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In Other News

Image: The blood test offers a faster and less invasive tool for Alzheimer’s diagnosis (Photo courtesy of Shutterstock)

Blood Test Accurately Detects Brain Amyloid Pathology in Symptomatic Patients

New research has reinforced the use of a novel blood test as a highly accurate tool for detecting brain amyloid pathology in symptomatic patients, helping healthcare professionals in diagnosing Alzheimer’s disease. Read more
01 Dec 2025 | Molecular Diagnostics
Image: The AI model uses routine pathology slides to predict rectal cancer treatment response (Photo courtesy of UCL)

AI Tool Predicts Treatment Success in Rectal Cancer Patients

Artificial intelligence (AI) may soon help clinicians identify which rectal cancer patients are likely to respond well to treatment, using only the routine biopsy slides already obtained at diagnosis. Read more
01 Dec 2025 | Pathology
Image: The test detects Lyme-causing bacteria with far greater sensitivity than standard tests (Photo courtesy of Shutterstock)

New Molecular Test Improves Diagnostic Accuracy of Lyme Disease

Diagnosing Lyme disease early remains one of the biggest challenges in infectious disease care. The condition is increasing across the United States, especially in the Northeast, although many patients never develop the classic bull’s-eye rash, and early antibody tests frequently return false negatives. Read more
01 Dec 2025 | Molecular Diagnostics
Image: The SMART-ID Assay delivers broad pathogen detection without the need for culture (Photo courtesy of Scanogen)

Rapid Assay Identifies Bloodstream Infection Pathogens Directly from Patient Samples

Bloodstream infections in sepsis progress quickly and demand rapid, precise diagnosis. Current blood-culture methods often take one to five days to identify the pathogen, leaving clinicians to treat blindly with broad-spectrum antibiotics. Read more
28 Nov 2025 | Microbiology
Image: Radboudumc is the first hospital in the world to use a new genetic test on a large scale in clinical practice (Photo courtesy of Radboudumc)

New Genetic Test Enables Faster Diagnosis of Rare Diseases

Rare disease diagnosis often involves a long and uncertain search for the underlying genetic cause. Traditional testing requires multiple separate analyses, although many patients remain without answers. Read more
28 Nov 2025 | Molecular Diagnostics
Image: New insights from a study link blood markers and airway bacteria to COPD exacerbation risk (Photo courtesy of Shutterstock)

Blood Test and Sputum Analysis Predict Acute COPD Exacerbation

Chronic obstructive pulmonary disease (COPD) remains a major contributor to global illness, largely driven by cigarette smoking and marked by irreversible lung damage. Read more
27 Nov 2025 | Pathology
Image: The new low-cost urine test detects SORD neuropathy earlier and more reliably than genetic panels (Photo courtesy of 123RF)

Urine Test Detects Inherited Neuropathy Missed by Genetic Screening

Sorbitol dehydrogenase (SORD)-related neuropathy is one of the most common inherited nerve disorders, yet diagnosis often lags because current genetic screens frequently miss the causal gene. Read more
27 Nov 2025 | Molecular Diagnostics
Image: The genomic test also predicts which SCC patients are most likely to benefit from adjuvant radiation therapy (Photo courtesy of Castle Biosciences)

Genomic Test Predicts Risk of SCC Metastasis

Managing squamous cell carcinoma (SCC) of the skin in patients with one or more risk factors is a significant clinical challenge, especially as SCC-related deaths are now estimated to exceed those from melanoma. Read more
27 Nov 2025 | Molecular Diagnostics
Image: The small chip device separates cancer cells from the bloodstream for treating pancreatic cancer (Photo courtesy of Sana Sheybanikashani/UIC)

Microfluidic Device Predicts Pancreatic Cancer Recurrence After Surgery

Pancreatic ductal adenocarcinoma is one of the deadliest cancers, difficult to detect early, and prone to recurring in nearly 70% of patients after treatment. Read more
26 Nov 2025 | Molecular Diagnostics
Image: The AI tool combines patient data and images to detect melanoma (Photo courtesy of Professor Gwangill Jeon/Incheon National University)

AI Tool to Transform Skin Cancer Detection with Near-Perfect Accuracy

Melanoma continues to be one of the most difficult skin cancers to diagnose because it often resembles harmless moles or benign lesions. Read more
26 Nov 2025 | Pathology
Image: The multiplex molecular assay rapidly identifies three major fungal pathogens causing serious respiratory disease (Photo courtesy of Adobe Stock)

New Molecular Test Simultaneously Detects Three Major Fungal Infections

Serious fungal infections associated with soil exposure remain difficult to diagnose promptly, especially in regions where Histoplasma, Blastomyces, and Coccidioides are endemic. Read more
26 Nov 2025 | Molecular Diagnostics
Image: RMIT’s Distinguished Professor Magdalena Plebanski and WEHI’s Professor Clare Scott AM in the lab (Photo courtesy of WEHI)

Blood Test Guides More Effective Ovarian Cancer Treatment

Ovarian cancer affects hundreds of thousands of women worldwide each year, yet only some respond to PARP inhibitor therapy, which targets tumors with defective DNA repair. Read more
25 Nov 2025 | Molecular Diagnostics
Image: High-resolution immune profiling can reveal how MOGAD differs from MS at the cellular level (Photo courtesy of Shutterstock)

Unique Immune Signatures Distinguish Rare Autoimmune Condition from Multiple Sclerosis

Myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is a rare autoimmune disorder in which the immune system attacks the myelin sheath in the central nervous system. Read more
25 Nov 2025 | Pathology
Image: The ARi-FL fluorescent probe offers a clearer view of tumor behavior and treatment resistance (J. Med. Chem. 2025, 68, 15, 15812-15827)

Chemical Imaging Probe Could Track and Treat Prostate Cancer

Prostate cancer remains a leading cause of illness and death among men, with many patients eventually developing resistance to standard hormone-blocking therapies. Read more
25 Nov 2025 | Clinical Chem.

