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Image: The acquisition of Proscia advances Agilent’s efforts to expand its pathology portfolio and strengthens its competitive position in a rapidly growing market.

Agilent Acquisition of Proscia to Advance AI-Enabled Digital Pathology Workflows

Agilent Technologies has entered into a definitive agreement to acquire Proscia, a provider of digital pathology software for clinical and life-sciences customers.  Read more
14 Oct 2026 | Industry
Image: Diazyme Laboratories has acquired Alfa Wassermann Diagnostic Technologies (AWDT), an FDA-registered manufacturer of chemistry systems and reagents, from CARR Biosystems

Diazyme Expands Chemistry Testing Portfolio With Alfa Wassermann Acquisition

Diazyme Laboratories, Inc. has acquired the business of Alfa Wassermann Diagnostic Technologies LLC  from CARR Biosystems. Read more
14 Oct 2026 | Industry
Image: AISight Dx is a cloud-native digital pathology platform that streamlines case management, slide review, and collaboration to improve anatomic pathology workflows (Photo courtesy of PathAI)

Digital Pathology Collaboration Expands Laboratory Access to AI-Driven Diagnostics

An AI platform integration embeds digital pathology models into case workflows, expanding access to diagnostic decision support. Read more
14 Oct 2026 | Industry
Image: GenomeNext uses a pangenome reference to better represent human genetic diversity and improve variant detection, while GenomeReveal integrates RNA analysis to help interpret certain DNA findings (Photo courtesy of Ambry Genetics)

Whole Genome Sequencing Solution Targets Unsolved Rare Disease Cases

A new WGS system with pangenome reference, RNA analysis, and reanalysis improves rare disease diagnostic yield across populations. Read more
14 Oct 2026 | Molecular Diagnostics
Image Credit: iStock

Blood Protein Panel Supports Monitoring of Treated Celiac Disease

Targeted serum proteomics identifies protein patterns tracking celiac activity and intestinal damage on a gluten-free diet. Read more
13 Oct 2026 | Clinical Chem.
Image Credit: 123RF

Oral and Lung Microbiome Changes Linked to Severe Long Covid Symptoms

New findings link oral and lung microbiome changes to severe long COVID, reduced lung function, and neurological and digestive symptoms. Read more
13 Oct 2026 | Microbiology
Image: A health worker from the Mfou District Hospital collects a blood sample for the study (Photo courtesy of Sandrine Nsango, PhD)

Study Finds Distinct Malaria Parasites Linked to Sickle Cell Trait Protection

New findings link sickle cell trait to distinct malaria parasite genotypes, with similar infection rates but lower disease risk. Read more
13 Oct 2026 | Microbiology
Image: Image: Graphical Abstract (Nagy, G.R., Munkácsy, G., Murmu, A. et al. Beyond the linear genome: how reference bias threatens preventive medicine and geroscience. GeroScience, 2026. https://doi.org/10.1007/s11357-026-02436-z)

Study Shows How Genome Reference Bias Can Mislead Preventive Testing

New findings show broader genome references may reduce false positives in whole-genome sequencing. Read more
13 Oct 2026 | Molecular Diagnostics
Image Credit: Adobe Stock

Hemoglobin Levels May Help Signal Long-Term Dementia Risk

Researchers identify abnormal hemoglobin as a marker for increased long-term dementia risk from routine blood tests. Read more
12 Oct 2026 | Clinical Chem.
Image: The test is designed to detect ovarian cancer early in symptomatic women, addressing a critical diagnostic gap in a cancer associated with high mortality. (Image Credit: iStock)

Liquid Biopsy Platform Shows Promise for Early Gynecologic Cancer Detection

A new multi-omics assay distinguishes ovarian cancer from symptomatic non-cancer cases, aiding early-stage detection Read more
12 Oct 2026 | Clinical Chem.
Image: Complement C7 was identified through multi-omics analysis, validated across MASLD cohorts, localized to hepatic stellate cell-rich fibrotic regions, and linked to extracellular matrix remodeling. (Image Credit: Dr. Takefumi Kimura from Shinshu University, Japan)

