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Liquid Biopsy Detects Lung Cancer Recurrence Signals Months Before Imaging

Multimodal Clinical Data Models Predict Cachexia Risk Across Cancers

Point-of-Care Blood Biomarker Test Detects Brain Injury Missed by CT

Daily Blood Testing May Help Guide Earlier Antibiotic Stopping in Sepsis

Qiagen Agrees to Go Private Through EQT-Led Acquisition

Multimodal Platform to Combine Blood and Imaging Biomarkers for Lung Nodule Assessment

Modeling Study Shows Blood-Based CRC Screening Could Prevent More Deaths Than Stool Tests

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30 Oct 2026 - 04 Nov 2026

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04 Nov 2026 - 08 Nov 2026

74th Annual Scientific Meeting of the American Society of Cytopathology (ASC)

05 Nov 2026 - 08 Nov 2026

24th Greek National Congress of Clinical Chemistry

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AI Approach Improves Brain MRI Lesion Detection in Epilepsy and Multiple Sclerosis

Implantable Ultrasound Device Enhances Local Drug Delivery in Glioblastoma

Chest Digital Twin Guides Light Therapy Dosing for Pneumonia

FDA-Cleared Thrombectomy System Removes Pulmonary Embolism Clots

Intraoperative Drug Combination Reduces Kidney Injury in Septic Shock Surgery

Microfluidic Assay Predicts Treatment Response in Pediatric Leukemia

Image: Device schematic and experimental workflow (Williams, E.K., Zhang, D.Y., Alese, T.T. et al. Nature Biomedical Engineering, 2026. https://doi.org/10.1038/s41551-026-01818-0)

A new lab-on-a-chip assay profiles responses to three-drug combinations in pediatric leukemia.
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29 Oct 2026

Blood-Based Small RNA Assay Predicts Survival After Lung Cancer Treatment

29 Oct 2026

AI Models Use Routine Blood Tests and Health Records to Predict Cancer Risk

29 Oct 2026

AI Pathology Approach Closely Aligns With Breast Cancer Genomic Risk Classification

29 Oct 2026

Donor-Derived DNA Testing May Reduce Biopsies in Kidney Transplant Monitoring

29 Oct 2026

Spinal Fluid Liquid Biopsy May Help Clarify Uncertain Brain Tumor Findings

28 Oct 2026

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In Other News

Image: Cytokine release syndrome (CRS) can occur following CAR T-cell therapy in patients with autoimmune disease. (Image Credit: Shutterstock)

Immune and Inflammatory Markers May Help Assess CAR T-Cell Complication Risk

New data link immune cell levels and inflammation to complication risk after CAR T-cell therapy for autoimmune disease. Read more
28 Oct 2026 | Immunology

Image: The automated IHC assay helps identify mesothelioma and distinguish it from other malignancies, including NSCLC. (Image Credit: Shutterstock)

Roche Launches Automated Test to Support Mesothelioma Differential Diagnosis

A new automated tissue-staining test improves mesothelioma diagnosis by distinguishing it from lung cancer and benign mimics while preserving tissue. Read more
28 Oct 2026 | Pathology

Image: The new myPanel custom SureSeq NGS panel detects AML-associated fusions and measures MECOM expression at MRD-level sensitivity in a single assay. (Photo courtesy of OGT)

New NGS Panel Detects AML Fusions at MRD-Level Sensitivity

A new NGS panel expands AML fusion detection at MRD-level sensitivity in a single assay. Read more
28 Oct 2026 | Molecular Diagnostics

Image: A new study identified 17 plasma proteins linked to mortality in older adults, several of which also track biological ageing across multiple organ systems. (Image Credit: Adobe Stock)

Blood Proteins Linked to Mortality Risk and Biological Aging Across Organ Systems

New data identify mortality-linked plasma proteins that track biological age across organs, refining prognostic markers. Read more
28 Oct 2026 | Clinical Chem.

Image: The OSOM COVID-19/Flu A&B Combo Test is a lateral flow immunochromatographic assay intended for the qualitative detection and differentiation of influenza A and influenza B nucleoprotein antigens and SARS-CoV-2 nucleocapsid antigen. (Photo courtesy of Sekisui Diagnostics)

COVID-19 and Flu Combo Test Launches With FDA Clearance

Sekisui Diagnostics has launched the 510(k)-cleared OSOM COVID-19/Flu A&B Combo Test for use in professional healthcare settings. Read more
28 Oct 2026 | Immunology

$Image: Distinct tau isoform signatures in Alzheimer\'s disease and amyotrophic lateral sclerosis. (Abu-Rumeileh, S., Großkopf, H., Guthknecht, A. et al. Nature Communications, 2026. DOI: 10.1038/s41467-026-78390-3)$

Two-Step Blood Test Improves Specificity for Alzheimer’s Diagnosis

A new two-step blood test isolates brain-derived tau, boosting p-tau217 specificity for Alzheimer’s and reducing false positives. Read more
28 Oct 2026 | Clinical Chem.

