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In Other News

Image: The 3D-printed dual-channel device separates protein and RNA signatures to reliably identify active HIV-1 infection (Photo courtesy of Penn State)

New Test Distinguishes Vaccine-Induced False Positives from Active HIV Infection

Since HIV was identified in 1983, more than 91 million people have contracted the virus, and over 44 million have died from related causes. Read more
10 Dec 2025 | Immunology
Image: A minimal four-gene host-response signature detected in blood can exclude bacterial respiratory infections (Photo courtesy of 123RF)

Four-Gene Blood Test Rules Out Bacterial Lung Infection

Lower respiratory tract infections (LRTIs) are among the most common reasons for antibiotic prescriptions, yet distinguishing bacterial infections from viral ones remains notoriously difficult. Read more
10 Dec 2025 | Molecular Diagnostics
Image: The cobas BV/CV assay enhances the capabilities of the cobas 5800/6800/8800 systems (Photo courtesy of Roche)

New PCR Test Improves Diagnostic Accuracy of Bacterial Vaginosis and Candida Vaginitis

Bacterial vaginosis (BV) impacts approximately 25% of women of reproductive age, while up to 75% of women experience candida vaginitis (CV) at least once in their lifetime. Read more
10 Dec 2025 | Molecular Diagnostics
Image: Shirin Nouraein is the first author on the study that led to the new serum marker-editing strategy (Photo courtesy of Jorge Vidal/Rice University)

New Serum Marker-Editing Strategy to Improve Diagnosis of Neurological Diseases

Tracking gene-expression changes in the brain is crucial for understanding neurological diseases, yet current monitoring tools are invasive or unable to capture subtle activity shifts over time. Read more
09 Dec 2025 | Molecular Diagnostics
Image: The TB-Feron point-of-care test detects latent tuberculosis infection within 15 minutes (Photo courtesy of SD Biosensor)

Rapid POC Tuberculosis Test Provides Results Within 15 Minutes

Tuberculosis remains one of the world’s deadliest infectious diseases, and reducing new cases depends on identifying individuals with latent infection before it progresses. Read more
09 Dec 2025 | Microbiology
Image: The T1D GRS Array uses patented Biochip array technology (Photo courtesy of Randox)

World’s First Genetic Type 1 Diabetes Risk Test Enables Early Detection

Type 1 Diabetes (T1D) affects more than eight million people worldwide, with numbers expected to rise sharply. Read more
09 Dec 2025 | Molecular Diagnostics
Image: The blood-based DNA methylation test predicts lymph node metastasis in early-stage gastric cancer (Photo courtesy of Institute of Science Tokyo)

Blood Test to Help Low-Risk Gastric Cancer Patients Avoid Unnecessary Surgery

Accurately identifying lymph node metastasis in early-stage gastric cancer remains a major clinical challenge. Read more
08 Dec 2025 | Molecular Diagnostics
Image: The AI tool can analyze abnormalities in the shape and form of blood cells (Simon Deltadahl et al. Nature Machine Intelligence (2025). DOI: 10.1038/s42256-025-01122-7)

AI Tool Outperforms Doctors in Spotting Blood Cell Abnormalities

Diagnosing blood disorders depends on recognizing subtle abnormalities in cell size, shape, and structure, yet this process is slow, subjective, and requires years of expert training. Read more
08 Dec 2025 | Pathology
Image: The EXENT System has received US FDA 510(k) clearance (Photo courtesy of Thermo Fisher)

First-Of-Its-Kind Automated System Speeds Myeloma Diagnosis

More than 176,000 people are diagnosed with multiple myeloma worldwide each year, yet the current diagnostic pathway can be slow and uncertain, often relying on a highly subjective interpretation of test results. Read more
08 Dec 2025 | Molecular Diagnostics
Image: The new analysis of blood samples links specific protein patterns to five- and ten-year mortality risk (Photo courtesy of Adobe Stock)

Blood Protein Profiles Predict Mortality Risk for Earlier Medical Intervention

Elevated levels of specific proteins in the blood can signal increased risk of mortality, according to new evidence showing that five proteins involved in cancer, inflammation, and cell regulation strongly predict long-term survival. Read more
05 Dec 2025 | Molecular Diagnostics
Image: SMMILe enables accurate spatial quantification in digital pathology using multiple-instance learning (Gao, Z et al. Nature Cancer, 2025; DOI: 10.1038/s43018-025-01060-8)

AI Tool Rapidly Analyzes Complex Cancer Images for Personalized Treatment

Complex digital biopsy images that typically take an expert pathologist up to 20 minutes to assess can now be analyzed in about one minute using a new artificial intelligence (AI) tool. Read more
05 Dec 2025 | Pathology
Image: The GASTROClear test for early detection of gastric cancer has an accuracy of 87% (Photo courtesy of MiRXES)

First Of Its Kind Blood Test Detects Gastric Cancer in Asymptomatic Patients

Each year, over 1 million people worldwide are diagnosed with gastric (stomach) cancer, and over 800,000 people die of the disease. Read more
05 Dec 2025 | Molecular Diagnostics
Image: The innovative diagnostic technology analyzes the full drying process of a blood droplet using machine learning (Photo courtesy of Anusuya Pal/The University of Tokyo)

Diagnostic Technology Performs Rapid Biofluid Analysis Using Single Droplet

Diagnosing disease typically requires milliliters of blood drawn at clinics, depending on needles, laboratory infrastructure, and trained personnel. Read more
04 Dec 2025 | Pathology
Image: The CryoViz cryo-imaging device (Photo courtesy of BioInVision)

