain forms of peripheral neuropathy (photo courtesy of Adobe Stock)

New Computational Tool Reveals Genetic Driver of Idiopathic Neuropathy

An AI approach to genome analysis identifies hard-to-detect genetic expansions, improving diagnosis of unexplained neuropathy. More...
20 May 2026
Image: Researchers identified eight new DNA pattern signatures that could help refine diagnostics and guide targeted therapy in breast cancer (image credit: 123RF)

Breast Cancer-Specific Signatures Link Genome Instability to Outcomes

Researchers identify eight breast cancer copy-number signatures to improve detection and guide terapy selection. More...
19 May 2026
Image: TrueMRD uses a whole-genome, tumor-informed approach that analyzes patient-specific tumor variants across the entire genome in every sample tested (photo courtesy of Veracyte)

Whole-Genome MRD Test Detects Early Recurrence in Muscle-Invasive Bladder Cancer

A new whole-genome MRD test gains Medicare coverage to detect post-treatment MIBC recurrence months earlier than imaging. More...
19 May 2026
Image: Researchers found that tumor DNA fragments in blood can reveal ongoing prostate cancer growth even when current tests show little change (image credit: Adobe Stock)

Blood Test Detects Early Nonresponse in Metastatic Prostate Cancer

A new ctDNA blood test identifies high-risk nonresponse in metastatic prostate cancer at 6–12 weeks, guiding earlier therapy. More...
19 May 2026
Image: CellDx-Tissue is a qualitative IVD test that uses targeted NGS of DNA and RNA isolated from FFPE solid tumor tissue to analyze 517 cancer-associated genes (image credit: Adobe Stock)

FDA-Cleared Genomic Profiling Assay Guides Treatment Selection in Solid Tumors

A new dual-analyte NGS assay enables tumor profiling across 517 genes with RNA-verified fusions for therapy selection. More...
19 May 2026
Image: Findings show that ctDNA testing may help identify candidates for radiotherapy and refine management by signaling when a cancer has changed or developed resistance (image credit: 123RF)

ctDNA Blood Test Could Help Guide Radiotherapy in Patients with Limited Metastases

A circulating tumor DNA (ctDNA) blood test could help select and monitor oligometastatic patients for radiotherapy. More...
18 May 2026
Image: Signatera CDx uses ctDNA analysis to identify residual tumor-derived genetic material after definitive treatment (image credit: Adobe Stock)

FDA-Approved MRD Blood Test Guides Adjuvant Bladder Cancer Therapy

Natera’s Signatera CDx has been approved by the U.S. FDA as a companion diagnostic for use with adjuvant atezolizumab in MIBC. More...
18 May 2026
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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