We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Abbott Diagnostics- Hematology Division

CERTEST BIOTEC

Certest Biotec, S.L. develops and manufactures IVD products in the human clinical testing field, including rapid test... read more Featured Products: More products

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

New Multiplex Assay for Rapid Diagnosis of Atypical Pneumonia

By LabMedica International staff writers
Posted on 21 Sep 2021
Print article
Image: Viasure Real-time PCR kit (Photo courtesy of CerTest Biotec)
Image: Viasure Real-time PCR kit (Photo courtesy of CerTest Biotec)
CerTest Biotec (Zaragoza, Spain) has developed and validated the CE-IVD multiplex assay VIASURE C. pneumoniae, M. pneumoniae & L. pneumophila real time PCR kit for the detection of principal pathogens implicated in atypical pneumoniae.

One of the most challenging issues in the management of patients with atypical pneumoniae is the rapid identification of the microbial etiology to guide and personalize the initial antimicrobial therapy. A critical factor in the selection of a diagnostic assay for respiratory infections is the time required to obtain the test result. Only those diagnostic tests that provide results within the first 24 hours can actually assist the clinician to guide the initial antimicrobial therapy.

DNA amplification using the polymerase chain reaction (PCR) is a technique with the potential to offer rapid results in the diagnosis of bacterial pneumonia. Multiplex Real-time PCR is highly sensitive technique for the rapid detection of RNA/DNA in clinical specimens. This technique is particularly advantageous for the detection of fastidious or difficult to culture organisms such as these three atypical pathogens. Several conventional PCR assays and multiplex assays have been developed and have demonstrated sensitivity and specificity better than microbiologic tests. However, a small number of these contain the needed CE-IVD marking necessary for use in clinical diagnosis.

CerTest’s CE-IVD multiplex assay VIASURE C. pneumoniae, M. pneumoniae & L. pneumophila real time PCR detection kit has been developed and validated for the detection of the principal pathogens implicated in atypical pneumoniae. The clinical validation demonstrated that the molecular assay is a sensitive, useful, cheap, and above all a rapid diagnostic tool for the management of atypical pneumonia patients. Moreover, the type of respiratory sample is not a limiting factor as the molecular assay accurately detects the pathogens in upper and lower respiratory samples. Additionally, the multiplex strategy offers an obvious and important clinical advantage as it minimizes the risk that the causative search is biased by overlapping clinical presentations of distinct causes. The application of the CE-IVD multiplex assay VIASURE C. pneumoniae, M. pneumoniae & L. pneumophila real time PCR detection kit from CerTest is expected to significantly improve diagnostics for atypical pneumonia-associated bacterial pathogens.

 

Related Links:

CerTest Biotec


Gold Supplier
Fluorimetric Immunoassay Analyzer
Confiscope F20
New
Bench-Top Molecular Microarray System
NanoCHIP XL Analyzer
New
Auto Multiparameter POC Analyzer
Triage MeterPro
New
Semi-Automated Coagulation Analyzer
Thrombo Fast+

Print article

Channels

Molecular Diagnostics

view channel
Image: Absence of nuclear immunohistochemical staining of MSH2 protein (A) and presence of MLH1 protein (B) in urothelial cell carcinoma of the urinary bladder of a patient carrying a germline MSH2 mutation. Observe the nuclear staining in stromal cells as an internal control (Photo courtesy of Radboud University Nijmegen Medical Centre)

Simple Urine Test Detects Urothelial Cancers in Lynch Syndrome Patients

Lynch Syndrome (LS) is an inherited genetic disorder that carries a high risk of cancer. LS is caused by mutations affecting MLH1, MSH2, MSH6 or PMS2 genes. More than one in 300 people have LS but most... Read more

Hematology

view channel
Image: The Gazelle Hb Variant Test for screening, diagnosis and management of sickle cell disease and related hemoglobinopathies at the point of care (Photo courtesy of Hemex Health)

Point-of-Care Device Accurately Rapidly Diagnoses Sickle Cell Disease

Hemoglobinopathies are the most common autosomal hereditary disorders. Approximately 7% of the global population carries hemoglobin gene mutation including structural hemoglobin variants like sickle hemoglobin... Read more

Immunology

view channel
Image: The IMMULITE 2000 XPi Immunoassay System provides multiple tests on a single, easy-to-use analyzer, including the thyroid-stimulating immunoglobulin assay (Photo courtesy of Siemens Healthcare)

Immunoassays Evaluated for Thyroid-Stimulating Receptor Antibody in Graves’ Disease

Graves' disease (GD), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism and it also often results... Read more

Microbiology

view channel
Image: The sciREADER CL2 enables high quality digital colorimetric imaging of various support formats (Photo courtesy of SCIENION)

Multiplex Immunoassay Developed for Confirmation and Typing of HTLV Infections

Human T-Cell Lymphotropic Viruses (HTLV) type 1 and type 2 account for an estimated five to 10 million infections worldwide and are transmitted through breast feeding, sexual contacts and contaminated... Read more

Pathology

view channel
Illustration

AI Accurately Detects and Diagnoses Colorectal Cancer from Tissue Scans As Well or Better Than Pathologists

Artificial intelligence (A) can accurately detect and diagnose colorectal cancer from tissue scans as well or better than pathologists, according to a new study. The study, which was conducted by researchers... Read more

Technology

view channel
Image: PKeye Workflow Monitor System (Photo courtesy of PerkinElmer, Inc.)

PerkinElmer’s New Cloud-Based Platform Enables Laboratory Personnel to Remotely Manage Its Instruments in Real-Time

PerkinElmer, Inc. (Waltham, MA; USA) has launched its PKeye Workflow Monitor, a cloud-based platform enabling laboratory personnel to remotely manage and monitor their PerkinElmer instruments and workflows... Read more

Industry

view channel
Illustration

Global Point of Care Diagnostics Market to Top USD 35 Billion by 2027 Due to Rising Diabetic Cases

The global point of care diagnostics market is projected to grow at a CAGR of close to 6% from more than USD 23 billion in 2020 to over USD 35 billion by 2027, driven by an increase in the number of diabetic... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.