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In Other News

Image: The Lacewing POC molecular platform can identify bacterial infections in less than 20 minutes using just a drop of blood (Photo courtesy of ProtonDx)

Blood-Based Diagnostic Method Could Identify Pediatric LRTIs

Lower-respiratory tract infections (LRTIs) are a leading cause of illness and death worldwide, and pneumonia is the leading infectious cause of death in children under five, claiming the lives of over 700,000 children each year globally. Read more
17 Dec 2025 | Microbiology
Image: Residual leukemia cells may predict long-term survival in acute myeloid leukemia (Photo courtesy of Shutterstock)

MRD Tests Could Predict Survival in Leukemia Patients

Acute myeloid leukemia is an aggressive blood cancer that disrupts normal blood cell production and often relapses even after intensive treatment. Read more
16 Dec 2025 | Hematology
Image: Determining EG spiked into medicinal syrups: Zoomed-in images of the pads on the strips are shown. The red boxes show where the blue color on the pad could be seen when visually observed (Arman, B.Y., Legge, I., Walsby-Tickle, J. et al. https://doi.org/10.1038/s41598-025-26670-1)

Rapid Low-Cost Tests Can Prevent Child Deaths from Contaminated Medicinal Syrups

Medicinal syrups contaminated with toxic chemicals have caused the deaths of hundreds of children worldwide, exposing a critical gap in how these products are tested before reaching patients. Read more
16 Dec 2025 | Pathology
Image: Using palmitic acid and ACSL1 alongside bile acids could improve early ICP diagnosis (Ruirui Dong et al., Biochim Biophys Acta Mol Cell Biol Lipids (2025). https://doi.org/10.1016/j.bbalip.2025.159692)

New Blood Biomarkers Help Diagnose Pregnancy-Linked Liver Complication

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder linked to pregnancy and can pose serious risks for both mother and baby, including premature delivery and stillbirth. Read more
16 Dec 2025 | Molecular Diagnostics
Image: Flowchart representing sample collections and small EV isolations from tissue, saliva, and plasma of HNC patients (A Jangholi et al., VIEW (2025). DOI: https://doi.org/10.1002/VIW.20250081)

Tumor Signals in Saliva and Blood Enable Non-Invasive Monitoring of Head and Neck Cancer

Head and neck cancers are among the most aggressive malignancies worldwide, with nearly 900,000 new cases diagnosed each year. Read more
16 Dec 2025 | Pathology
Image: Everyday health conditions can shape Alzheimer’s blood test results (Photo courtesy of Shutterstock)

Common Health Issues Can Influence New Blood Tests for Alzheimer’s Disease

Blood-based tests for Alzheimer’s disease are transforming diagnosis by offering a simpler alternative to spinal taps and brain imaging. Read more
15 Dec 2025 | Pathology
Image: The SAFE score successfully stratifies patients at risk of developing HCC (Tung-Hung Su et al.,Clinical and Molecular Hepatology (2025); doi.org/10.3350/cmh.2024.0822)

Blood Test Formula Identifies Chronic Liver Disease Patients with Higher Cancer Risk

Chronic liver disease affects millions worldwide and can progress silently to hepatocellular carcinoma (HCC), one of the deadliest cancers globally. Read more
15 Dec 2025 | Pathology
Image: Analysis of specific patterns of cfDNA fragmentation in urine samples can diagnose and stage bladder cancer (Herranz et al., The Journal of Molecular Diagnostics, DOI: 10.1016/j.jmoldx.2025.08.010)

Simple Urine Test to Revolutionize Bladder Cancer Diagnosis and Treatment

Bladder cancer is one of the most common and deadly urological cancers and is marked by a high rate of recurrence. Read more
12 Dec 2025 | Molecular Diagnostics
Image: The new device can be precisely tuned to sort cells across a range of sizes (Photo courtesy of Institute of Science Tokyo)

Tunable Cell-Sorting Device Holds Potential for Multiple Biomedical Applications

Isolating rare cancer cells from blood is essential for diagnosing metastasis and guiding treatment decisions, but remains technically challenging. Read more
12 Dec 2025 | Pathology
Image: FBLN5 detection in human hepatic stellate cells could act as an early warning sign of liver damage (Photo courtesy of Osaka Metropolitan University)

Blood Test to Enable Earlier and Simpler Detection of Liver Fibrosis

Persistent liver damage caused by alcohol misuse or viral infections can trigger liver fibrosis, a condition in which healthy tissue is gradually replaced by collagen fibers. Read more
12 Dec 2025 | Molecular Diagnostics
Image: The rapid sepsis test detected nearly three times more bloodstream infections than conventional blood cultures (Photo courtesy of Adobe Stock)

Rapid Diagnostic Test Matches Gold Standard for Sepsis Detection

Sepsis kills 11 million people worldwide every year and generates massive healthcare costs. In the USA and Europe alone, sepsis accounts for USD 100 billion in annual hospitalization expenses. Read more
11 Dec 2025 | Microbiology
Image: The newly discovered cells explain why some children with acute lymphoblastic leukemia do not respond well to treatment (Photo courtesy of Shutterstock)

Genetic Marker to Help Children with T-Cell Leukemia Avoid Unnecessary Chemotherapy

About 400 children in the UK are diagnosed with acute lymphoblastic leukemia (ALL) each year, with roughly 15% presenting with a more aggressive T-ALL subtype. Read more
11 Dec 2025 | Molecular Diagnostics
Image: An example output from the popEVE portal (Photo courtesy of Marks Lab)

