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Clinical Chemistry

New Approach Improves Identification of Women at High Risk of Preeclampsia

A new meta-analysis examining 92 cohort studies involving over 25 million pregnancies has provided an unprecedented understanding of risk factors for preeclampsia—some risk factors being strong enough to warrant that a pregnant woman starts on prophylactic treatment with acetylsalicylic acid (ASA) when she has only one. More...
05 May 2016

Plasma Levels Investigated as Alzheimer's Disease Biomarkers

The relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics and cognitive performance has been investigated. More...
04 May 2016

Liver Cancer May Be Diagnosed from Altered Sugar Metabolism

Altered gene expression that causes cancerous cells to metabolize fructose differently from healthy cells could be a significant new biomarker for diagnosing liver cancer. More...
04 May 2016
Image: The Q Exactive hybrid quadrupole orbitrap mass spectrometer (Photo courtesy of Thermo Fisher Scientific).

Highly Sensitive Detection Method Monitors HDL Kinetics

High-density lipoprotein (HDL) is often referred to as good cholesterol, and high levels of HDL are associated with lower risk of cardiovascular disease, but many clinical outcome trials for drugs that raise HDL levels have failed to show significant benefits for trial participants. More...
28 Apr 2016

Simple Blood Test Can Detect Injury and Mild Concussion

A simple blood has detected evidence of concussions in patients up to seven days after their injury, which could greatly expand the window for diagnosing concussions, especially in patients who experience a delayed onset of symptoms. More...
25 Apr 2016

Novel Method Detects Bacterial Infection in Preterm Infants

A new criterion has been proposed for diagnosis of bacterial infection in preterm infants and using this method could lead to early diagnosis and treatment for bacterial infection and improve the prognosis for preterm infants.  More...
12 Apr 2016

Test Predicts Death in Patients with Serious Liver Disease

Acute-on-chronic liver failure is a sudden deterioration of the liver function in a patient with liver cirrhosis accompanied by failure of one or more organ systems and this liver disease has a serious prognosis and the four-week mortality rate is 20% to 30%.  More...
12 Apr 2016

The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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