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Molecular Diagnostics

Image: Findings show that ctDNA testing may help identify candidates for radiotherapy and refine management by signaling when a cancer has changed or developed resistance (image credit: 123RF)

ctDNA Blood Test Could Help Guide Radiotherapy in Patients with Limited Metastases

A circulating tumor DNA (ctDNA) blood test could help select and monitor oligometastatic patients for radiotherapy. More...
18 May 2026
Image: Signatera CDx uses ctDNA analysis to identify residual tumor-derived genetic material after definitive treatment (image credit: Adobe Stock)

FDA-Approved MRD Blood Test Guides Adjuvant Bladder Cancer Therapy

Natera’s Signatera CDx has been approved by the U.S. FDA as a companion diagnostic for use with adjuvant atezolizumab in MIBC. More...
18 May 2026
Image: Findings show that genetic changes inside cancer cells may help explain why some patients with gallbladder cancer have poorer outcomes despite similar treatment (image credit: 123RF)

Tumor Genomic Profiling Identifies High-Risk Gallbladder Cancer

New findings link actionable tumor DNA alterations to shorter survival in gallbladder cancer, informing risk stratification. More...
18 May 2026
Image: The study frames predictive genomic screening as both a clinical opportunity and a systems challenge (photo courtesy of Mayo Clinic)

Genome Sequencing Uncovers Hidden Genetic Risks in Healthy Adults

Predictive genome sequencing in healthy adults uncovers hidden actionable risks and defines workflows to enable care. More...
18 May 2026
Image: FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate (Zhao, J., Yao, J., Hosseini, H., et al. Histopathology (2026). doi.org/10.1111/his.70166)

Sensitive Protein Marker Aids Diagnosis of Small Cell Prostate Cancer

Researchers have identified a sensitive protein marker aiding diagnosis of  difficult-to-classify prostate tumors. More...
15 May 2026
Image: Cepheid’s Xpert GI Panel has received CE marking under tIVDR, providing fast and accurate detection of 11 clinically relevant gastrointestinal pathogens from a single patient sample (photo ccourtesy of Cepheid)

Rapid Multiplex PCR Test Detects 11 Gastrointestinal Pathogens from Single Sample

A new multiplex PCR panel detects 11 GI pathogens from a stool sample in about 74 minutes to guide timely management. More...
15 May 2026
Image: Comparison of conventional B-cell acute lymphoblastic leukemia (B-ALL) fusion diagnostics (top) and Nanopore-based fusion detection (bottom) (Lin J, Opoku K, Litzow M, et al. J Mol Diagn. 2026. doi: 10.1016/j.jmoldx.2026.01.007)

Novel Algorithm Improves Detection of B-ALL Gene Fusions

A new algorithm improves gene fusion detection from long-read sequencing in B-cell acute lymphoblastic leukemia. More...
15 May 2026
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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