We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
LGC Clinical Diagnostics

Download Mobile App




New Blood Test Identifies Children with Rare Heart Condition

By LabMedica International staff writers
Posted on 18 Jun 2024
Print article
Image: The new blood test could prevent sudden child deaths caused by the rare heart condition (Photo courtesy of UCL)
Image: The new blood test could prevent sudden child deaths caused by the rare heart condition (Photo courtesy of UCL)

Hypertrophic cardiomyopathy (HCM) is a hereditary condition that leads to the thickening of the heart muscle and is the most frequent cause of sudden death among children and teenagers. There is no cure for HCM, and it can occasionally lead to sudden death in young individuals. While diagnostic capabilities for this condition have significantly improved in recent years, many of the current testing methods are expensive and not widely accessible across the world. Moreover, despite significant progress in identifying children at risk of sudden cardiac death due to HCM, there remains a need for faster and more precise detection methods. A novel blood test now offers hope in identifying children afflicted by this potentially lethal heart condition.

Researchers at University College London (London, UK) have demonstrated that this new test, which measures seven specific proteins in the blood, can effectively serve as an indicator for HCM. Additionally, it can identify four proteins that are associated with a higher risk of sudden death. This breakthrough creates the possibility such a test being used to speed up the diagnosis and treatment of children with HCM. If confirmed and validated, this simple blood test that can both detect the disease and flag high-risk children with HCM could significantly enhance the management of this condition.

Typical symptoms of HCM include shortness of breath, chest pains, and palpitations, which occur as the heart muscle stiffens and becomes less efficient at pumping blood. However, many individuals with HCM may remain undiagnosed or asymptomatic. Living with this potentially dangerous condition can be challenging. Diagnosing this rare disease is complex, but obtaining a diagnosis can significantly affect the patients and their families. Ultimately, such a blood test could help more children receive timely diagnoses and access to improved treatments, potentially saving lives.

“We need to diagnose patients earlier so we can treat them sooner for a better outcome. At present, we are shutting the stable door after the horse has bolted and we need to start new therapies before patients develop symptoms. Therefore, we set out to use state-of-the-art technology to find new and better biomarkers for HCM and develop them into a test we can translate into any large NHS laboratory,” said Professor Kevin Mills from UCL Great Ormond Street Institute of Child Health. “With sufficient funding, we hope that this may be possible within two years and potentially into a simple bloodspot test that can be posted from home directly to the lab.”

Related Links: 
University College London
UCL Great Ormond Street Institute of Child Health

New
Platinum Member
Flu SARS-CoV-2 Combo Test
OSOM® Flu SARS-CoV-2 Combo Test
Magnetic Bead Separation Modules
MAG and HEATMAG
POCT Fluorescent Immunoassay Analyzer
FIA Go
Gold Member
TORCH Panel Rapid Test
Rapid TORCH Panel Test

Print article
77 ELEKTRONIKA

Channels

Clinical Chemistry

view channel
Image: The new DxC 500i Clinical Analyzer is an integrated clinical chemistry and immunoassay analyzer (Photo courtesy of Beckman Coulter Diagnostics)

Integrated Chemistry and Immunoassay Analyzer with Extensive Assay Menu Offers Flexibility, Scalability and Data Commutability

As global healthcare systems increasingly shift towards networked laboratory operational models to enhance efficiency and patient access, there is a greater need for innovative solutions tailored to the... Read more

Hematology

view channel
Image: The Truvian diagnostic platform combines clinical chemistry, immunoassay and hematology testing in a single run (Photo courtesy of Truvian Health)

Automated Benchtop System to Bring Blood Testing To Anyone, Anywhere

Almost all medical decisions are dependent upon laboratory test results, which are essential for disease prevention and the management of chronic illnesses. However, routine blood testing remains limited worldwide.... Read more

Microbiology

view channel
Image: The Simplexa C. auris direct kit is a real-time polymerase chain reaction assay run on the LIAISON MDX instrument (Photo courtesy of Diasorin)

Novel Molecular Test to Help Prevent and Control Multi Drug-Resistant Fungal Pathogen in Healthcare Settings

Candida auris (C. auris) is a rapidly emerging multi drug-resistant fungal pathogen that is commonly found in healthcare environments, where it presents a challenge due to its ability to asymptomatically... Read more

Pathology

view channel
Image: Color-enhanced scanning electron micrograph showing Salmonella Typhimurium (red) invading cultured human cells (Photo courtesy of Rocky Mountain Laboratories, NIAID, NIH)

AI Identifies Drug-Resistant Typhoid-Like Infection from Microscopy Images within Hours

Antimicrobial resistance is becoming a serious global health concern, making many infections increasingly difficult to treat and limiting available treatment options. This escalation in resistance raises... Read more

Industry

view channel
Image: Beckman Coulter will utilize the ALZpath pTau217 antibody to detect key biomarker for Alzheimer\'s disease on its DxI 9000 immunoassay analyzer (Photo courtesy of Beckman Coulter)

Beckman Coulter Licenses Alzpath's Proprietary P-tau 217 Antibody to Develop Alzheimer's Blood Test

Cognitive assessments have traditionally been the primary method for diagnosing Alzheimer’s disease, but this approach has its limitations as symptoms become apparent only after significant brain changes... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.