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Image: A photomicrograph of a histological section of Benign Prostatic Hyperplasia, a non-cancerous condition of the prostate gland. The hyperplastic glands have papillary-like infoldings, with a myoepithelial cell layer (small nuclei near basement membrane) (Photo courtesy of Getty Images).

Urinary Volatiles Tested for Prostate Cancer Diagnosis

Early detection is one of the most important factors in helping men to survive prostate cancer, but the diagnosis is not straightforward. It usually relies on a combination of a digital rectal exam and a blood test to measure prostate-specific antigen (PSA) to help decide whether a biopsy should be done. More...
21 Apr 2017
Image: A histology of a fine needle aspiration of a lung lesion showing a three-dimensional cluster of cells with the nuclear changes of malignancy: variation in nuclear size, staining and shape, and features of squamous differentiation: moderate amount of cytoplasm, small/indistinct nucleoli, nucleus in the cell center, and keratinization (Photo courtesy of Nephron).

Blood Test Shows Cancer Recurrence Months before Scans

A prospective clinical trial showed that a blood test looking at specific biomarkers was able to detect recurrences of lung cancer an average of six months before conventional imaging methods found evidence of recurrence. More...
12 Apr 2017
Image: The cumulative incidence of dementia according to lipid concentrations (triglycerides, HDL-C, LDL-C, total cholesterol) (Photo courtesy of the University of Bordeaux).

Plasma Lipids Associated Differently with Dementia Incidents

Dementia refers to a group of neurological disorders characterized by memory loss, cognitive impairment, and disability in activities of daily living. As the primary risk factor for dementia is old age, the prevalence of dementia is increasing dramatically with aging populations worldwide. More...
12 Apr 2017
Image: A representation of the molecular structure of KDR (kinase insert domain receptor) protein (Photo courtesy of Wikimedia Commons).

Targeted Microbubbles Enhance Ultrasound Detection of Malignant Tumors

By combining standard ultrasound technology with a novel type of targeted microbubbles, cancer researchers have developed a sensitive method for detecting malignant tumors that could reduce the number of biopsies needed to differentiate them from benign growths. More...
11 Apr 2017
Image: A molecular model of human papillomavirus (HPV) (Photo courtesy of Wikimedia Commons).

Mutations Linked to Improved Survival of Patients with HPV+ Carcinoma

Cancer researchers analyzed head and neck squamous cell carcinoma (HNSCC) data from The Cancer Genome Atlas to identify molecular characteristics of human papillomavirus (HPV)+ HNSCC and correlated them with patient outcomes. More...
11 Apr 2017
Image: Microfluidic rare-cell workflow for multiplexed western blotting of single patient-derived CTCs (Photo courtesy of University of California – Berkeley).

CTC Protein Expression Uses Microfluidic Western Blotting

Circulating tumor cells (CTCs) are rare tumor cells found in the circulatory system of certain cancer patients and the clinical and functional significance of CTCs is still under investigation. More...
06 Apr 2017
Image: The LSM510 META confocal microscope (Photo courtesy of Zeiss).

Technology Developed for Prostate Cancer Diagnosis and Monitoring

Early diagnosis of prostate cancer and evaluation of appropriate treatment options requires development of effective and high-throughput selective capture technology for exosomes that are positive for the expression of enzyme-biomarker, prostate-specific membrane antigen (PSMA). More...
06 Apr 2017

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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