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Molecular Immunohistochemical Profiling Identifies Invasive Breast Carcinoma

Molecular and immunohistochemical profiling of invasive micropapillary carcinoma of the breast was used to identify potentially useful markers for targeted therapies with a focus on a specific gene mutation.   More...
23 Oct 2014

Circulating Exosomes Analysis Uses Microfluidic Technology

A new microfluidic approach has been developed to streamline and expedite the exosome analysis pipeline by integrating specific immunoisolation and targeted protein analysis of circulating exosomes.  More...
23 Oct 2014
DRG International
DiagCor Bioscience
Image: A fluorescent proximity ligation assay of protein-protein interactions (Photo courtesy of Abnova).

Blood Test Determines Esophageal Cancer Patient Treatment Options

A blood test that may be beneficial in indicating neoadjuvant treatment regimens for patients with esophageal squamous cell carcinoma has been introduced.   More...
21 Oct 2014
Image: High magnification micrograph of focal segmental glomerulosclerosis (FSGS) (Photo courtesy of Wikimedia Commons).

Antibody Panel Predicts Risk of Organ Loss Prior to Kidney Transplantation

An ELISA test based on a panel of seven antibodies can help identify primary focal segmental glomerulosclerosis patients at high risk of recurrence before kidney transplantation. More...
21 Oct 2014
Image: Near-ultra violet induced autofluorescence shows significant differences between tumoral and healthy tissue (Photo courtesy of Dr. Geneviève Bourg-Heckly).

Biomarker Found for Epithelial Cancer Stem Cells

Tumors are mosaics of cells that are morphologically and molecularly very different and over the past years have been suggested to be responsible for the origin of cancer and for the resistance to conventional chemical therapies.  More...
20 Oct 2014
Life Technologies
Image: The HTS PAL autosampler (Photo courtesy of Leap Technologies).

Newly Discovered Marker Detects Early Pancreatic Cancer

A marker in the blood that may indicate early development of the pancreatic ductal adenocarcinoma could pave the way for an early detection test.  More...
17 Oct 2014
Image: GS3 prostate cancer: The tissue still has recognizable glands, but the cells are darker. At high magnification, some of these cells have left the glands and are beginning to invade the surrounding tissue or having an infiltrative pattern. This corresponds to a moderately differentiated carcinoma (Photo courtesy of Wikimedia Commons).

PSA Gene Variants Distinguish Patients with Highly Aggressive Prostate Cancer

Cancer researchers have identified three mutations in the KLK3 gene, which codes for prostate specific antigen, associated with biopsy-proven high-aggressive prostate cancer.  More...
16 Oct 2014

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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