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Clinical Chemistry

Sleep Apnea Severity Independently Predicts Glycemic Health

Sleep apnea has been linked with elevated blood sugar levels, suggesting people with the condition could be at an increased risk of cardiovascular illness and mortality.  More...
16 Apr 2014
Image: Cytology of pericardial fluid showing abundant, rectangular crystals corresponding to cholesterol crystals and inflammatory cells consisting of lymphocytes and macrophages (Photo courtesy of Dr. Mercedes Camprubí).

Pediatric Cholesterol Screening Needs to Be Universal

Approximately one out of three children screened for high cholesterol between the ages of 9 and 11 had borderline or high cholesterol, potentially placing them at greater risk for future cardiovascular disease.   More...
14 Apr 2014
Image: The Coulter Electronic Counter (Photo courtesy of Beckman Coulter).

Blood Iron Test Predicts Fatal Outcomes

The transferrin saturation ratio is a commonly used indicator of iron deficiency and iron overload in clinical practice, but precise relationships with total and cardiovascular mortality are equivocal.    More...
14 Apr 2014
Image: The Luminex 100/200 multiplex analyzer system (Photo courtesy of Luminex).

Blood Test Identifies Septic Shock Risk Biomarkers

A multibiomarker-based approach has been developed to estimate mortality risk in adults with septic shock and tested on blood samples from critically ill patients. More...
10 Apr 2014
Image: Schematics of protein misfolding cyclic amplification (PMCA) technology for amyloid-β (Aβ) oligomers (Photo courtesy of University of Texas Medical School).

Sensitive Biochemical Method Diagnoses Alzheimer’s Disease

A sensitive method has been used for the biochemical diagnosis of Alzheimer’s disease based on specific detection of misfolded amyloid-β oligomers, which play a central role in AD pathogenesis.    More...
09 Apr 2014
Image: The LTQ-FT Orbitrap XL Hybrid Ion Trap Mass Spectrometer (Photo courtesy of Thermo Scientific).

Proteomic Methods Diagnose Pancreatic Cancer

A method has been developed that identifies pancreatic cancer's visible precursors with 97% certainty, and is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery.    More...
08 Apr 2014
Image: The SRI 8610C gas chromatograph (Photo courtesy of SRI Instruments).

Stool Samples Provide Marker for Bowel Disease

A novel method for distinguishing different types of bowel disease using the stool samples of patients has been created which is an ideal noninvasive testing method for the diagnosis of gastro-intestinal diseases.   More...
08 Apr 2014

The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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