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Image: A photomicrograph of a bone marrow aspiration biopsy showing drug-induced agranulocytosis (Photo courtesy of NMH).

Genetic Test Predicts Adverse Reaction To Toxic Goiter Treatment

Agranulocytosis is an acute condition involving a severe and dangerous leukopenia or lowered white blood cell count and drug-induced agranulocytosis is a potentially life-threatening adverse reaction, and adverse drugs reactions are a leading cause of admission to hospital. More...
26 May 2016

Novel Technology Detects Blood Clots With Simple POC Test

Patients with cardiovascular disease, hypertension, atrial fibrillation, congestive heart failure, kidney disease and others who are at risk for blood clotting are especially vulnerable when blood-thinning medication levels get too weak or too strong. More...
25 May 2016
Image: A bone marrow aspirate biopsy of a patient with Gaucher Disease; the cytoplasm has wrinkled tissue paper appearance (Photo courtesy of the American Society of Hematology).

Elevated Chitotriosidase Differentially Diagnoses Lysosomal Storage Disorders

Plasma chitotriosidase originates from activated macrophages and is reported to be elevated in many Lysosomal Storage Disorders. Measurement of this enzyme’s activity has been an available tool for monitoring therapy of Gaucher disease. More...
25 May 2016

Gut Microbiome Pretreatment Predicts Chemotherapy-Related Bloodstream Infection

Bacteria are thought to enter the bloodstream through intestinal lesions due to chemotherapy-induced inflammation of the membrane lining the digestive tract. Once the infection begins, patients' own immune systems are depleted and are often unable to fight off the pathogens and antibiotics are often ineffective. More...
19 May 2016
Image: The Mirasol pathogen reduction technology for blood transfusions (Photo courtesy of Terumo BCT).

Blood Transfusions in Malaria Zones Made Safer

Patients, especially children, who undergo blood transfusions in sub-Saharan Africa, are at high risk of transfusion-transmitted malaria. Every year, approximately 214 million people worldwide are infected with acute malaria, the majority of whom are in Africa and the disease is caused by the parasite Plasmodium. More...
03 May 2016
Image: The BD LSR II benchtop flow cytometer (Photo courtesy of Becton Dickinson).

Blood Processing Methods Affect Microparticles Linked To Transfusion Reactions

Specific red blood cell manufacturing methods may be less damaging to cells than others and knowledge of this could help reduce adverse reactions in transfusion recipients and may impact the future of how blood is collected around the world. More...
29 Apr 2016
Image: The Axiovert 40 fluorescent microscope (Photo courtesy of Zeiss).

Novel Method Creates Megakaryocytes From Stem Cells For Transfusion

The production of megakaryocytes (MKs), the precursors of blood platelet, from human pluripotent stem cells (hPSCs) offers exciting clinical opportunities for transfusion medicine. Up to four components can be derived from donated blood: red cells, white cells, plasma and platelets. More...
28 Apr 2016

The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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