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Pathology

Gene Involved In Hereditary Neuroendocrine Tumors Identified

To date, 11 main genes whose mutations are responsible for pheochromocytomas and paragangliomas have been identified and of these, 6 are involved in cellular metabolism, more specifically, the Krebs cycle, which is the machinery used by cells to burn oxygen and obtain the energy required for cellular work.   More...
22 Apr 2015
Image: Scanning electron micrograph of human prostate cancer cells (Photo courtesy of Dr. Gopal Murti).

Prostate Cancer Biomarker Gives Warning of Treatment Failure

A blood test that measures the number of cells shed from prostate tumors into the bloodstream can act as an early warning sign that treatment is not working.   More...
16 Apr 2015
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Image: Breast tissue computationally stained using data from infrared imaging without actually staining the tissue, enabling multiple stains on the same sample. From left, the image shows a Hematoxylin and Eosin stain (pink-blue), molecular staining for epithelial cells (brown color) and Masson\'s trichrome (blue, red at right) (Photo courtesy of Prof. Rohit Bhargava).

New Technique Paints Tissue Samples with Light

One infrared scan can give pathologists a window into the structures and molecules inside tissues and cells, enabling fast and broad diagnostic assessments, due to a newly developed imaging technique.  More...
16 Apr 2015
Image: Photomicrograph of a colon carcinoma shows architectural abnormalities that are even more severe than those of an adenoma (Photo courtesy of the University of Washington).

Biomarker Based Blood Test Detects Colorectal Cancer

A test is needed that offers greater certainty and that can detect bowel cancer at an early stage and at the same time reaches the whole population. Should this be achieved with a blood test, it might lower the reluctance seen in patients towards the stool test.   More...
15 Apr 2015

Likelihood of Lymphoma Recurrence Can Be Predicted by Monitoring Blood Levels of Circulating Tumor DNA

A recent paper described the measurement of circulating tumor DNA to diagnose patients with diffuse large B-cell lymphoma and to predict their likely response to treatment.   More...
15 Apr 2015
Image: Inhibitor of differentiation 4 positive (ID4+) stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye (Photo courtesy of Garvan Institute of Medical Research).

Gene Identified That Drives Aggressive Form of Breast Cancer

A gene has been identified that drives one of the most aggressive forms of breast cancer, giving hope that by finding a way to block the gene they may be able to make the cancer less aggressive.  More...
13 Apr 2015
Image: Histopathology of cribriform type ductal carcinoma in situ (DCIS) of the breast (Photo courtesy of Difu Wu).

Diagnostic Accuracy of Pathologists Interpreting Breast Biopsies Examined

Nearly one-quarter of breast biopsies demonstrate invasive breast cancer, the majority are categorized by pathologists according to a diagnostic spectrum ranging from benign to pre-invasive disease.   More...
07 Apr 2015


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
 
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