We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
LGC Clinical Diagnostics

Biocartis SA

Biocartis is a commercial stage molecular diagnostics company that develops diagnostics technology platforms for mult... read more Featured Products: More products

Download Mobile App




Events

09 Apr 2024 - 12 Apr 2024
15 Apr 2024 - 17 Apr 2024
23 Apr 2024 - 26 Apr 2024

Rapid CE-Marked IVD Lung Cancer Test Delivers Results Within Three Hours

By LabMedica International staff writers
Posted on 21 Jun 2022
Print article
Image: CE-marked IVD Idylla GeneFusion Panel is intended for fast treatment decisions in lung cancer (Photo courtesy of Biocartis)
Image: CE-marked IVD Idylla GeneFusion Panel is intended for fast treatment decisions in lung cancer (Photo courtesy of Biocartis)

Lung cancer remains the leading cause of cancer deaths, with non-small cell lung cancer (NSCLC) being the most common type of lung cancer. Gene fusions represent an important class of gene rearrangements and have become important in NSCLC, as they are linked to responses to certain targeted therapies. Their accurate and fast detection is critical to guide therapy choices, which is the reason why testing for gene rearrangements such as gene fusions is included in international NSCLC testing guidelines. However, comprehensive testing of actionable gene rearrangements in NSCLC is often complex and can require different technologies. In order to test all needed biomarkers, laboratories usually have to use different instruments which are often not available within their own lab. Using different instruments also requires having enough biopsy samples of sufficient good quality, which can be difficult to obtain, especially in NSCLC patients. Now, a rapid CE-marked IVD lung cancer testing solution for laboratories provides comprehensive testing results within 180 minutes, significantly faster than currently available testing methods which often take days or even weeks before results are available.

The fully automated Idylla GeneFusion Panel (CE-IVD) from Biocartis Group NV (Mechelen, Belgium) detects in one single cartridge ALK, ROS1, RET and METex14 skipping, a wide range of actionable targets relevant in NSCLC. Designed for use in clinical laboratories, the panel consolidates traditional testing workflows into one streamlined, fully-automated process. One of the biggest challenges in oncology biomarker testing is the ability to obtain samples of sufficient size and quality. However, the panel only requires a limited amount of sample, thereby saving valuable tissue specimens.

The Idylla GeneFusion Panel detects ALK, ROS1 and RET fusions & MET exon 14 skipping in a single cartridge using only 1-3 FFPE tissue sections from patients with NSCLC. By offering results in a minimum amount of time, the panel shortens the time from sample to treatment initiation to one or two days. The panel demonstrated high concordance results in a clinical comparison study where ALK was compared with IHC, and ROS1, RET and METex14 skipping were compared with NGS.

“Turnaround time and time-to-treatment remains an important barrier to molecular testing. It has been demonstrated that 10% to 20% of advanced lung cancer patients do not receive the appropriate targeted therapy because biomarker results are not provided in a timely fashion,” said Herman Verrelst, Chief Executive Officer of Biocartis.

Related Links:
Biocartis Group NV 

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
HLX
Complement 3 (C3) Test
GPP-100 C3 Kit
New
Gold Member
Magnetic Bead Separation Modules
MAG and HEATMAG

Print article

Channels

Clinical Chemistry

view channel
Image: Reaching speeds up to 6,000 RPM, this centrifuge forms the basis for a new type of inexpensive, POC biomedical test (Photo courtesy of Duke University)

POC Biomedical Test Spins Water Droplet Using Sound Waves for Cancer Detection

Exosomes, tiny cellular bioparticles carrying a specific set of proteins, lipids, and genetic materials, play a crucial role in cell communication and hold promise for non-invasive diagnostics.... Read more

Hematology

view channel
Image: The low-cost portable device rapidly identifies chemotherapy patients at risk of sepsis (Photo courtesy of 52North Health)

POC Finger-Prick Blood Test Determines Risk of Neutropenic Sepsis in Patients Undergoing Chemotherapy

Neutropenia, a decrease in neutrophils (a type of white blood cell crucial for fighting infections), is a frequent side effect of certain cancer treatments. This condition elevates the risk of infections,... Read more

Pathology

view channel
Image: The OvaCis Rapid Test discriminates benign from malignant epithelial ovarian cysts (Photo courtesy of INEX)

Intra-Operative POC Device Distinguishes Between Benign and Malignant Ovarian Cysts within 15 Minutes

Ovarian cysts represent a significant health issue for women globally, with up to 10% experiencing this condition at some point in their lives. These cysts form when fluid collects within a thin membrane... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.