Features | Partner Sites | Information | LinkXpress
Sign In
AB Sciex
FOCUS DIAGNOSTICS, INC.
RANDOX LABORATORIES

Noninvasive Prenatal Test Screens Blood for Chromosomal Abnormalities

By Labmedica International staff writers
Posted on 27 Feb 2013
Physicians will have access to a new noninvasive prenatal test, which uses cell-free fetal DNA in circulating maternal blood.

The test, called Panorama, uses cell-free fetal DNA in circulating maternal blood to screen for chromosomal abnormalities associated with trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome) and monosomy X (Turner syndrome). Panorama can be used as early as the ninth week of pregnancy.

Quest Diagnostics (Madison, NJ, USA), a diagnostic information services company, and Natera (San Carlos, CA, USA), an innovator in prenatal genetic testing, announced that Quest Diagnostics will offer physicians access to Panorama, the new noninvasive prenatal test developed by Natera.

Physician will be able to forward specimens for testing to Natera's Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory in San Carlos (CA, USA), which developed and validated the lab-developed Panorama test. The test will be made available to physician clients of Quest Diagnostics in certain regions in March and nationwide in the United States in April 2013.

In December 2012, the American Congress of Obstetricians and Gynecologists (ACOG) issued a medical opinion stating that cell-free fetal DNA testing is one option that can be used as a primary screening test in women at increased risk of aneuploidy. It may also be offered as a follow-up test for women with a positive first-trimester or second-trimester screening test result.

A “low risk” Panorama test result indicates a lower likelihood that a pregnancy is affected. With this information, a woman may consider, in consultation with her physician and results of other medical assessments, whether to pursue or forgo invasive diagnostic testing, which carries a slight risk of miscarriage. A “low risk” Panorama result does not guarantee an unaffected pregnancy.

"Cell-free fetal DNA testing is a significant advance in prenatal screening," said Charles Strom, MD, PhD, senior medical director, genetics, Quest Diagnostics Nichols Institute. "By offering physicians and women access to Panorama, Quest Diagnostics is delivering on its commitment to provide clinically important innovations aligned with guideline-based care."

Natera is a leading genetic testing company that has developed a proprietary bioinformatics-based technology (NATUS) to deliver accurate and comprehensive high-throughput testing for reproductive indications from minute quantities of DNA. Natera operates a CLIA-certified laboratory in San Carlos (CA, USA) providing a host of preconception and prenatal genetic testing services.

Related Links:
Quest Diagnostics
Natera




ADVANCED INSTRUMENTS
VIRCELL
DiagCor Bioscience
comments powered by Disqus
Life Technologies

Channels

Immunology

view channel
Image: The Zinc Transporter 8 Autoantibody (ZnT8Ab) enzyme-linked immunosorbent assay (ELISA) kit (Photo courtesy of KRONUS).

Autoantibody Test Helps Diagnose Type 1 Diabetes

The first zinc transporter 8 autoantibody (ZnT8Ab) test has been approved for marketing and the test can help determine if a person has diabetes mellitus type 1 and not another type of diabetes.... Read more

Industry News

view channel

Funding Awarded to Develop Diagnostic Point-of-Care Device for Sickle Cell Disease

Rockland Immunochemicals, Inc. (Limerick, PA, USA) has announced the award of a USD 224,473 Small Business Innovation Research (SBIR) grant from the NIH National Heart Lung and Blood Institute (NHLBI) to develop an antibody-based point-of-care device for the diagnosis of Sickle Cell Disease (SCD), a mutation carried in... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.