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Genetic Tests

Blood Test Could Predict Best Treatment for Lung Cancer

A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment. In most patients with SCLC, a metastatic, aggressive disease, the condition is initially chemosensitive, but then relapses with acquired chemoresistance. More...
09 Dec 2016
Image: Chromosome ideograms showing some locations of genome-wide significant linkages in schizophrenia and bipolar disorder. Asterisks mark the locations of chromosomal abnormalities associated with schizophrenia (Photo courtesy of SPL).

Rare Genetic Variations Linked to Schizophrenia

Genetic variations that increase schizophrenia risk are rare, making it difficult to study their role and to overcome this. Recently, the genomes of more than 41,000 people have been analyzed in the largest study of its kind to date. More...
09 Dec 2016
Image: A stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia (Photo courtesy of VashiDonsk).

Genetic Testing Identifies High-Risk Subtype of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is less common in adults than in children, but adults are far less likely to survive. Adults make up about 40% of the estimated 6,590 new cases of ALL identified annually in the USA. More...
09 Dec 2016

Specific Gene Expression Differentiates Moles from Melanoma

Most melanomas are driven by mutations that spur out-of-control cell replication, while nevi which are moles composed of non-cancerous cells at the skin surface, that harbor the same mutations do not grow wildly. More...
08 Dec 2016

Diagnostic Tool Designed for Familial Mediterranean Fever

A tool has been developed to diagnose Familial Mediterranean Fever (FMF) which is particularly common among populations originating from around Mediterranean Sea and this genetic disease is characterized by inflammation, fever and severe pain. More...
08 Dec 2016
Image: Indirect immunofluorescence on a patient’s intestinal lining shows anti-enterocyte antibodies. Enterocytes are the cells of the intestinal lining (Photo courtesy of the NIH).

Successful Treatment of Enteritis Due to Newly Discovered Gene Mutation

Researchers report successful treatment of an adult patient with severe chronic autoimmune enteritis by using the drug Vedolizumab to target the effect on T-cell function of a mutation identified in the patient’s CTLA-4 gene. Vedolizumab may also help skin cancer patients with enteritis due to therapy with Ipilimumab. More...
07 Dec 2016

Multiple Biopsies Recommended for Personalized Breast Cancer Treatments

Assessment of somatic mutations is becoming increasingly important for the management of cancer patients, but molecular heterogeneity occurs across many tumors. In breast cancer, there is major interest in the use of pre-surgical studies for assessing the biological effect of therapeutic agents. More...
01 Dec 2016

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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