Image: Roche’s CE-marked cobas smart e immunoanalyser brings Elecsys immunoassay testing to smaller and decentralized laboratories in a compact benchtop platform. (Photo courtesy of Roche)

Compact Immunoanalyzer Gains CE Mark for Testing Across Local Care Settings

Roche has received the CE Mark for its compact cobas smart e immunoanalyser, designed for central-lab performance in under one square meter. Read more
28 Oct 2026 | Immunology

Image: The updated framework is intended for use in molecular diagnostic reports, tumor board discussions, clinical guidelines, and routine treatment planning (Image Credit: Shutterstock)

Updated Framework Guides Assessment of Actionable Cancer Biomarkers

ESMO has updated its ESCAT framework to help oncologists assess molecular alterations and match patients with targeted therapies. Read more
27 Oct 2026 | Molecular Diagnostics

Image Credit: Adobe Stock

Genomic Tissue Test Predicts Metastasis and Abiraterone Benefit in High-Risk Prostate Cancer

A tissue-based molecular test stratifies prostate cancer spread risk and identifies patients who may benefit from therapy.

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27 Oct 2026 | Molecular Diagnostics

Photo courtesy of Tempus AI

RNA Sequencing Assay Gains EU Certification for Solid Tumor Profiling

The Tempus xR assay has received certification under the EU’s IVDR as a Class C in vitro diagnostic device. Read more
27 Oct 2026 | Molecular Diagnostics

Image Credit: Adobe Stock

Decentralized Laboratory Network Improves Detection of Viral Hemorrhagic Fevers in Guinea

New findings show that sustained decentralized laboratories enable 24-hour viral hemorrhagic fever testing. Read more
27 Oct 2026 | Microbiology

Image: New research shows that human lung cancers use a process called alternative RNA splicing to produce different versions (isoforms) of the immune-alarm gene STAT2, shown here as ribbons. Isoforms of STAT2 are associated with how well lung cancer patients respond to immunotherapy: an isoform that retains an extra segment called an intron (top ribbon) is found in patients who respond to anti-PD-L1, while an isoform without it (bottom ribbon) is found in nonresponders. These splicing signatures could one day help doctors predict, before treatment begins, which patients are most likely to benefit from immunotherapy. (Photo courtesy of The Jackson Laboratory)

Lung Tumor RNA Variants Offer Clues to Immunotherapy Benefit

Researchers identify gene activity patterns linked to immunotherapy response in lung cancer. Read more
27 Oct 2026 | BioResearch

Image: Spleen tissue from a mouse without PHF19 (left) and a mouse with normal PHF19 function (right). Dense clusters of immune cells sit within blood-rich regions in pink. Without PHF19, cells are altered in their differentiation process (Photo courtesy of Gianni Gamarra/Centro de Regulación Genómica)

Six-Gene Score Improves Prognosis Prediction in Acute Myeloid Leukemia

Researchers identify a six-gene AML score that more accurately predicts survival and may simplify prognostic testing. Read more
26 Oct 2026 | Molecular Diagnostics

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Clinical Chemistry

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Image Credit: Shutterstock

Common Kidney Function Tests May Miss CKD in Cancer Patients

Chronic kidney disease (CKD) can complicate cancer care, as reduced kidney filtration may affect treatment eligibility and dosing. In oncology, kidney function assessment often relies on estimated glomerular... Read more

Image Credit: Adobe Stock

Point-of-Care Blood Biomarker Test Detects Brain Injury Missed by CT

Traumatic brain injury remains difficult to assess in emergency settings because some patients continue to have symptoms despite normal computed tomography findings. Approximately 2.8 million people in the U.... Read more

Daily Blood Testing May Help Guide Earlier Antibiotic Stopping in Sepsis

Sepsis is a life-threatening condition caused by the body’s overwhelming response to infection and accounts for thousands of deaths each year. In intensive care, concern about stopping treatment too early... Read more

Image: Blood proteins measured years before diagnosis may signal future prostate cancer risk, including aggressive disease.(Image Credit: iStock)

