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Molecular Diagnostics

Image: A photomicrograph of a renal biopsy specimen suggesting acute tubular necrosis is the patchy or diffuse denudation of the renal tubular cells with loss of brush border (blue arrow) (Photo courtesy of the University of Alberta).

Autoimmune Disease Discovered Causes Kidney Failure

An insidious new autoimmune disease that causes kidney failure has been discovered. The condition causes a build-up of waste products in the blood and makes it difficult for kidneys to maintain adequate balance of fluid in the body. More...
15 Nov 2017
Image: An immunohistochemistry of PharmDX 22c3 staining of non-small-cell lung carcinoma (Photo courtesy of Agilent).

Assay Identifies Patients Benefiting from Cancer Immunotherapies

Programmed cell death ligand 1 (PD-L1) has been detected in up to 50% of all human cancers, and has become a major focus of therapeutic and biomarker studies. More...
14 Nov 2017
ELITech Group
Image: The Hitachi ABI 3130XL capillary electrophoresis genetic analyzer system (Photo courtesy of Cal-L enterprises).

Assay May Boost Treatment of Non-Hodgkin Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide. Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype. More...
14 Nov 2017
Image: A scanning electron micrograph (SEM) of breast cancer cells (Photo courtesy of SPL).

Blood Test Detects Resistance to BRCA-Targeting Drugs

Resistance to platinum-based chemotherapy or PARP inhibition in germline BRCA1 or BRCA2 mutation carriers may occur through somatic reversion mutations or intragenic deletions that restore BRCA1 or BRCA2 function. More...
14 Nov 2017
Image: A scanning electron micrograph (SEM) of an ovarian cancer cell (Photo courtesy of Steve Gschmeissner / SPL).

MicroRNA-based Assay Proposed for Early Detection of Cancer

Cancer researchers have proposed using a network of circulating microRNAs to diagnose ovarian carcinoma at a stage earlier than currently possible. More...
13 Nov 2017
Image: The Solana RSV + hMPV Assay is a rapid qualitative in vitro diagnostic test for the detection and differentiation of Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (hMPV) viral RNA (Photo courtesy of Quidel).

RSV Plus Human Metapneumovirus Assay Approved

Viral infections are the most frequent causes of morbidity and mortality due to respiratory dysfunction worldwide, especially in children under five years of age. Several studies have reported the association of Human Metapneumovirus (hMPV) and Respiratory Syncytial Virus (RSV) with acute respiratory infection. More...
09 Nov 2017
Image: A Schistosoma japonicum egg in feces (unstained, high power). The eggs of this fluke are smaller than those of S. mansoni and S. haematobium. They are ovoid and have a thin, clear shell and a spine or hook-like structure that may be inconspicuous (Photo courtesy of Florida Gulf Coast University).

Droplet Digital PCR Detects Schistosomiasis DNA in Samples

Schistosoma japonicum is the only human blood fluke that occurs in China and Philippines and also in Sri Lanka. It is the cause of schistosomiasis japonica, a disease that still remains a significant health problem especially in lake and marshland regions. More...
08 Nov 2017

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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