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Pathology

Genetic Mutations Linked to Rare Multiple Bowel Tumors

Most people with colorectal cancer will develop one primary tumor, which may then multiply and spread; however, in around 2% to 5% of colorectal cancer (CRC) cases, two primary tumors will originate and develop independently, known as synchronous colorectal cancer. More...
28 Jul 2016
Image: The Quickplex SQ 120 plate reader for electrochemiluminescence analyses (Photo courtesy of Meso Scale Discovery).

New Methods Detect Early Onset of Alzheimer's Disease

New methods to examine the brain and spinal fluid heighten the chance of early diagnosis of Alzheimer's disease and this may have important implications for early detection of the disease, the choice of drug treatment and the inclusion of patients in clinical trials. More...
28 Jul 2016
Abbott Diagnostics
Image: The DM4000 B automated LED microscope system (Photo courtesy of Leica Microsystems).

Bacterial Infection Identified as Cause of Overactive Bladder Syndrome

Overactive Bladder (OAB) is currently characterized by symptoms of urgency, with or without urgency incontinence, with increased frequency, and nocturia, and in some cases pain, in the absence of urinary tract infection (UTI) or other defined underlying pathology. More...
28 Jul 2016
Image: A whole-slide scanner with OlyVIA software (Photo courtesy of Olympus).

Simple Method Developed to Characterize Immune Cells in Tumors

Despite recent achievements in the development of cancer immunotherapies, only a small group of patients typically respond to them and therefore predictive markers of disease course and response to immunotherapy are urgently needed. More...
27 Jul 2016
Image: A radiograph of osteonecrosis of the right hip. Note the alternating areas of sclerosis and lucency in the femoral head. There are areas of collapse within the head as well as mild degenerative changes on the acetabular side (Photo courtesy of Dr. Brett Levine, MS, MD, and Dr. William Jaffe, MD).

New Genetic Mutation Linked to Osteonecrosis of the Hip

Osteonecrosis or 'bone death' of the femoral head is a disease caused by interruption of blood flow in the hip bone and patients, many of whom are under the age of 25, experience pain and the bone and surrounding joint collapse. More...
27 Jul 2016
Image: The framework of cancer metastases detection (Photo courtesy of Andrew Beck / BIDMC).

AI Approximates Human Performance in Breast Cancer Diagnosis

Artificial intelligence (AI) methods that train computers to interpret pathology images could make pathologic diagnoses more accurate. More...
25 Jul 2016
Image: The new BRIM technology enables pathologists to identify whether a DCIS is aggressive or not. In this image of a DCIS sample, the biomarkers CD44hi/CD24lo, reveals intraductal cells of aggressive cancer that are highlighted (Photo courtesy of University of Michigan Health System).

Aggressive Breast Cancer Identified with Fluorescent Technique

Ductal carcinoma in situ (DCIS) of the breast is the most common type of non-invasive breast cancer and in DCIS, epithelial cells proliferate within ducts, which are surrounded by a double layer of myoepithelial cells and basement membranes. More...
21 Jul 2016


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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