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Clinical Chemistry

Electrical Immunosensor Detects Acute Myocardial Infarction

Heart disease and especially acute myocardial infarction (AMI) are the leading causes of death for both men and women and therefore, a fast and reliable diagnosis of heart attack or cardiac episode are urgently needed. More...
25 Aug 2016
Image: Low-density lipoproteins can form the arterial plaque that is generally associated with cholesterol (Photo courtesy of the Shutterstock).

HDL High and Low Levels May Cause Premature Death

High and low levels of high-density lipoprotein (HDL) cholesterol may increase a person's risk of premature death although commonly touted as “good cholesterol” that helps to reduce risk of both stroke and heart attacks. More...
24 Aug 2016
Abbott Diagnostics
Image: A histopathology of brain tissue showing acute venous thromboembolism of unknown etiology (Photo courtesy of Peter Anderson).

Simplified Assay Quantifies Circulating Activated Protein C

The protein C (PC) anticoagulant pathway plays a crucial role in the regulation of fibrin formation by inactivating the pro-coagulant cofactors factor Va and factor VIIIa. More...
24 Aug 2016

Lab-on-a-Chip Technology Breaks New Bioparticle Separation Record

Scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale down to 20 nanometers in diameter, a scale that gives access to important particles such as DNA, viruses, and exosomes. The breakthrough could enable detection of various diseases before symptoms appear and would facilitate use of relatively noninvasive liquid biopsies. More...
23 Aug 2016
Image: The API 5000 LC/MS/MS Detector System (Photo courtesy of AB Sciex).

Biomarkers Discovered For Chronic Kidney Disease Prognosis

Chronic kidney disease (CKD) is a critical health problem and CKD patients are highly prevalent throughout the world, and the number of end-stage kidney disease (ESKD) patients, who need to receive cost-prohibitive kidney replacement therapy, is increasing year by year. More...
18 Aug 2016

Rapid Bacterial Infection Test Reduces Antibiotic Use

Inappropriate antibiotic use for acute respiratory tract infections is common in primary health care, but distinguishing serious from self-limiting infections is difficult, particularly in low-resource settings. More...
18 Aug 2016
Image: The difference between normal and osteoporotic spongy bone can be seen (Photo courtesy of Mark A. Wolgin, MD).

Bone Turnover Marker Concentrations for Osteoporosis Reviewed

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. More...
17 Aug 2016


The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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