Multi-Omics Study Identifies Blood Marker for MASLD Progression

Researchers identify a blood-based marker that stratifies liver fibrosis and predicts future liver-related events in MASLD. Read more
12 Oct 2026 | Clinical Chem.
Image: WashU Medicine researchers have found that a ratio between two immune cell types can reveal whether someone stays healthy or may face a higher risk of future disease. They found that having more granzyme K-producing white blood cells tipped the scale toward healthy aging, while having more granzyme B-producing cells was associated with chronic disease and even death. (Photo courtesy of Sara Moser/WashU Medicine)

Blood-Based Immune Aging Map Could Help Spot Disease Risk Earlier

Researchers identify an immune cell marker that gauges immune aging and predicts 10-year mortality and disease risk. Read more
12 Oct 2026 | Immunology
Image: Laboratory specialists and clinicians from 48 countries participated in this survey. Countries are indicated in red. (Omosule, Catherine L., Lang, Tim, Geaghan, Sharon M., et al. Mapping pediatric cardiac troponin testing worldwide: results from the IFCC survey on emerging applications, standardization needs and access. Chemistry and Laboratory Medicine (CCLM), 2026. https://doi.org/10.1515/cclm-2026-0711)

Global Survey Finds Pediatric Troponin Testing Lacks Consistent Reference Intervals

New data reveal lack of pediatric troponin reference intervals, hindering interpretation and prompting development of standards. Read more
12 Oct 2026 | Clinical Chem.

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Clinical Chemistry

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Study Questions Broad Fasting Requirements Before Routine Blood Tests
Elevated Lipoprotein(a) Linked to Long-Term Progression of Carotid Atheroscleros...
Lollipop-Inspired Device Measures Acetaminophen Levels in Saliva
Image: Dr. Olivia Belbin, head of the Molecular Neurodegeneration Group at IR Sant Pau and study corresponding author, with Alba Cervantes (right), first author and IR Sant Pau researcher (Photo courtesy of IR Sant Pau)

Blood Biomarker Detects Alzheimer’s Changes Decades Before Symptoms in Down Syndrome

Alzheimer’s disease can begin altering the brain long before clinical symptoms appear, creating a challenge for early-stage detection and research. People with Down syndrome face a particularly high age-related... Read more

Molecular Diagnostics

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Genomic Screening Expands Detection of Treatable Conditions in Newborns
Age-Based Genetic Testing May Miss Most Inherited Cancer Risk Variants
New NGS Suite Expands Clonality and MRD Research in Lymphoid Malignancies
Image: The AidaBREAST assay integrates multimodal data to provide patient-specific 10-year recurrence risk and individualized predictions of radiation therapy benefit (photo courtesy of PreludeDx)

Validated Test Predicts Recurrence Risk and Radiation Benefit in Early-Stage Breast Cancer

For women with early-stage invasive breast cancer who undergo breast-conserving surgery, clinicians must assess both the risk of locoregional recurrence and the potential benefit of adjuvant radiation therapy.... Read more

Hematology

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Updated Ferritin Thresholds Improve Detection of Iron Deficiency
New Automated Hemostasis Systems Become Available Across US Laboratories
Variation in AML Residual Disease Testing Prompts Push for Standardization
Image Credit: Adobe Stock

New Donor Genetic Marker May Help Predict Stem Cell Transplant Success

Donor selection for hematopoietic stem cell transplantation plays a major role in relapse risk and survival for patients with blood cancers and other blood disorders. Despite advances in genotyping, uncertainty... Read more

Immunology

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Prototype Point-of-Care Test Aims to Improve Neonatal Sepsis Diagnosis
Single-Tier Lyme Disease Test Shows High Sensitivity in Early Infection
New Web-Based Platform Helps Autoimmune Laboratories Manage Testing Complexity
Image Credit: Adobe Stock