Blood Proteins Reveal Signals Linked to Prostate Cancer Risk Years Before Diagnosis

Prostate cancer is the most commonly diagnosed cancer in men worldwide. While many tumors grow slowly, aggressive forms can be life-threatening, underscoring the need for earlier risk identification.... Read more

Molecular Diagnostics

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Long-Read Sequencing Reveals Cancer-Driving Changes Missed by Conventional Testing

Cancer diagnosis often relies on identifying genomic alterations that influence tumor behavior and treatment selection. However, conventional short-read sequencing can miss complex DNA changes, leaving... Read more

Whole-Genome MRD Test Detects Traces of Cancer During and After Treatment

Small amounts of cancer can remain after treatment at levels that are difficult to detect, creating uncertainty about recurrence risk. Molecular residual disease (MRD) testing addresses this challenge... Read more

Molecular Vaginitis Panel Gains FDA Clearance and CLIA Waiver for Point-of-Care Use

Vaginitis affects most women at least once in their lifetime and can cause painful, disruptive symptoms. Common causes include bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis, reflecting... Read more

Image: AI-Based Stepwise Prediction Framework for Immunotherapy Response: A Machine-Learning Approach for Predicting Responders and Non-Responders Based on Tumor Cell Senescence (Photo courtesy of POSTECH)

AI Tool Predicts Immunotherapy Response Using Tumor Senescence Signals

Patients receiving the same cancer immunotherapy can have markedly different outcomes, with some showing little or no response. Identifying these patients earlier could reduce the costs of ineffective... Read more

Hematology

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New Risk-Stratification Tool Predicts Relapse After Blinatumomab in Childhood ALL

Acute lymphoblastic leukemia in children and young people requires careful assessment of relapse risk, particularly as treatment approaches move beyond standard chemotherapy. Traditional relapse predictors... Read more

New Myelofibrosis Guidelines Recommend Expanded Genetic Testing at Diagnosis

Myelofibrosis is a rare, life-threatening blood cancer affecting up to six per 100,000 people. The disease causes scarring in the bone marrow, limiting the production of healthy blood cells and potentially... Read more

Handheld Point-of-Care Test Aims to Enable Rapid Coagulation Assessment in Trauma

Severe blood loss and inadequate tissue oxygenation are leading causes of preventable death after traumatic injury. Blood products are essential in trauma care, but cold-chain storage, short shelf life,... Read more

Image Credit: Adobe Stock

New Donor Genetic Marker May Help Predict Stem Cell Transplant Success

Donor selection for hematopoietic stem cell transplantation plays a major role in relapse risk and survival for patients with blood cancers and other blood disorders. Despite advances in genotyping, uncertainty... Read more

Immunology

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Antibody Profiling Predicts Inflammatory Bowel Disease Years Before Diagnosis

Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, involves abnormal immune responses that cause persistent inflammation and damage in the digestive system.... Read more

Immune Profiling Initiative Aims to Improve Bone Marrow Analysis in Leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer in which assessing disease burden after therapy can help guide clinical evaluation. Patients with measurable residual disease (MRD) after treatment... Read more

Immune Profiling Identifies Early Maternal Autoantibodies Linked to Preterm Birth Risk

A typical pregnancy lasts about 40 weeks, but labor begins prematurely in roughly one in 10 pregnancies. Preterm birth is the leading cause of newborn death worldwide, yet its underlying causes and which... Read more

Image: Graphical Abstract (M. A. A. Kodydek, M. E. Reyna, A. Kothari, et al., “ IgE Sensitization Patterns of Mothers and Their Offspring in the First Five Years of Life The CHILD Study,” Allergy (2026): 1–11, https://doi.org/10.1111/all.70516)

Longitudinal Blood Testing Reveals Changes in Allergen Sensitization During Childhood

Food allergy is a major childhood health concern, and distinguishing persistent risk from transient sensitization can guide clinical decisions. Specific IgE antibodies may be detectable even when a child... Read more

Microbiology

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Molecular Panel Gains WHO Emergency Use Listing to Support Ebola Outbreak Response

The ongoing Ebola Bundibugyo outbreak in the Democratic Republic of the Congo and neighboring countries has become one of the largest outbreaks of this Ebola virus species recorded to date.... Read more

Rapid Host-Response Test Aims to Predict Corticosteroid Benefit in Sepsis

Sepsis and severe infections are difficult to treat because patients with similar clinical presentations may have very different underlying immune responses. Corticosteroids are commonly used in severe... Read more

