Features | Partner Sites | Information | LinkXpress
Sign In
SIEMENS DIAGNOSTICS

Nucleic Acid Test Rapidly Detects Antibiotic Resistant Staphylococcus

By Labmedica International staff writers
Posted on 02 Jan 2012
A rapid, accurate molecular diagnostic tool can differentiate two important disease-causing Staphylococcus bacteria, while simultaneously determining antibiotic resistance.

The Verigene automated BC-S test provides detection of Staphylococcus aureus, S. epidermidis, and the mecA gene. The mecA gene confers resistance to the antibiotic methicillin/oxacillin. Methicillin-resistant S.aureus (MRSA) bacteremia is associated with a significantly higher mortality rate than methicillin-susceptible S. aureus bacteremia, posing a substantial healthcare burden.

The BC-S test provides species and resistance detection from two types of Gram-positive blood culture bottles within two and a half hours, as compared with current microbiological culture methods, which can take up to 3 days.

Studies have shown that delayed administration of appropriate antibiotics is associated with a 7.6% decrease in survival rate for each hour that therapy is delayed. Rapid molecular testing of blood cultures has been shown to reduce this time, and is associated with hospital cost savings of up to USD 21,000 per patient.

A product of Nanosphere (Alachua, FL, USA), the BC-S test obtained CE-IVD marking for regulatory approval of the full BC-GP test as an in vitro diagnostic in Europe. It has now also received 510(k) clearance from the US Food and Drug Administration (FDA; Silver Spring, MD, USA) as the first phase of a stepwise process to obtain clearance for a larger test panel, which will be marketed as the Verigene BC-GP test.

The BC-S test expands Nanosphere's infectious disease test capabilities to include the rapid detection of bacteria that cause deadly bloodstream infections.

Related Links:

Nanosphere
US Food and Drug Administration




comments powered by Disqus

Channels

Immunology

view channel
Image: The fluorescence-activated cell sorting FACSCanto II flow cytometer (Photo courtesy of BD Biosystems).

Flow Cytometry Detects Lymphoproliferative Disorders in Fluid Specimens

Immunophenotypic analysis of hematopoietic cell populations by flow cytometry has emerged as a useful ancillary study in the diagnostic evaluation of serous effusions and cerebrospinal fluids (CSFs).... Read more

Lab Tech.

view channel
Image: A technical breakthrough for DNA imaging has been achieved that should quicken diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various pre-natal conditions (Photo courtesy of McGill University and Génome Québec Innovation Center).

Breakthrough DNA Analysis Technology to Hasten Problem Diagnosis

Researchers have achieved a technical breakthrough that should result in speedier diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various... Read more

Industry News

view channel

Most IVD Sector Companies Look Outside the EU and USA for Growth

Kalorama Information (New York City, NY, USA) has now published the 9th edition of its biennial market research report “Worldwide Market for In Vitro Diagnostics,” revealing estimates from its survey of the in vitro diagnostics (IVD) industry – presenting the trends, technologies, customer needs, and major suppliers with... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.