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Immunology

Image: Schematic of Mpox diagnostic methods.(A) Artificial intelligence (AI)-enhanced image classification can be leveraged to classify lesions concerning for Mpox, particularly in low resource settings where specialists (i.e., infectious disease specialists or dermatologists) are not available. (B) Clinical specimens (including nasal swabs, lesion swabs, or serum samples) can be used for molecular or biochemical confirmation of Mpox infection. (C) Rapidly, field-deployable devices or assays can be developed using various strategies(Mpox) diagnostic methods (Yilgic D, Ergonul O, Tasoglu S. Mpox diagnosis at POC. Trends in Biotechnology. DOI: 0.1016/j.tibtech.2025.04.015)

Point-of-Care Tests Could Expand Access to Mpox Diagnosis

New findings outline POC Mpox tools combining AI lesion triage with rapid assays to speed near-patient detection. More...
04 May 2026
Image: Graphical abstract (Turano PS, Akbulut E, Dewald HK, et al. Cell Reports (2026). DOI: 10.1016/j.celrep.2025.116795)

T-Cell Senescence Profiling May Predict CAR T Responses

New findings link T-cell senescence signatures to CAR T outcomes, supporting pre-manufacturing profiling to predict nonresponders. More...
04 May 2026
Photo courtesy of Volition

Finger-Prick Lateral Flow Test Detects Sepsis Biomarkers at Point of Care

A new finger-prick lateral flow prototype detects nucleosomes at the point of care, enabling faster sepsis risk assessment. More...
30 Apr 2026
Image: New findings underscore limitations of current two-tiered diagnostics in early Lyme Disease infection and point to a need for improved medical education on test interpretation (photo courtesy of Shutterstock)

Study Highlights Low Sensitivity of Current Lyme Tests in Early Infection

New data show two-tiered Lyme serology has low early sensitivity despite high specificity, urging cautious interpretation. More...
28 Apr 2026
Image: The findings show that patients with tumors harboring active networks of cytotoxic T cells were more likely to benefit from treatment, whereas those with dense clusters of plasma cells were significantly less likely to respond (photo courtesy of Shutterstock)

Tumor Immune Structure Predicts Response to Immunotherapy in Melanoma

New findings show spatial immune 'cellular neighborhoods' predict response to combination immunotherapy after anti-PD-1 failure. More...
24 Apr 2026
Image: Graphical abstract - Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence (photo courtesy of Zhang Weiqi)

Immune Aging Clock Quantifies Immunosenescence and Identifies Therapeutic Target

A new immune aging clock achieves a mean absolute error of 5.66 years in predicting chronological age. More...
20 Apr 2026
Image: Cancer hallmarks, molecular classes of iCCA, and therapies (Josep M. Llovet et al, Cell (2026). DOI: 10.1016/j.cell.2026.03.001)

Framework Guides Targeted and Immunotherapy Selection in Liver Cancer

A new framework review maps liver tumor hallmarks to targeted and immunotherapy options, guiding patient stratification. More...
20 Apr 2026
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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