Oral and Lung Microbiome Changes Linked to Severe Long Covid Symptoms

Long Covid can involve persistent respiratory, cognitive, and gastrointestinal symptoms after acute infection, creating a difficult diagnostic and management challenge. Because COVID-19 initially affects... Read more

Image: A health worker from the Mfou District Hospital collects a blood sample for the study (Photo courtesy of Sandrine Nsango, PhD)

Study Finds Distinct Malaria Parasites Linked to Sickle Cell Trait Protection

Malaria remains one of the world’s deadliest infectious diseases and has affected humans throughout recorded history. In regions where malaria is common, human genetics have been shaped by the sickle cell... Read more

Pathology

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Digital Pathology Test Stratifies Recurrence Risk in Early Breast Cancer

In hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative early breast cancer, accurate recurrence-risk assessment helps guide treatment decisions. However, individual risks... Read more

$Image: Ovarian cancer tissue image. (Photo courtesy of Heba Sailem/King\'s College London)$

AI Pathology Tool Predicts DNA Repair Deficiency in High-Grade Serous Ovarian Cancer

High-grade serous tubo-ovarian carcinoma is an aggressive cancer arising in the ovaries or fallopian tubes. Some tumors exhibit homologous recombination deficiency (HRD), a feature reflecting impaired DNA repair.... Read more

AI Tissue Analysis May Help Identify Missed Precancerous Colon Polyps

Colorectal cancer is diagnosed in an estimated 1.9 million people worldwide each year, often without symptoms in its early stages. Timely detection of precancerous lesions is therefore important, yet some... Read more

AI Pre-Screening Helps Identify Lung Cancer Cases for Additional Biomarker Testing

Tempus AI (Chicago, IL, USA) will present findings from a study evaluating an artificial intelligence (AI)-enabled pre-screening panel for advanced non-small cell lung cancer (NSCLC) at the ESMO Congress... Read more

Technology

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Compact PCR Thermal Cycler Launches for Routine Molecular Laboratory Workflows

Molecular laboratories rely on nucleic acid analysis to detect molecular information accurately and reproducibly across a wide range of applications. Supporting these routine workflows, a newly launched... Read more

New AI-Powered System Aims to Streamline Laboratory and Manufacturing Workflows

Scientific laboratories supporting drug development, biotechnology, and materials research increasingly rely on coordinated digital workflows to move data, samples, and activities across teams.... Read more

Laser-Based Swab Analysis Shows Promise for Detecting Disease-Linked Odor Patterns

Disease-related changes in volatile organic compounds can alter body odor, producing measurable patterns in exhaled breath and bodily fluids. Current analytical methods can be complex, time-consuming,... Read more

Image: Antibody-coated microscopic beads are introduced into a tiny flow channel containing blood plasma. Laser irradiation enhances their interaction with CEACAM-5, a colorectal cancer biomarker, causing the beads to assemble and generate a detectable signal. (Image Credit: Figure reproduced from Iida et al., Nanoscale Horizons(2026), DOI: 10.1039/d6nh00017g. Licensed under CC BY-NC 4.0.)

Laser-Enhanced Assay Boosts Sensitivity for Colorectal Cancer Biomarker Detection

Colorectal cancer is the third most commonly diagnosed cancer and the second leading cause of cancer-related death worldwide. Early detection remains critical, but cancer biomarkers can produce only faint... Read more

Industry

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Collaboration Brings Tumor-Informed MRD Monitoring to Breast Cancer Care in Abu Dhabi

For many patients, cancer treatment does not eliminate the risk of recurrence, which may occur months or years later and become harder to treat after spreading. Recurrence is often detected only after... Read more

Real Diagnostics Adds Saliva-Based Periodontal Testing With SimplyTest Deal

Real Diagnostics (Reisterstown, MD, USA) has acquired SimplyTest (Huntsville, AL, USA), a provider of saliva-based diagnostic tests for oral health. The acquisition adds the SimplyTest PERIO product to... Read more

Qiagen Agrees to Go Private Through EQT-Led Acquisition

QIAGEN N.V. (Venlo, the Netherlands) and EQT Private Equity (Stockholm, Sweden) have agreed to an all-cash public takeover offer for all outstanding QIAGEN shares at EUR 46.50 per share.... Read more

Hologic and Inpeco Partner to Advance Molecular Laboratory Automation in Europe

Hologic, Inc. (Marlborough, MA, USA) and Inpeco S.A. (Novazzano, Switzerland) have signed a co-marketing partnership in Europe for Inpeco’s recently launched FlexLab X automation solution and Hologic’s... Read more

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