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Clinical Chemistry

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VOCs Show Promise for Early Multi-Cancer Detection
Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC...
Gold Nanoparticles to Improve Accuracy of Ovarian Cancer Diagnosis
Image: A discrepancy between creatinine- and cystatin C-based kidney function readings may reveal higher health risks (Photo courtesy of 123RF)

Mismatch Between Two Common Kidney Function Tests Indicates Serious Health Problems

Creatinine has long been the standard for measuring kidney filtration, while cystatin C — a protein produced by all human cells — has been recommended as a complementary marker because it is influenced... Read more

Molecular Diagnostics

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Blood Protein Profile Indicates Early-Onset Coronary Heart Disease
New DNA Test Tracks Spread of Parasitic Disease from Single Sample
Hidden Blood Biomarkers to Revolutionize Diagnosis of Diabetic Kidney Disease
Image: Cancerguard is the only MCED test on the market to analyze multiple biomarker classes, enhancing early cancer detection (Photo courtesy of Exact Sciences)

Liquid Biopsy Test to Enable Earlier Diagnosis of Numerous Cancer Types

Routine screening currently covers only a handful of cancers, leaving most cases detected after symptoms appear—often at advanced stages when outcomes are poorer. A new study now suggests that adding a... Read more

Hematology

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Microvesicles Measurement Could Detect Vascular Injury in Sickle Cell Disease Pa...
ADLM’s New Coagulation Testing Guidance to Improve Care for Patients on Blood Th...
Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage
Image: Research has linked platelet aggregation in midlife blood samples to early brain markers of Alzheimer’s (Photo courtesy of Shutterstock)

Platelet Activity Blood Test in Middle Age Could Identify Early Alzheimer’s Risk

Early detection of Alzheimer’s disease remains one of the biggest unmet needs in neurology, particularly because the biological changes underlying the disorder begin decades before memory symptoms appear.... Read more

Immunology

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Blood-Based Liquid Biopsy Model Analyzes Immunotherapy Effectiveness
Signature Genes Predict T-Cell Expansion in Cancer Immunotherapy
Molecular Microscope Diagnostic System Assesses Lung Transplant Rejection
Image: The labyrinth chip could one day help doctors look for aggressive, stem-like cancer cells in patient blood (Photo courtesy of Joseph Xu/Michigan Engineering)

Chip Captures Cancer Cells from Blood to Help Select Right Breast Cancer Treatment

Ductal carcinoma in situ (DCIS) accounts for about a quarter of all breast cancer cases and generally carries a good prognosis. This non-invasive form of the disease may or may not become life-threatening.... Read more

Microbiology

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15-Minute Blood Test Diagnoses Life-Threatening Infections in Children
High-Throughput Enteric Panels Detect Multiple GI Bacterial Infections from Single...
Fast Noninvasive Bedside Test Uses Sugar Fingerprint to Detect Fungal Infections...
Image: Development of targeted therapeutics and diagnostics for extrapulmonary tuberculosis at University Hospital Cologne (Photo courtesy of Michael Wodak/Uniklinik Köln)

Blood-Based Molecular Signatures to Enable Rapid EPTB Diagnosis

Extrapulmonary tuberculosis (EPTB) remains difficult to diagnose and treat because it spreads beyond the lungs and lacks easily accessible biomarkers. Despite TB infecting 10 million people yearly, the... Read more

Pathology

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Hydrogel-Based Technology Isolates Extracellular Vesicles for Early Disease Diag...
AI Tool Improves Accuracy of Skin Cancer Detection
Highly Sensitive Imaging Technique Detects Myelin Damage
Image: Using the approach, the team visualized intricate neuronal networks across full human brain sections (Photo courtesy of Marios Georgiadis)

Simple Optical Microscopy Method Reveals Hidden Structures in Remarkable Detail

Understanding how microscopic fibers are organized in human tissues is key to revealing how organs function and how diseases disrupt them. However, these fiber networks have remained difficult to visualize... Read more

Technology

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AI-Powered Biosensor Technology to Enable Breath Test for Lung Cancer Detection
AI Model Achieves Breakthrough Accuracy in Ovarian Cancer Detection
Portable Biosensor Diagnoses Psychiatric Disorders Using Saliva Samples
Image: The technology can diagnose head and neck cancer early with a drop of saliva (Photo courtesy of Adobe Stock)

AI Saliva Sensor Enables Early Detection of Head and Neck Cancer

Early detection of head and neck cancer remains difficult because the disease produces few or no symptoms in its earliest stages, and lesions often lie deep within the head or neck, where biopsy or endoscopy... Read more

Industry

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Roche and Freenome Collaborate to Develop Cancer Screening Tests
Co-Diagnostics Forms New Business Unit to Develop AI-Powered Diagnostics
Qiagen Acquires Single-Cell Omics Firm Parse Biosciences
Image: Exact Sciences’ product lines feature advanced cancer screening and diagnostic solutions (Photo courtesy of Exact Sciences)

Abbott Acquires Cancer-Screening Company Exact Sciences

Abbott (Abbott Park, IL, USA) has entered into a definitive agreement to acquire Exact Sciences (Madison, WI, USA), enabling it to enter and lead in fast-growing cancer diagnostics segments.... Read more

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