We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
RANDOX LABORATORIES

Download Mobile App




全部基因DNA数据瞬间可得

By LabMedica International staff writers
Posted on 03 Dec 2013
Print article
一款新设备能从唾液拭子中提取人的DNA,只需几分钟就能提供全部的分析数据和基因组测序数据。

美国华盛顿州西雅图的华盛顿大学和NanoFacture公司(Bellevue, WA, USA)的科研人员开发的这种新设备用显微探针浸入唾液、痰液或血液等液体样本,并给液体加上电场,吸引粒子在探针表面周围聚集。较大的粒子碰到针尖并转向,但和DNA差不多大的分子粘到探针上,通过毛细管作用被表面捕获。用这项技术分离和提纯DNA只需两三分钟。

这款手持式设备一次能清理四份人体液样本,但这项技术经过扩展后一次可制备96份样本,这是大规模处理的标准规格。华盛顿大学的工程师们还利用同样的探针技术设计了一种像铅笔一样大的设备,病人可以戴着它回家,也可以把它发给海外服役的军人。病人可以刮拭面颊,收集唾液样本,并在现场处理DNA,然后送回医院和化验室分析。

首席研究员、华盛顿大学机械工程系副教授Jae-Hyun Chung博士说:“提取DNA非常复杂。目前的过程就像用起重机收集人的头发。”

传统方法用离心机旋转并分离DNA分子,或用微型滤器从液体样本中拉出DNA分子,但这些过程需要20到30分钟才能完成,可能还需要用到过多的有毒化学品。医院和研究实验室用新设备更容易从人体液样本中分离DNA,从而有助于基因组测序、疾病诊断和法医调查。

Related Links:
美国华盛顿州西雅图的华盛顿大学
NanoFacture

Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
Complement 3 (C3) Test
GPP-100 C3 Kit
New
Gold Member
TORCH Panel Rapid Test
Rapid TORCH Panel Test

Print article

Channels

Clinical Chemistry

view channel
Image: The 3D printed miniature ionizer is a key component of a mass spectrometer (Photo courtesy of MIT)

3D Printed Point-Of-Care Mass Spectrometer Outperforms State-Of-The-Art Models

Mass spectrometry is a precise technique for identifying the chemical components of a sample and has significant potential for monitoring chronic illness health states, such as measuring hormone levels... Read more

Hematology

view channel
Image: The CAPILLARYS 3 DBS devices have received U.S. FDA 510(k) clearance (Photo courtesy of Sebia)

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Hemoglobinopathies, the most widespread inherited conditions globally, affect about 7% of the population as carriers, with 2.7% of newborns being born with these conditions. The spectrum of clinical manifestations... Read more

Immunology

view channel
Image: Exosomes can be a promising biomarker for cellular rejection after organ transplant (Photo courtesy of Nicolas Primola/Shutterstock)

Diagnostic Blood Test for Cellular Rejection after Organ Transplant Could Replace Surgical Biopsies

Transplanted organs constantly face the risk of being rejected by the recipient's immune system which differentiates self from non-self using T cells and B cells. T cells are commonly associated with acute... Read more

Microbiology

view channel
Image: Microscope image showing human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color (Photo courtesy of Fred Hutch Cancer Center)

Mouth Bacteria Test Could Predict Colon Cancer Progression

Colon cancer, a relatively common but challenging disease to diagnose, requires confirmation through a colonoscopy or surgery. Recently, there has been a worrying increase in colon cancer rates among younger... Read more

Pathology

view channel
Image: Fingertip blood sample collection on the Babson Handwarmer (Photo courtesy of Babson Diagnostics)

Unique Hand-Warming Technology Supports High-Quality Fingertip Blood Sample Collection

Warming the hand is an effective way to facilitate blood collection from a fingertip, yet off-the-shelf solutions often do not fulfill laboratory requirements. Now, a unique hand-warming technology has... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.