Novel Technology Tracks Hidden Cancer Cells Faster

Targeting and treating disease often hinges on the ability to locate specific cells inside the body—a challenge made difficult because harmful or therapeutic cells move through tissues and are not easily detected. Read more
04 Dec 2025 | Pathology

Channels

Clinical Chemistry

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Mismatch Between Two Common Kidney Function Tests Indicates Serious Health Problems...
VOCs Show Promise for Early Multi-Cancer Detection
Portable Raman Spectroscopy Offers Cost-Effective Kidney Disease Diagnosis at POC...
Image: The ARi-FL fluorescent probe offers a clearer view of tumor behavior and treatment resistance (J. Med. Chem. 2025, 68, 15, 15812-15827)

Chemical Imaging Probe Could Track and Treat Prostate Cancer

Prostate cancer remains a leading cause of illness and death among men, with many patients eventually developing resistance to standard hormone-blocking therapies. These drugs often lose effectiveness... Read more

Molecular Diagnostics

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Benchtop Analyzer Runs Chemistries, Immunoassays and Hematology in Single Device...
POC Bordetella Test Delivers PCR-Accurate Results in 15 Minutes
Pinprick Blood Test Could Detect Disease 10 Years Before Symptoms Appear
Image: The compact, electricity-free molecular testing platform enables rapid STI detection at POC (Photo courtesy of Rapidemic)

Portable Molecular Test Detects STIs at POC in 15 Minutes

Sexually transmitted infections (STIs) such as Chlamydia trachomatis and Neisseria gonorrhoeae affect more than 370 million people annually, with women in low- and middle-income countries facing the greatest... Read more

Hematology

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Microvesicles Measurement Could Detect Vascular Injury in Sickle Cell Disease Pa...
ADLM’s New Coagulation Testing Guidance to Improve Care for Patients on Blood Th...
Viscoelastic Testing Could Improve Treatment of Maternal Hemorrhage
Image: Research has linked platelet aggregation in midlife blood samples to early brain markers of Alzheimer’s (Photo courtesy of Shutterstock)

Platelet Activity Blood Test in Middle Age Could Identify Early Alzheimer’s Risk

Early detection of Alzheimer’s disease remains one of the biggest unmet needs in neurology, particularly because the biological changes underlying the disorder begin decades before memory symptoms appear.... Read more

Immunology

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Chip Captures Cancer Cells from Blood to Help Select Right Breast Cancer Treatment...
Blood-Based Liquid Biopsy Model Analyzes Immunotherapy Effectiveness
Signature Genes Predict T-Cell Expansion in Cancer Immunotherapy
Image: The AI-powered genomic signature predicts poor response to CDK4/6 inhibitors in HR+/HER2– breast cancer (Photo courtesy of 123RF)

Gene Signature Test Predicts Response to Key Breast Cancer Treatment

DK4/6 inhibitors paired with hormone therapy have become a cornerstone treatment for advanced HR+/HER2– breast cancer, slowing tumor growth by blocking key proteins that drive cell division.... Read more

Microbiology

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Blood-Based Molecular Signatures to Enable Rapid EPTB Diagnosis
15-Minute Blood Test Diagnoses Life-Threatening Infections in Children
High-Throughput Enteric Panels Detect Multiple GI Bacterial Infections from Single...
Image: The SMART-ID Assay delivers broad pathogen detection without the need for culture (Photo courtesy of Scanogen)

Rapid Assay Identifies Bloodstream Infection Pathogens Directly from Patient Samples

Bloodstream infections in sepsis progress quickly and demand rapid, precise diagnosis. Current blood-culture methods often take one to five days to identify the pathogen, leaving clinicians to treat blindly... Read more

Pathology

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AI Tool Predicts Treatment Success in Rectal Cancer Patients
Blood Test and Sputum Analysis Predict Acute COPD Exacerbation
AI Tool to Transform Skin Cancer Detection with Near-Perfect Accuracy
Image: The AI system uses dual-resolution image analysis to identify breast cancer with greater precision than conventional AI tools (Photo courtesy of Shutterstock)

AI Tool Improves Breast Cancer Detection

Breast cancer diagnosis relies on examining microscopic tissue samples, a time-intensive process made more challenging by global shortages of trained pathologists. Delays in diagnosis can lead to missed... Read more

Technology

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AI-Powered Biosensor Technology to Enable Breath Test for Lung Cancer Detection
AI Model Achieves Breakthrough Accuracy in Ovarian Cancer Detection
Portable Biosensor Diagnoses Psychiatric Disorders Using Saliva Samples
Image: The technology can diagnose head and neck cancer early with a drop of saliva (Photo courtesy of Adobe Stock)

AI Saliva Sensor Enables Early Detection of Head and Neck Cancer

Early detection of head and neck cancer remains difficult because the disease produces few or no symptoms in its earliest stages, and lesions often lie deep within the head or neck, where biopsy or endoscopy... Read more

Industry

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Roche and Freenome Collaborate to Develop Cancer Screening Tests
Co-Diagnostics Forms New Business Unit to Develop AI-Powered Diagnostics
Qiagen Acquires Single-Cell Omics Firm Parse Biosciences
Image: Exact Sciences’ product lines feature advanced cancer screening and diagnostic solutions (Photo courtesy of Exact Sciences)

Abbott Acquires Cancer-Screening Company Exact Sciences

Abbott (Abbott Park, IL, USA) has entered into a definitive agreement to acquire Exact Sciences (Madison, WI, USA), enabling it to enter and lead in fast-growing cancer diagnostics segments.... Read more

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