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Image: Immunostaining of human lung tissue, fixed with HOPE, from a patients suffering from legionnaire\'s disease. One legionella protein (red-brown), the bacteria-containing vacuoles and individual legionella inside the scavenger cells can be detected. The infection process can be observed immediately using proteomics (Photo courtesy of Braunschweig University of Technology).

Novel Method Prepares Tissue Samples for Analyzing Proteins

A new way of preparing patient tissue for analyses might soon become the new standard, possibly replacing tissues fixed with formalin, before they are embedded in wax-like paraffin and cut into razor-thin slices.  More...
23 Apr 2014

Blood Test Provides Rapid Method of Detecting Solid Cancers

Circulating tumor DNA is a promising biomarker for noninvasive assessment of cancer burden, but existing detection methods have insufficient sensitivity or patient coverage for broad clinical applicability.  More...
22 Apr 2014
Image: The Infinium HumanMethylation27 BeadChip Kit uses the Infinium Methylation Assay and is compatible with the iScan, HiScan, and Bead Array Reader systems (Photo courtesy of Illumina).

Methylated DNA Blood Test Monitors Breast Cancer Progress and Treatment Response

An advanced assay that measures DNA hypermethylatation in blood samples can diagnose advanced breast cancer, as well as monitor tumor burden and treatment response in women with metastatic breast tumors.   More...
21 Apr 2014

Novel Biomarker Identified for Two Different Cancers

A new biomarker linked to better outcomes for patients with head and neck cancers and non-small-cell lung cancer has been identified.   More...
17 Apr 2014

Imaging and Blood Test Work Together to Optimize Evaluation of Ovarian Cancer Risk

A new US Food and Drug Administration-cleared blood test that measures the levels of five proteins and then uses a proprietary algorithm and software to calculate a single risk score has been the topic of recent research comparing the test to two imaging modalities.  More...
15 Apr 2014

American Diagnostic Laboratory Offers Genetic Test for Calreticlin Gene Mutations

A new diagnostic test that detects mutations in the gene encoding for the protein calreticulin is expected to help physicians identify patients with certain types of myeloproliferative neoplasms, which are blood cancers that have the potential to evolve into acute leukemia.  More...
14 Apr 2014

A Specific Mutation Links Some Forms of Inherited Melanoma

A mutation that inactivates the POT1 gene has been linked to the development of an inherited form of melanoma.  More...
09 Apr 2014

The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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