Features | Partner Sites | Information | LinkXpress
Sign In
FOCUS DIAGNOSTICS, INC.
Biostrata Ltd on behalf of Thermo
RANDOX LABORATORIES

Point-of-Care Device Compared for Cardiac Troponin Assay

By Labmedica International staff writers
Posted on 02 Oct 2013
Image: The i-STAT portable clinical analyzer system (Photo courtesy of Abbot Laboratories).
Image: The i-STAT portable clinical analyzer system (Photo courtesy of Abbot Laboratories).
A fingerstick point-of-care (POC) testing for cardiac troponin I has been compared to conventional venipuncture POC testing.

Cardiac troponin assays commonly exceed one hour while point-of-care testing can be completed in minutes by basic life support personnel so when patients present complaining of chest pain, time can be critical to achieving positive outcomes.

Scientists at the Loyola University Medical Center (Maywood, IL, USA) collected fingerstick blood samples from consenting patients for whom standard-of-care venipuncture POC troponin (POCT) testing had been ordered as part of their workup. Cardiac troponin (cTnl) assays were performed using a commercial device from June to August 2011. Eighty-nine cTnI levels were measured by both fingerstick and standard venipuncture emergency department POC testing. Four resulted in cartridge error so only the remaining 85 were analyzed.

Cardiac troponin I (cTnI) assays were performed using an i-STAT 1 device (Abbott Point of Care; Princeton, NJ, USA). Fingerstick testing, compared with standard ED POCT, has a positive predictive value of 1.00 (0.48, 1.00), a negative predictive value of 0.96 (0.89, 0.99), a sensitivity of 0.625 (0.24, 0.91), and a specificity of 1.00 (0.95, 1.00). The relationship between methods appeared to be linear.

The authors concluded that fingerstick cTnI testing using the i-STAT device is not accurate enough to determine the exact troponin level without the application of a corrective term. Fingerstick testing is, however, accurate in qualifying troponin levels as negative, borderline, or positive and is, therefore, capable of providing clinical information that may guide diagnostic and therapeutic decision-making. The study was published in the August 2013 issue of the American Journal of Emergency Medicine.

Related Links:
Loyola University Medical Center
Abbott Point of Care



EUROIMMUN AG
KARL HECHT GMBH & CO KG
DIASYS DIAGNOSTIC SYSTEMS
WATERS CORPORATION

Channels

Genetic Tests

view channel
Image: The fully automated nCounter Analysis System (Photo courtesy of NanoString Technologies).

Blood Signature Analysis Helps Diagnose Parkinson’s Disease Earlier

The diagnosis of Parkinson's is usually not established until advanced neurodegeneration leads to clinically detectable symptoms involving the malfunction and death of vital nerve cells in the brain.... Read more

Pathology

view channel
Image: The cobas KRAS mutation real-time polymerase chain reaction test (Photo courtesy of Roche).

KRAS Mutation Test for Colorectal Cancer Diagnosis Approved

A real-time polymerase chain reaction test has been designed to identify the Kirsten rat sarcoma viral oncogene (KRAS) mutations in tumor samples from metastatic colorectal cancer (mCRC) patients and aid... Read more

Industry News

view channel

Main Factors Driving Revenue Growth in Clinical Chemistry Identified

According to a report by Kalorama Information (New York, NY, USA), overall growth in the clinical chemistry market will be modest, driven mainly by new tests and demographic changes, including an aging population and increasing number of people at risk of cardiovascular disease, such as those with hypertension, diabetes... Read more
 
Copyright © 2000-2015 Globetech Media. All rights reserved.