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Clinical Chemistry

Image: Gross pathology of a cross section of a lung from an asthmatic with obstruction of major airways or bronchi (Photo courtesy of the University of New South Wales).

Urine Test Ensures Asthmatic Children Receive Appropriate Treatment

A new urine test could help ensure asthmatic children receive the level of medication they need to manage their illness better and prevent future asthma attacks.  More...
15 Dec 2014
Image: The composition of High-Density Lipoprotein Cholesterol (Photo courtesy of the University of California Davis).

Cardiovascular Risk Predicted by Test Measuring HDL Proteins

A new laboratory test has been developed that measures the presence of certain proteins in the High-Density Lipoprotein complex that can lead to an increased risk of cardiovascular disease and mortality.  More...
10 Dec 2014
DiagCor Bioscience
Image: The AirSense is a mass spectrometer based on the patented Ion-Molecule Reaction (IMR-MS) and can be used for a broad field of applications (Photo courtesy of V&F).

Simple Breath Test Aids Type 1 Diabetes Early Diagnosis

A chemical marker has been identified for type 1 diabetes in the breath of children who are unaware they have the condition until they develop diabetic ketoacidosis, a potentially life-threatening complication and a breath test could pave the way to allow early diagnosis.  More...
09 Dec 2014

Improved Assay Determines d-Xylose in Urine and Serum

A simple method for the evaluation of intestinal lactase activity in vivo has been developed and optimized in humans with potential advantages over current tests for the noninvasive diagnosis of lactase deficiency or hypolactasia.  More...
04 Dec 2014
Image: Molecular structure of apoE2. The amino acid argenine at site158 has been replaced by cysteine (Photo courtesy of Wikimedia Commons).

Cholesterol Levels in Later Life Depend in Part on Apolipoprotein E Allele Status

Variations in the APOE gene modify the rise and fall of serum cholesterol levels from midlife to late life, and in order to efficiently modify cholesterol through the life span, it is important that the physician takes into account the patient's APOE allele status.  More...
02 Dec 2014
Sekisui Diagnostics

Sickle Cell Trait Linked to Chronic Kidney Disease Risk

Sickle cell trait is defined as inheritance of a single copy of the sickle mutation that results from a single base pair substitution in the gene encoding the β-globin chain of hemoglobin.   More...
01 Dec 2014

HDL Cholesterol Efflux Capacity a Better Predictor of Cardiovascular Disease Risk Than Measurement of HDL or HDL Cholesterol

A recent paper strengthened the hypothesis that HDL function, rather than the absolute concentration of this lipoprotein, is the key factor linking HDL and cardiovascular disease.   More...
01 Dec 2014

The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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