Artificial Intelligence Model Could Accelerate Rare Disease Diagnosis

Identifying which genetic variants actually cause disease remains one of the biggest challenges in genomic medicine. Read more
11 Dec 2025 | Technology
Image: The 3D-printed dual-channel device separates protein and RNA signatures to reliably identify active HIV-1 infection (Photo courtesy of Penn State)

New Test Distinguishes Vaccine-Induced False Positives from Active HIV Infection

Since HIV was identified in 1983, more than 91 million people have contracted the virus, and over 44 million have died from related causes. Read more
10 Dec 2025 | Immunology

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Clinical Chemistry

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Mismatch Between Two Common Kidney Function Tests Indicates Serious Health Problems...
VOCs Show Promise for Early Multi-Cancer Detection
Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC...
Image: The ARi-FL fluorescent probe offers a clearer view of tumor behavior and treatment resistance (J. Med. Chem. 2025, 68, 15, 15812-15827)

Chemical Imaging Probe Could Track and Treat Prostate Cancer

Prostate cancer remains a leading cause of illness and death among men, with many patients eventually developing resistance to standard hormone-blocking therapies. These drugs often lose effectiveness... Read more

Molecular Diagnostics

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New PCR Test Improves Diagnostic Accuracy of Bacterial Vaginosis and Candida Vag...
New Serum Marker-Editing Strategy to Improve Diagnosis of Neurological Diseases
World’s First Genetic Type 1 Diabetes Risk Test Enables Early Detection
Image: A minimal four-gene host-response signature detected in blood can exclude bacterial respiratory infections (Photo courtesy of 123RF)

Four-Gene Blood Test Rules Out Bacterial Lung Infection

Lower respiratory tract infections (LRTIs) are among the most common reasons for antibiotic prescriptions, yet distinguishing bacterial infections from viral ones remains notoriously difficult.... Read more

Hematology

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Microvesicles Measurement Could Detect Vascular Injury in Sickle Cell Disease Pa...
ADLM’s New Coagulation Testing Guidance to Improve Care for Patients on Blood Th...
Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage
Image: Research has linked platelet aggregation in midlife blood samples to early brain markers of Alzheimer’s (Photo courtesy of Shutterstock)

Platelet Activity Blood Test in Middle Age Could Identify Early Alzheimer’s Risk

Early detection of Alzheimer’s disease remains one of the biggest unmet needs in neurology, particularly because the biological changes underlying the disorder begin decades before memory symptoms appear.... Read more

Immunology

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Chip Captures Cancer Cells from Blood to Help Select Right Breast Cancer Treatment...
Blood-Based Liquid Biopsy Model Analyzes Immunotherapy Effectiveness
Signature Genes Predict T-Cell Expansion in Cancer Immunotherapy
Image: The AI-powered genomic signature predicts poor response to CDK4/6 inhibitors in HR+/HER2– breast cancer (Photo courtesy of 123RF)

Gene Signature Test Predicts Response to Key Breast Cancer Treatment

DK4/6 inhibitors paired with hormone therapy have become a cornerstone treatment for advanced HR+/HER2– breast cancer, slowing tumor growth by blocking key proteins that drive cell division.... Read more

Microbiology

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Rapid Assay Identifies Bloodstream Infection Pathogens Directly from Patient Samples...
Blood-Based Molecular Signatures to Enable Rapid EPTB Diagnosis
15-Minute Blood Test Diagnoses Life-Threatening Infections in Children
Image: The TB-Feron point-of-care test detects latent tuberculosis infection within 15 minutes (Photo courtesy of SD Biosensor)

Rapid POC Tuberculosis Test Provides Results Within 15 Minutes

Tuberculosis remains one of the world’s deadliest infectious diseases, and reducing new cases depends on identifying individuals with latent infection before it progresses. Current diagnostic tools often... Read more

Pathology

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AI Tool Rapidly Analyzes Complex Cancer Images for Personalized Treatment
Diagnostic Technology Performs Rapid Biofluid Analysis Using Single Droplet
Novel Technology Tracks Hidden Cancer Cells Faster
Image: The AI tool can analyze abnormalities in the shape and form of blood cells (Simon Deltadahl et al. Nature Machine Intelligence (2025). DOI: 10.1038/s42256-025-01122-7)

AI Tool Outperforms Doctors in Spotting Blood Cell Abnormalities

Diagnosing blood disorders depends on recognizing subtle abnormalities in cell size, shape, and structure, yet this process is slow, subjective, and requires years of expert training. Even specialists... Read more

Technology

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AI-Powered Biosensor Technology to Enable Breath Test for Lung Cancer Detection
AI Model Achieves Breakthrough Accuracy in Ovarian Cancer Detection
Portable Biosensor Diagnoses Psychiatric Disorders Using Saliva Samples
Image: The technology can diagnose head and neck cancer early with a drop of saliva (Photo courtesy of Adobe Stock)

AI Saliva Sensor Enables Early Detection of Head and Neck Cancer

Early detection of head and neck cancer remains difficult because the disease produces few or no symptoms in its earliest stages, and lesions often lie deep within the head or neck, where biopsy or endoscopy... Read more

Industry

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Roche and Freenome Collaborate to Develop Cancer Screening Tests
Co-Diagnostics Forms New Business Unit to Develop AI-Powered Diagnostics
Qiagen Acquires Single-Cell Omics Firm Parse Biosciences
Image: Exact Sciences’ product lines feature advanced cancer screening and diagnostic solutions (Photo courtesy of Exact Sciences)

Abbott Acquires Cancer-Screening Company Exact Sciences

Abbott (Abbott Park, IL, USA) has entered into a definitive agreement to acquire Exact Sciences (Madison, WI, USA), enabling it to enter and lead in fast-growing cancer diagnostics segments.... Read more

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