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Pathology

Circulating Cell-Free Nucleosomes Biomarkers Confirmed for Cancer Blood Tests

Studies have shown substantially improved overall survival among individuals screened for colorectal cancer (CRC), which is explained by diagnosis of early stages and prevention of CRC by endoscopic removal of precancerous lesions. More...
30 Jun 2016
Image: The therascreen EGFR RGQ PCR Kit is an automated molecular assay designed to detect the presence of mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC) (Photo courtesy of Qiagen).

Liquid Biopsy Urine Test Detects Mutations In Lung Cancer

While lung cancer is one of the most aggressive malignancies, progress has been made in the advancement of therapeutic strategies against the disease and in particular, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). More...
29 Jun 2016
Image: A micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. H&E stain. The dark purple (center) is lymphocytes (part of a normal lymph node). Surrounding the lymphocytes and extending into the surrounding fat (top of image) is ductal breast carcinoma (Photo courtesy of Michael Bonert / Wikimedia).

Artificial Intelligence Achieves Near-Human Performance in Image Analysis

A research team has developed an artificial intelligence (AI) method that trains computers to interpret pathology images. In a recent test of the method developed to examine images of lymph nodes, human complemented with computer analyses together identified breast cancer with 99.5% accuracy. More...
27 Jun 2016

Wide-ranging Genomic Study Links Migraine-Related Genes to the Vascular System

Results from 22 genome-wide association (GWA) studies conducted by dozens of researchers worldwide suggest that migraine is linked to specific gene loci that are associated with some vascular disease or are involved in the regulation of vascular tone. More...
27 Jun 2016
Image: The MammaTyper in vitro diagnostic test kit for breast cancer subtyping (Photo courtesy of BioNTech Diagnostics).

PCR Better at Identifying Breast Tumor Subtypes than Immunohistochemistry

A recently published study suggested that a RT-qPCR (reverse transcription quantitative real-time polymerase chain reaction) assay was superior to classical immunohistochemistry for subtyping breast tumors. More...
27 Jun 2016

T-Cell Receptor Sequencing Reveals Novel Biomarkers For Ovarian Cancer

Deep T-cell receptor (TCR) sequencing has been used to evaluate the clonal composition of tumor-infiltrating lymphocytes and identify novel prognostic biomarkers in ovarian cancer. More...
22 Jun 2016

Peripheral Blood Eosinophilia Correlates with Hyperplastic Nasal Polyp Growth

A reliable way to track the course of nasal polyps in chronic sinus disease, maybe linked to rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery. More...
22 Jun 2016


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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