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Clinical Chemistry

Image: The findings could pave the way for a blood test to detect risk of cognitive decline years before dementia is typically diagnosed (photo courtesy of Adobe Stock)

Blood Metabolite Test Detects Early Cognitive Decline

An AI approach using six blood metabolites detects early cognitive decline with high accuracy, guiding risk stratification. More...
06 Apr 2026
Image: Workflow of ProtAIDe-Dx on GNPC (An, L., Pichet Binette, A., Hristovska, I. et al. Nature Medicine (2026). https://doi.org/10.1038/s41591-026-04303-y)

AI-Based Blood Test Diagnose Multiple Brain Disorders from Blood Sample

An AI approach analyzes proteins in a single blood sample to detect several brain diseases simultaneously.  More...
02 Apr 2026
Image: The new MultiQ-IT prototype can cool, trap, filter, and redirect over a billion ions simultaneously, dramatically improving dynamic range and signal-to-noise (Photo courtesy of Lori Chertoff/The Rockefeller University)

Breakthrough Mass Spectrometry Design Could Enable Ultra-Low Abundance Detection

A new mass spectrometry spectoprototype can cool, trap, filter, and redirect over a billion ions simultaneously. More...
31 Mar 2026
Image: Schematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer (Photo courtesy of HUANG Guangyao)

Rapid Biosensor Detects Drug Sensitivity in Breast Tumors

Researchers have created a biosensor that quickly identifies paclitaxel sensitivity in breast cancer. More...
30 Mar 2026
Image: The assays run on the cobas i 601 analyzer as part of the cobas Mass Spec solution (photo courtesy of Roche)

New CLIA Status Brings Mass Spectrometry Steroid Testing to Routine Labs

Roche’s Ionify® steroid assays are its latest mass spectrometry tests to receive CLIA ‘moderate complexity’ classification. More...
30 Mar 2026
Image: New findings show that combining blood markers ehances both detection and staging of Alzheimer’s Disease (photo courtesy of Adobe Stock)

Study Shows Dual Biomarkers Improve Accuracy of Alzheimer’s Detection

The combination of two plasma tau markers can improve identification of Alzheimer’s disease in individuals evaluated for cognitive impairment. More...
30 Mar 2026
Image: The team behind the CASPDx project: Dr. Kieran Clarke, Commercial Lead; Dr. Emma Creagh, Associate Professor in Biochemistry at Trinity College Dublin and Scientific Lead; Prof. Glen Doherty, Consultant Gastroenterologist at St Vincent’s University Hospital; Dr Paul Leonard, Development Lead, Dublin City University (Photo courtesy of Thomas Deane, Trinity College Dublin)

Blood-Based Screening Test Targets Early Detection of Colorectal Cancer

Researchers in Ireland are developing a simple blood test for earlier colorectal cancer detection. More...
27 Mar 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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