Blood-Based Immune Signal Could Reveal Lung Cancer Risk Before Tumors Develop

Lung cancer remains difficult to detect before symptoms appear, when advanced disease is harder to treat. In the U.K., about 32,800 people die from lung cancer each year, and only 11.1% of those diagnosed... Read more

Microbiology

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Nanodroplet CRISPR Technology Supports Rapid, Multiplexed Mycobacterial Identifi...
Genomic Workflow Identifies Fungal Pathogens Before Blood Cultures Turn Positive
FDA-Cleared Multiplex PCR Test Detects 13 Respiratory Pathogens in a Single Samp...
Image: Invasive aspergillosis (IA) is a potentially life-threatening infection caused by Aspergillus mold that primarily affects people with severely weakened immune systems. (Image Credit: Adobe Stock)

Rapid Urine Test Aids Diagnosis of Invasive Aspergillosis

Invasive aspergillosis is an uncommon mold infection in the general population but can pose serious risks for people with weakened immune defenses. Diagnosis can be difficult because existing approaches... Read more

Pathology

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Rapid Mass Spectrometry Test May Aid Glioma Margin Decisions
Genomic Classifier Predicts Benefit From Adding Hormone Therapy to Salvage Prostate...
New AI Model Maps Where Glioblastoma Could Return After Surgery
Image: Overview of the multiple-instance learning (MIL) workflow, in which each TMA core image is represented as a bag of patches that are encoded and aggregated to generate a slide-level prediction. (Giner F, Pastor-Naranjo Á, Meseguer P, et al. International Journal of Molecular Sciences, 2026. DOI: 10.3390/ijms27156864)

AI Histopathology Tool Distinguishes Ewing Sarcoma for Diagnosis

Ewing sarcoma is a rare malignant tumor that mainly affects children, adolescents, and young adults. It usually arises in bone but can also develop in soft tissue, where its microscopic appearance may... Read more

Technology

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Laser-Enhanced Assay Boosts Sensitivity for Colorectal Cancer Biomarker Detectio...
New Automation Workflow Streamlines NGS Library Preparation for High-Volume Labs
ADLM Calls for CLIA Updates to Support Safe AI Use in Laboratory Medicine
Image: The laser-based photoacoustic spectroscopy setup consists of a Mid-IR laser equipped with three QCL modules covering wavelengths from 5.6 μm to 12.9 μm, two silver coated mirrors (SCM), a dichroic mirror (DM) with a transmittance of 90%, a thermal power sensor head (PM) to monitor the output laser power, a mechanical chopper (MC) for frequency modulation and a CEPAS-detector with a self-designed swab holder (SH). (Credit: Graunke, T., Scholz, T., Pieniak, M. et al. Scientific Reports (2026). https://doi.org/10.1038/s41598-026-68298-9)

Laser-Based Swab Analysis Shows Promise for Detecting Disease-Linked Odor Patterns

Disease-related changes in volatile organic compounds can alter body odor, producing measurable patterns in exhaled breath and bodily fluids. Current analytical methods can be complex, time-consuming,... Read more

Industry

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European Approval Expands Liquid Biopsy Use in Advanced Breast Cancer Testing
Regulatory Milestone Expands Access to Blood-Based Neurology Biomarker Testing in...
Collaboration Advances Automated Benchtop Platform for Routine Blood Testing
Image: Natera\'s MCED assay analyzes cell-free DNA in blood to screen for multiple cancers (Image Credit: Adobe Stock)

Multi-Cancer Screening Blood Test Gains FDA Breakthrough Designation

Natera Inc.’s (Austin, TX, USA) multi-cancer early detection (MCED) assay has received Breakthrough Device designation (BDD) from the U.S. Food and Drug Administration (FDA). The assay analyzes cell-free... Read more

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