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Image: Culture of Clostridium difficile from a stool sample after 24 hours of incubation on chromogenic medium forming typical black colonies (Photo courtesy of the Freeman Hospital).

Stability of Fecal Specimens for Bacterial Diagnostics Investigated

 To test for Clostridium difficile in stool specimens transported from remote geographic locations is a challenge due to long transit times, often at room temperature. More...
23 Oct 2014
Image: A commercial Fabry–Pérot interferometer or etalon (Photo courtesy (United Scientific Supplies).

New Low-Cost Technique Detects Rotavirus

A new measurement method that increases the capacity to detect biological substances such as Rotavirus using optical biosensors has been discovered and patented.   More...
22 Oct 2014
Image: Scanning Electron Micrograph of Streptococcus pneumoniae by R. Facklam, J. Carr. Cerebrospinal fluid (CSF) β-2 transferrin detection decreases after inoculation with live or ciprofloxacin-inactived S. pneumoniae. This may be due to passive adsorption via distinctive features of the S. pneumoniae cell wall not present in the other bacterial species examined (Photo courtesy of MicrobeWiki and the CDC – [US] Centers for Disease Control and Prevention).

Infection Can Lead to False Negatives for Cerebrospinal Fluid β-2 Transferrin

Researchers have found that the presence of Streptococcus pneumoniae in cerebrospinal fluid can lead to false-negative β-2 transferrin test results and misdiagnosis that may detrimentally affect healthcare decisions for patients.  More...
21 Oct 2014
Image: The Diagnostics Respiratory Pathogens 21 PLUS (FTDRP) multiplex real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay kit (Photo courtesy of Fast-track Diagnostics).

Respiratory Viruses Detected by Sensitive Molecular Technique

Virologists at the Universidade Federal do Espírito Santo collected nasopharyngeal aspirates from 162 patients of all ages who were attended at either emergency rooms or primary care units between August 2007 and August 2009.  More...
16 Oct 2014

Shotgun Metagenomic Technique Detects Tuberculosis Bacteria in Patient Samples Without Culture or Enrichment

Infectious disease researchers have developed a new approach for the diagnosis of tuberculosis that relies on shotgun metagenomics, a method for direct sequencing of DNA extracted from sputum samples, which detects and characterizes the Mycobacterium that cause TB without the need for time-consuming culture or enrichment. More...
15 Oct 2014
Image: The agglutination latex assay for enteropathogenic and enterohemorrhagic Escherichia coli; negative (-) and a semi-quantitative positive (from + to ++++) agglutination pattern with anti-EspB monoclonal coated beads (Photo courtesy of Instituto Butantan).

Rapid Agglutination Latex Test Developed for Diarrheagenic Pathogens

Enteropathogenic and enterohemorrhagic Escherichia coli are human intestinal pathogens responsible for diarrhea in both developing and industrialized countries.  More...
09 Oct 2014

Biomarker Correlates With Survival for Pediatric Ebola Patients

Outbreaks of Ebola virus disease occur sporadically in Africa and are associated with high case-fatality rates yet children have been less affected than adults.  More...
09 Oct 2014

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